Clinical data support that psyllium is not fermented in the gut

American Journal of Gastroenterology

Volumn 108, Issue 9, 2013, Pages 1541-

  McRorie, Johnson ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULOSE; GUAR GUM; ISPAGULA; METHYLCELLULOSE; PECTIN;

CLINICAL ASSESSMENT; CLINICAL STUDY; DRUG DECOMPOSITION; ENZYMATIC DEGRADATION; FLATULENCE; GEL; IN VITRO STUDY; IN VIVO STUDY; INTESTINE; LETTER; PRIORITY JOURNAL; SHEAR STRESS; STEREOSPECIFICITY;

DIETARY FIBER; FERMENTATION; GASTROINTESTINAL TRACT; HUMANS; PSYLLIUM;

EID: 84883728623     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2013.211     Document Type: Letter

References (9)

1. Eswaran S , Muir J , Chey WD. Fiber and functional gastrointestinal disorders. Am J Gastroenterol 2013 ; 108 : 718-27.
2. Campbell J , Fahey G. Psyllium and methylcellulose fermentation properties in relation to insoluble and soluble fi ber standards. Nutr Res 1997 ; 17 : 619-29.
3. Kaur A , Rose D , Rumpagaporn P et al. In vitro batch fecal fermentation comparison of gas and short-chain fatty acid production using " slowly fermentable " dietary fi bers. J Food Sci 2011 ; 76 : H137-42.
4. Timm D , Stewart M , Hospattankar A et al. Wheat dextrin, psyllium, and inulin produce distinct fermentation patterns, gas volumes, and short-chain fatty acid profi les in vitro. J Med Food 2010 ; 13 : 961-6.
5. Wolever T , ter Wal P , Spadafora P et al. Guar, but not psyllium, increases breath methane and serum acetate concentrations in human subjects. Am J Clin Nutr 1992 ; 55 : 719-22.
6. Levitt MD , Furne J , Olsson S. The relation of passage of gas and abdominal bloating to colonic gas production. Ann Intern Med 1996 ; 124 : 422-4.
7. Zumarraga L , Levitt M , Suarez F. Absence of gaseous symptoms during ingestion of commercial fi bre preparations. Aliment Pharmacol Ther 1997 ; 11 : 1067-72.
8. Wolever T , Robb P. Effect of guar, pectin, psyllium, soy polysaccharide and cellulose on breath hydrogen and methane in healthy subjects. Am J Gastroenterol 1992 ; 87 : 305-10.
9. Marteau P , Flouri é B , Cherbut C et al. Digestibility and bulking Effect of ispaghula husks in healthy humans. Gut 1994 ; 35 : 1747-52.