TMEM106B p.T185S regulates TMEM106B protein levels: Implications for frontotemporal dementia

Journal of Neurochemistry

Volumn 126, Issue 6, 2013, Pages 781-791

  Nicholson, Alexandra M ^a   Finch, Nicole A ^a   Wojtas, Aleksandra ^a   Baker, Matt C ^a   Perkerson III, Ralph B ^a   Castanedes Casey, Monica ^a   Rousseau, Linda ^a   Benussi, Luisa ^b   Binetti, Giuliano ^b   Ghidoni, Roberta ^b   Hsiung, Ging Yuek R ^c   Mackenzie, Ian R ^c   Finger, Elizabeth ^d   Boeve, Bradley F ^e   Ertekin Taner, Nilüfer ^a,f   Graff Radford, Neill R ^f   Dickson, Dennis W ^a   Rademakers, Rosa ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d WESTERN UNIVERSITY   (Canada)

^e MAYO CLINIC   (United States)

^f MAYO CLINIC   (United States)

Author keywords

frontotemporal dementia; glycosylation; progranulin; TMEM106B

Indexed keywords

CYCLOHEXIMIDE; PROGRANULIN; TMEM106B PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO ACID SEQUENCE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENE OVEREXPRESSION; GENETIC RISK; GENETIC VARIABILITY; HETEROZYGOTE; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN GLYCOSYLATION; REGULATORY MECHANISM; TMEM106B GENE;

FRONTOTEMPORAL DEMENTIA; GLYCOSYLATION; PROGRANULIN; TMEM106B;

AGED; BLOTTING, WESTERN; CELLS, CULTURED; COHORT STUDIES; DNA, COMPLEMENTARY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FRONTOTEMPORAL DEMENTIA; GENOTYPE; GLYCOSYLATION; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOMERISM; LYSOSOMES; MALE; MEMBRANE PROTEINS; MUTAGENESIS; MUTATION; NERVE TISSUE PROTEINS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84883742170     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12329     Document Type: Article

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