Glycan Structures Contain Information for the Spatial Arrangement of Glycoproteins in the Plasma Membrane

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Hall, M Kristen ^a   Weidner, Douglas A ^a   Chen, Jian ming ^a   Bernetski, Christopher J ^a   Schwalbe, Ruth A ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCAN; GLYCOPROTEIN; GLYCOSIDASE; GREEN FLUORESCENT PROTEIN; LECTIN; MANNOSE OLIGOSACCHARIDE; PROTEIN KV3.1; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL ADHESION; CELL ASSAY; CELL INTERACTION; CELL MIGRATION; CELL MUTANT; CELL SURFACE; CHO CELL; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME SPECIFICITY; FEMALE; FLUORESCENCE; GLYCOSYLATION; HETEROLOGOUS EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHASE CONTRAST MICROSCOPY; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; WESTERN BLOTTING;

ANIMALS; CADHERINS; CELL ADHESION; CELL MEMBRANE; CELL MOVEMENT; CHO CELLS; CRICETINAE; CRICETULUS; GENETIC VECTORS; GLYCOPROTEINS; GLYCOSYLATION; GREEN FLUORESCENT PROTEINS; LECTINS; MICROSCOPY, FLUORESCENCE; MUTATION; POLYMERS; POLYSACCHARIDES; SHAW POTASSIUM CHANNELS;

EID: 84883642451     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075013     Document Type: Article

References (29)

1. Apweiler R, Hermjakob H, Sharon N, (1999) On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database. Biochim Biophys Acta 1473: 4-8.
2. Varki A, Lowe J (2009) Biological Roles of Glycans. In: Varki A, Cummings R, Esko J, Freeze H, Stanley P, et al., Essentials of Glycobiology. 2nd ed. Cold Spring Harbor: Cold Spring Harbor Laboratory Press. Chapter 6.
3. Jaeken J, (2010) Congenital disorders of glycosylation. Ann N Y Acad Sci 1214: 190-198.
4. Bhattacharyya R, Bhaumik M, Raju TS, Stanley P, (2002) Truncated, inactive N-acetylglucosaminyltransferase III (GlcNAc-TIII) induces neurological and other traits absent in mice that lack GlcNAc-TIII. J Biol Chem 277: 26300-26309.
5. Ioffe E, Stanley P, (1994) Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc Natl Acad Sci U S A 91: 728-732.
6. Wang Y, Tan J, Sutton-Smith M, Ditto D, Panico M, et al. (2001) Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. Glycobiology 11: 1051-1070.
7. Leckband D, Sivasankar S, (2012) Cadherin recognition and adhesion. Curr Opin Cell Biol 24: 620-627.
8. Zhao H, Liang Y, Xu Z, Wang L, Zhou F, et al. (2008) N-glycosylation affects the adhesive function of E-Cadherin through modifying the composition of adherens junctions (AJs) in human breast carcinoma cell line MDA-MB-435. J Cell Biochem 104: 162-175.
9. Cartwright TA, Corey MJ, Schwalbe RA, (2007) Complex oligosaccharides are N-linked to Kv3 voltage-gated K+ channels in rat brain. Biochim Biophys Acta 1770: 666-671.
10. Ednie AR, Bennett ES, (2012) Modulation of Voltage-Gated Ion Channels by Sialylation. Comprehensive Physiology 2: 1269-1301.
11. Hall MK, Cartwright TA, Fleming CM, Schwalbe RA, (2011) Importance of glycosylation on function of a potassium channel in neuroblastoma cells. PLoS One 6: e19317.
12. Stanley P, Schachter H, Taniguchi N (2009) N-Glycans. In: Varki A, Cummings R, Esko J, Freeze H, Stanley P, et al., Essentials of Glycobiology. 2nd ed. Cold Spring Harbor: Cold Spring Harbor Laboratory Press. Chapter 8.
13. Patnaik SK, Stanley P, (2006) Lectin-resistant CHO glycosylation mutants. Methods Enzymol 416: 159-182.
14. North SJ, Huang HH, Sundaram S, Jang-Lee J, Etienne AT, et al. (2010) Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. J Biol Chem 285: 5759-5775.
15. Cartwright TA, Schwalbe RA, (2009) Atypical sialylated N-glycan structures are attached to neuronal voltage-gated potassium channels. Biosci Rep 29: 301-313.
16. Schwalbe RA, Corey MJ, Cartwright TA, (2008) Novel Kv3 glycoforms differentially expressed in adult mammalian brain contain sialylated N-glycans. Biochem Cell Biol 86: 21-30.
17. Hirabayashi S, Tajima M, Yao I, Nishimura W, Mori H, et al. (2003) JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. Mol Cell Biol 23: 4267-4282.
18. Brooks NL, Corey MJ, Schwalbe RA, (2006) Characterization of N-glycosylation consensus sequences in the Kv3.1 channel. Febs J 273: 3287-3300.
19. Hall MK, Reutter W, Lindhorst T, Schwalbe RA, (2011) Biochemical engineering of the N-acyl side chain of sialic acids alters the kinetics of a glycosylated potassium channel Kv3.1. FEBS Lett 585: 3322-3327.
20. Dennis JW, Lau KS, Demetriou M, Nabi IR, (2009) Adaptive regulation at the cell surface by N-glycosylation. Traffic 10: 1569-1578.
21. Lau KS, Partridge EA, Grigorian A, Silvescu CI, Reinhold VN, et al. (2007) Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. Cell 129: 123-134.
22. Patnaik SK, Potvin B, Carlsson S, Sturm D, Leffler H, et al. (2006) Complex N-glycans are the major ligands for galectin-1,-3, and-8 on Chinese hamster ovary cells. Glycobiology 16: 305-317.
23. Liwosz A, Lei T, Kukuruzinska MA, (2006) N-glycosylation affects the molecular organization and stability of E-cadherin junctions. J Biol Chem 281: 23138-23149.
24. Yoshimura M, Ihara Y, Matsuzawa Y, Taniguchi N, (1996) Aberrant glycosylation of E-cadherin enhances cell-cell binding to suppress metastasis. J Biol Chem 271: 13811-13815.
25. Granovsky M, Fata J, Pawling J, Muller WJ, Khokha R, et al. (2000) Suppression of tumor growth and metastasis in Mgat5-deficient mice. Nat Med 6: 306-312.
26. Beheshti Zavareh R, Sukhai MA, Hurren R, Gronda M, Wang X, et al. (2012) Suppression of cancer progression by MGAT1 shRNA knockdown. PLoS One 7: e43721.
27. Paredes J, Figueiredo J, Albergaria A, Oliveira P, Carvalho J, et al. (2012) Epithelial E- and P-cadherins: Role and clinical significance in cancer. Biochim Biophys Acta 1826: 297-311.
28. Pinho SS, Seruca R, Gartner F, Yamaguchi Y, Gu J, et al. (2011) Modulation of E-cadherin function and dysfunction by N-glycosylation. Cell Mol Life Sci 68: 1011-1020.
29. Ousingsawat J, Spitzner M, Puntheeranurak S, Terracciano L, Tornillo L, et al. (2007) Expression of voltage-gated potassium channels in human and mouse colonic carcinoma. Clin Cancer Res 13: 824-831.