Quantitative FLAIR analysis indicates predominant affection of the amygdala in antibody-associated limbic encephalitis

Epilepsia

Volumn 54, Issue 9, 2013, Pages 1679-1687

  Wagner, Jan ^a,b   Schoene Bake, Jan Christoph ^a,b,c   Malter, Michael P ^a   Urbach, Horst ^a   Huppertz, Hans Jürgen ^d   Elger, Christian E ^a,b   Weber, Bernd ^a,b  

^a UNIVERSITY OF BONN   (Germany)

^b Life and Brain Center   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d SWISS EPILEPSY CENTER   (Switzerland)

Author keywords

Epilepsy; Hippocampal sclerosis; Magnetic resonance imaging; Postprocessing

Indexed keywords

ADOLESCENT; ADULT; AGED; AMYGDALOID NUCLEUS; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; FEMALE; FLUID ATTENUATED INVERSION RECOVERY; HIPPOCAMPAL SCLEROSIS; HIPPOCAMPUS; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; NEURORADIOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PARANEOPLASTIC NEUROPATHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOLOGICAL PARAMETERS; SENSITIVITY AND SPECIFICITY;

EPILEPSY; HIPPOCAMPAL SCLEROSIS; MAGNETIC RESONANCE IMAGING; POSTPROCESSING;

ADOLESCENT; ADULT; AGED; AMYGDALA; ELECTROENCEPHALOGRAPHY; EPILEPSY, TEMPORAL LOBE; FEMALE; HIPPOCAMPUS; HUMANS; LIMBIC ENCEPHALITIS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; SCLEROSIS; YOUNG ADULT;

EID: 84883741087     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.12320     Document Type: Article

References (38)

1. Bartlett PA, Richardson MP, Duncan JS,. (2002) Measurement of amygdala T2 relaxation time in temporal lobe epilepsy. J Neurol Neurosurg Psychiatry 73: 753-755.
2. Bernasconi N, Bernasconi A, Caramanos Z, Antel SB, Andermann F, Arnold DL,. (2003) Mesial temporal damage in temporal lobe epilepsy: a volumetric MRI study of the hippocampus, amygdala and parahippocampal region. Brain 126: 462-469.
3. Bien CG, Urbach H, Schramm J, Soeder BM, Becker AJ, Voltz R, Vincent A, Elger CE,. (2007) Limbic encephalitis as a precipitating event in adult-onset temporal lobe epilepsy. Neurology 69: 1236-1244.
4. Bien CG, Vincent A, Barnett MH, Becker AJ, Blumcke I, Graus F, Jellinger KA, Reuss DE, Ribalta T, Schlegel J, Sutton I, Lassmann H, Bauer J,. (2012) Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis. Brain 135: 1622-1638.
5. Blond BN, Fredericks CA, Blumberg HP,. (2012) Functional neuroanatomy of bipolar disorder: structure, function, and connectivity in an amygdala-anterior paralimbic neural system. Bipolar Disord 14: 340-355.
6. Briellmann RS, Jackson GD, Pell GS, Mitchell LA, Abbott DF,. (2004) Structural abnormalities remote from the seizure focus: a study using T2 relaxometry at 3 T. Neurology 63: 2303-2308.
7. Briellmann RS, Hopwood MJ, Jackson GD,. (2007) Major depression in temporal lobe epilepsy with hippocampal sclerosis: clinical and imaging correlates. J Neurol Neurosurg Psychiatry 78: 1226-1230.
8. Brierley JB, Corsellis JAN, Hierons R, Nevin S,. (1960) Subacute encephalitis of later adult life mainly affecting the limbic areas. Brain 83: 357-368.
9. Chan S, Chin SS, Kartha K, Nordli DR, Goodman RR, Pedley TA, Hilal SK,. (1996) Reversible signal abnormalities in the hippocampus and neocortex after prolonged seizures. AJNR 17: 1725-1731.
10. Dalmau J, Rosenfeld MR,. (2008) Paraneoplastic syndromes of the CNS. Lancet Neurol 7: 327-340.
11. Dalmau J, Tuzun E, Wu HY, Masjuan J, Rossi JE, Voloschin A, Baehring JM, Shimazaki H, Koide R, King D, Mason W, Sansing LH, Dichter MA, Rosenfeld MR, Lynch DR,. (2007) Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol 61: 25-36.
12. Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M, Dessain SK, Rosenfeld MR, Balice-Gordon R, Lynch DR,. (2008) Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol 7: 1091-1098.
13. Demaerel P, Van Dessel W, Van Paesschen W, Vandenberghe R, Van Laere K, Linn J,. (2011) Autoimmune-mediated encephalitis. Neuroradiology 53: 837-851.
14. Focke NK, Symms MR, Burdett JL, Duncan JS,. (2008) Voxel-based analysis of whole brain FLAIR at 3T detects focal cortical dysplasia. Epilepsia 49: 786-793.
15. Focke NK, Bonelli SB, Yogarajah M, Scott C, Symms MR, Duncan JS,. (2009) Automated normalized FLAIR imaging in MRI-negative patients with refractory focal epilepsy. Epilepsia 50: 1484-1490.
16. Gultekin SH, Rosenfeld MR, Voltz R, Eichen J, Posner JB, Dalmau J,. (2000) Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients. Brain 123 (Pt 7): 1481-1494.
17. Huppertz HJ, Wagner J, Weber B, House P, Urbach H,. (2011) Automated quantitative FLAIR analysis in hippocampal sclerosis. Epilepsy Res 97: 146-156.
18. Irani SR, Michell AW, Lang B, Pettingill P, Waters P, Johnson MR, Schott JM, Armstrong RJ, Zagami A, Bleasel A, Somerville ER, Smith SM, Vincent A,. (2011) Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis. Ann Neurol 69: 892-900.
19. Jenkinson M, Beckmann CF, Behrens TE, Woolrich MW, Smith SM,. (2012) Fsl. Neuroimage 62: 782-790.
20. Johnson N, Henry C, Fessler AJ, Dalmau J,. (2010) Anti-NMDA receptor encephalitis causing prolonged nonconvulsive status epilepticus. Neurology 75: 1480-1482.
21. Khan NL, Jeffree MA, Good C, Macleod W, Al-Sarraj S,. (2009) Histopathology of VGKC antibody-associated limbic encephalitis. Neurology 72: 1703-1705.
22. Lawn ND, Westmoreland BF, Kiely MJ, Lennon VA, Vernino S,. (2003) Clinical, magnetic resonance imaging, and electroencephalographic findings in paraneoplastic limbic encephalitis. Mayo Clin Proc 78: 1363-1368.
23. Malter MP, Helmstaedter C, Urbach H, Vincent A, Bien CG,. (2010) Antibodies to glutamic acid decarboxylase define a form of limbic encephalitis. Ann Neurol 67: 470-478.
24. McCoy B, Akiyama T, Widjaja E, Go C,. (2011) Autoimmune limbic encephalitis as an emerging pediatric condition: case report and review of the literature. J Child Neurol 26: 218-222.
25. Mitsueda-Ono T, Ikeda A, Inouchi M, Takaya S, Matsumoto R, Hanakawa T, Sawamoto N, Mikuni N, Fukuyama H, Takahashi R,. (2011) Amygdalar enlargement in patients with temporal lobe epilepsy. J Neurol Neurosurg Psychiatry 82: 652-657.
26. Niehusmann P, Dalmau J, Rudlowski C, Vincent A, Elger CE, Rossi JE, Bien CG,. (2009) Diagnostic value of N-methyl-D-aspartate receptor antibodies in women with new-onset epilepsy. Arch Neurol 66: 458-464.
27. Novillo-Lopez ME, Rossi JE, Dalmau J, Masjuan J,. (2008) Treatment-responsive subacute limbic encephalitis and NMDA receptor antibodies in a man. Neurology 70: 728-729.
28. Provenzale JM, Barboriak DP, Coleman RE,. (1998) Limbic encephalitis: comparison of FDG PET and MR imaging findings. Am J Roentgenol 170: 1659-1660.
29. Pruss H, Dalmau J, Harms L, Holtje M, Ahnert-Hilger G, Borowski K, Stoecker W, Wandinger KP,. (2010) Retrospective analysis of NMDA receptor antibodies in encephalitis of unknown origin. Neurology 75: 1735-1739.
30. Quek AM, Britton JW, McKeon A, So E, Lennon VA, Shin C, Klein C, Watson RE Jr, Kotsenas AL, Lagerlund TD, Cascino GD, Worrell GA, Wirrell EC, Nickels KC, Aksamit AJ, Noe KH, Pittock SJ,. (2012) Autoimmune epilepsy: clinical characteristics and response to immunotherapy. Arch Neurol 69: 582-593.
31. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TE, Johansen-Berg H, Bannister PR, De Luca M, Drobnjak I, Flitney DE, Niazy RK, Saunders J, Vickers J, Zhang Y, De Stefano N, Brady JM, Matthews PM,. (2004) Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 23 (Suppl. 1): S208-S219.
32. Strakowski SM, Adler CM, Almeida J, Altshuler LL, Blumberg HP, Chang KD, DelBello MP, Frangou S, McIntosh A, Phillips ML, Sussman JE, Townsend JD,. (2012) The functional neuroanatomy of bipolar disorder: a consensus model. Bipolar Disord 14: 313-325.
33. Titulaer MJ, McCracken L, Gabilondo I, Armangue T, Glaser C, Iizuka T, Honig LS, Benseler SM, Kawachi I, Martinez-Hernandez E, Aguilar E, Gresa-Arribas N, Ryan-Florance N, Torrents A, Saiz A, Rosenfeld MR, Balice-Gordon R, Graus F, Dalmau J,. (2013) Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. Lancet Neurol 12: 157-165.
34. Urbach H,. (2012) High-field magnetic resonance imaging for epilepsy. Neuroimaging Clin N Am 22: 173-189, ix-x.
35. Urbach H, Soeder BM, Jeub M, Klockgether T, Meyer B, Bien CG,. (2006) Serial MRI of limbic encephalitis. Neuroradiology 48: 380-386.
36. van Vliet J, Mulleners W, Meulstee J,. (2012) EEG leading to the diagnosis of limbic encephalitis. Clin EEG Neurosci 43: 161-164.
37. Vincent A, Buckley C, Schott JM, Baker I, Dewar BK, Detert N, Clover L, Parkinson A, Bien CG, Omer S, Lang B, Rossor MN, Palace J,. (2004) Potassium channel antibody-associated encephalopathy: a potentially immunotherapy- responsive form of limbic encephalitis. Brain 127: 701-712.
38. Vincent A, Bien CG, Irani SR, Waters P,. (2011) Autoantibodies associated with diseases of the CNS: new developments and future challenges. Lancet Neurol 10: 759-772.