Phospholipase C-γ2 via p38 and ERK1/2 MAP kinase mediates diperoxovanadate-asparagine induced human platelet aggregation and sCD40L release

Redox Report

Volumn 18, Issue 5, 2013, Pages 174-185

  Misra, Ankita ^a   Srivastava, Smriti ^a   Ankireddy, Seshadri Reddy ^b   Islam, Nashreen S ^b   Chandra, Tulika ^c   Kumar, Ashutosh ^c   Barthwal, Manoj Kumar ^a   Dikshit, Madhu ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b TEZPUR UNIVERSITY   (India)

^c KING GEORGE'S MEDICAL UNIVERSITY   (India)

Author keywords

Diperoxovanadate asparagine; Phospholipase C 2; Platelet aggregation; Reactive oxygen species; Soluble CD40L; Thromboxane A2

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLSALICYLIC ACID; ADENOSINE TRIPHOSPHATE; ASPARAGINE DERIVATIVE; CD40 LIGAND; DIPEROXOVANADATE ASPARAGINE; GLYCOPROTEIN IIB; GLYCOPROTEIN IIBIIIA; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXY RADICAL; PHOSPHOLIPASE C GAMMA2; THROMBOXANE B2; UNCLASSIFIED DRUG; VANADIC ACID;

ARTICLE; CALCIUM MOBILIZATION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THROMBOCYTE AGGREGATION;

ASPARAGINE; CD40 LIGAND; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PEROXIDES; PHOSPHOLIPASE C GAMMA; PLATELET AGGREGATION; SIGNAL TRANSDUCTION; VANADATES;

EID: 84883641199     PISSN: 13510002     EISSN: 17432928     Source Type: Journal    
DOI: 10.1179/1351000213Y.0000000057     Document Type: Article

References (41)

1. Violi F, Pignatelli P. Platelet oxidative stress and thrombosis. Thromb Res 2012;129(3):378-81.
2. Iuliano L, Colavita AR, Leo R, Pratico D, Violi F. Oxygen free radicals and platelet activation. Free Radic Biol Med 1997;22(6): 999-1006.
3. Sill JC, Proper JA, Johnson ME, Uhl CB, Katusic ZS. Reactive oxygen species and human platelet GP IIb/IIIa receptor activation. Platelets 2007;18(8):613-9.
4. Leoncini G, Maresca M, Colao C. Oxidative metabolism of human platelets. Biochem Int 1991;25(4):647-55.
5. Maresca M, Colao C, Leoncini G. Generation of hydrogen peroxide in resting and activated platelets. Cell Biochem Funct 1992;10(2):79-85.
6. Pignatelli P, Pulcinelli FM, Lenti L, Gazzaniga PP, Violi F. Hydrogen peroxide is involved in collagen-induced platelet activation. Blood 1998;91(2):484-90.
7. Bakdash N, Williams MS. Spatially distinct production of reactive oxygen species regulates platelet activation. Free Radic Biol Med 2008;45(2):158-66.
8. Sobotkova A, Masova-Chrastinova L, Suttnar J, Stikarova J, Majek P, Reicheltova Z, et al. Antioxidants change platelet responses to various stimulating events. Free Radic Biol Med 2009;47(12):1707-14.
9. Rhee SG. Cell signaling. H2O2, a necessary evil for cell signaling. Science 2006;312(5782):1882-3.
10. Blake RA, Walker TR, Watson SP. Activation of human platelets by peroxovanadate is associated with tyrosine phosphorylation of phospholipase C gamma and formation of inositol phosphates. Biochem J 1993;290(Pt 2):471-5.
11. Irani K, Pham Y, Coleman LD, Roos C, Cooke GE, Miodovnik A, et al. Priming of platelet alphaIIbbeta3 by oxidants is associated with tyrosine phosphorylation of beta3. Arterioscler Thromb Vasc Biol 1998;18(11):1698-706.
12. Ravishankar HN, Rao AV, Ramasarma T. Catalase degrades diperoxovanadate and releases oxygen. Arch Biochem Biophys 1995;321(2):477-84.
13. Rao AV, Ravishankar HN, Ramasarma T. Diperoxovanadate participates in peroxidation reactions of H2O2 in presence of abundant catalase. Biochim Biophys Acta 1998;1381(2): 249-55.
14. Chatterjee N, Kiran S, Ram BM, Islam N, Ramasarma T, Ramakrishna G. Diperoxovanadate can substitute for H2O2 at much lower concentration in inducing features of premature cellular senescence in mouse fibroblasts (NIH3T3). Mech Ageing Dev 2011;132(5):230-9.
15. Natarajan V, Vepa S, Shamlal R, Al-Hassani M, Ramasarma T, Ravishankar HN, et al. Tyrosine kinases and calcium dependent activation of endothelial cell phospholipase D by diperoxovanadate. Mol Cell Biochem 1998;183(1-2):113-24.
16. Usatyuk PV, Fomin VP, Shi S, Garcia JG, Schaphorst K, Natarajan V. Role of Ca2+ in diperoxovanadate-induced cytoskeletal remodeling and endothelial cell barrier function. Am J Physiol Lung Cell Mol Physiol 2003;285(5):L1006-17.
17. Natarajan V, Scribner WM, Morris AJ, Roy S, Vepa S, Yang J, et al. Role of p38 MAP kinase in diperoxovanadate-induced phospholipase D activation in endothelial cells. Am J Physiol Lung Cell Mol Physiol 2001;281(2):L435-49.
18. Parinandi NL, Roy S, Shi S, Cummings RJ, Morris AJ, Garcia JG, et al. Role of Src kinase in diperoxovanadate-mediated activation of phospholipase D in endothelial cells. Arch Biochem Biophys 2001;396(2):231-43.
19. Khanna V, Jain M, Barthwal MK, Kalita D, Boruah JJ, Das SP, et al. Vasomodulatory effect of novel peroxovanadate compounds on rat aorta: role of rho kinase and nitric oxide/ cGMP pathway. Pharmacol Res 2011;64(3):274-82.
20. Sharma P, Barthwal MK, Dikshit M. NO synthesis and its regulation in the arachidonic-acid-stimulated rat polymorphonuclear leukocytes. Nitric Oxide 2002;7(2):119-26.
21. Prakash P, Misra A, Surin WR, Jain M, Bhatta RS, Pal R, et al. Anti-platelet effects of Curcuma oil in experimental models of myocardial ischemia-reperfusion and thrombosis. Thromb Res 2011;127(2):111-8.
22. Kim EJ, Lim KM, Kim KY, Bae ON, Noh JY, Chung SM, et al. Doxorubicin-induced platelet cytotoxicity: a new contributory factor for doxorubicin-mediated thrombocytopenia. J Thromb Haemost 2009;7(7):1172-83.
23. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 1995;184(1): 39-51.
24. Steele BM, Harper MT, Macaulay IC, Morrell CN, Perez- Tamayo A, Foy M, et al. Canonical Wnt signaling negatively regulates platelet function. Proc Natl Acad Sci USA 2009; 106(47):19836-41.
25. Jobe SM, Wilson KM, Leo L, Raimondi A, Molkentin JD, Lentz SR, et al. Critical role for the mitochondrial permeability transition pore and cyclophilin D in platelet activation and thrombosis. Blood 2008;111(3):1257-65.
26. Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260(6):3440-50.
27. Leoncini G, Bruzzese D, Signorello MG. A role for PLCgamma2 in platelet activation by homocysteine. J Cell Biochem 2007;100(5):1255-65.
28. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227(5259): 680-5.
29. Pignatelli P, Sanguigni V, Lenti L, Loffredo L, Carnevale R, Sorge R, et al. Oxidative stress-mediated platelet CD40 ligand upregulation in patients with hypercholesterolemia: effect of atorvastatin. J Thromb Haemost 2007;5(6):1170-8.
30. McNicol A, Robertson C, Gerrard JM. Vanadate activates platelets by enhancing arachidonic acid release. Blood 1993;81(9): 2329-38.
31. Tang WH, Stitham J, Gleim S, Di Febbo C, Porreca E, Fava C, et al. Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane. J Clin Invest 2011;121(11):4462-76.
32. Enomoto Y, Adachi S, Matsushima-Nishiwaki R, Doi T, Niwa M, Akamatsu S, et al. Thromboxane A(2) promotes soluble CD40 ligand release from human platelets. Atherosclerosis 2010;209(2):415-21.
33. Santilli F, Davi G, Consoli A, Cipollone F, Mezzetti A, Falco A, et al. Thromboxane-dependent CD40 ligand release in type 2 diabetes mellitus. J Am Coll Cardiol 2006;47(2):391-7.
34. Caccese D, Pratico D, Ghiselli A, Natoli S, Pignatelli P, Sanguigni V, et al. Superoxide anion and hydroxyl radical release by collagen-induced platelet aggregation-role of arachidonic acid metabolism. Thromb Haemost 2000;83(3):485-90.
35. Lee SB, Rao AK, Lee KH, Yang X, Bae YS, Rhee SG. Decreased expression of phospholipase C-beta 2 isozyme in human platelets with impaired function. Blood 1996;88(5): 1684-91.
36. Rosado JA, Redondo PC, Salido GM, Gomez-Arteta E, Sage SO, Pariente JA. Hydrogen peroxide generation induces pp60src activation in human platelets: evidence for the involvement of this pathway in store-mediated calcium entry. J Biol Chem 2004;279(3):1665-75.
37. Redondo PC, Salido GM, Rosado JA, Pariente JA. Effect of hydrogen peroxide on Ca2+ mobilisation in human platelets through sulphydryl oxidation dependent and independent mechanisms. Biochem Pharmacol 2004;67(3):491-502.
38. Coulon L, Calzada C, Moulin P, Vericel E, Lagarde M. Activation of p38 mitogen-activated protein kinase/cytosolic phospholipase A2 cascade in hydroperoxide-stressed platelets. Free Radic Biol Med 2003;35(6):616-25.
39. Henn V, Slupsky JR, Grafe M, Anagnostopoulos I, Forster R, Muller-Berghaus G, et al. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature 1998;391(6667):591-4.
40. Pignatelli P, Sanguigni V, Lenti L, Ferro D, Finocchi A, Rossi P, et al. gp91phox-dependent expression of platelet CD40 ligand. Circulation 2004;110(10):1326-9.
41. Furman MI, Krueger LA, Linden MD, Barnard MR, Frelinger AL, III, Michelson AD. Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization. J Am Coll Cardiol 2004;43(12):2319-25.