Mismatch repair deficiency screening via immunohistochemical staining in young asians with colorectal cancers

World Journal of Surgery

Volumn 37, Issue 10, 2013, Pages 2468-2475

  Chew, Min Hoe ^a   Koh, Poh Koon ^a   Tan, Melinda ^b   Lim, Kiat Hon ^c   Carol, Loi ^a   Tang, Choong Leong ^a  

^a Singapore General Hospital Outram Road ^*  (Singapore)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

^c SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PMS2 PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN MSH2; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR MARKER;

ADULT; AGE; ARTICLE; ASIAN; EARLY DIAGNOSIS; ENZYMOLOGY; ETHNOLOGY; EVALUATION STUDY; FEMALE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METHODOLOGY; MIDDLE AGED; RETROSPECTIVE STUDY; SINGAPORE; STATISTICAL MODEL; ASIAN CONTINENTAL ANCESTRY GROUP; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DEFICIENCY; PROCEDURES;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; ADULT; AGE FACTORS; ASIAN CONTINENTAL ANCESTRY GROUP; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; EARLY DETECTION OF CANCER; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LOGISTIC MODELS; MALE; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; RETROSPECTIVE STUDIES; SINGAPORE; TUMOR MARKERS, BIOLOGICAL;

EID: 84883554909     PISSN: 03642313     EISSN: 14322323     Source Type: Journal    
DOI: 10.1007/s00268-013-2134-2     Document Type: Article

References (21)

1. Lamberti C, Mangold E, Pagenstecher C et al (2006) Frequency of hereditary non-polyposis colorectal cancer among unselected patients with colorectal cancer in Germany. Digestion 74:58-67
2. Pinol V, Castells A, Andreu M, The Gastrointestinal Oncology Group of the Spanish Gastroenterological Association et al (2005) Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer. JAMA 293:1986-1994
3. Aaltonen LA, Salovaara R, Kristo P et al (1998) Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med 338:1481-1487
4. Watson P, Riley B (2005) The tumor spectrum in the Lynch syndrome. Fam Cancer 4:245-248
5. Woods MO, Hyde AJ, Curtis FK et al (2005) High frequency of hereditary colorectal cancer in Newfoundland likely involves novel susceptibility genes. Clin Cancer Res 11:6853-6861
6. Aaltonen LA, Peltomaki P, Mecklin JP et al (1994) Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res 54:1645-1648
7. Palomaki GE, McClain MR, Melillo S et al (2009) EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome. Genet Med 11:42-65
8. Boland CR, Koi M, Chang DK et al (2008) The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside. Fam Cancer 7:1-52
9. Fishel R, Lescoe MK, Rao MR et al (1994) The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 77:167
10. Wang XL, Yuan Y, Zhang SZ et al (2006) Clinical and genetic characteristics of Chinese hereditary nonpolyposis colorectal cancer families. World J Gastroenterol 12:4074-4077
11. Chew MH, Koh PK, Ng KH et al (2008) Phenotypic characteristics of hereditary non-polyposis colorectal cancer by the Amsterdam criteria: an Asian perspective. ANZ J Surg 78:556-560
12. Goh HS, Wong J (1992) The Singapore Polyposis Registry. Ann Acad Med Singapore 21:290-293
13. Edge SB, Byrd DR, Compton CC et al (2009) AJCC Cancer Staging Manual, 7th edn. Springer, New York
14. Vasen HF, Watson P, Mecklin JP et al (1999) New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology 116:1453-1456
15. Vasen HF, Mecklin JP, Khan PM et al (1994) The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC). Anticancer Res 14:1661-1664
16. Rodriguez-Bigas MA, Boland CR, Hamilton SR et al (1997) A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines. J Natl Cancer Inst 89:1758-1762
17. Kievit W, de Bruin JH, Adang EM et al (2004) Current clinical selection strategies for identification of hereditary non-polyposis colorectal cancer families are inadequate: a meta-analysis. Clin Genet 65:308-316
18. Chappelle A, Hampel H (2010) Clinical relevance of microsatellite instability in colorectal cancer. J Clin Oncol 28:3380-3387
19. Chaves P, Cruz C, Lage P et al (2000) Immunohistochemical detection of mismatch repair gene proteins as a useful tool for the identification of colorectal carcinoma with the mutator phenotype. J Pathol 191:355-360
20. Cawkwell L, Gray S, Murgatroyd H et al (1999) Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair. Gut 45:409-415
21. Yap HL, Chieng WS, Lim JR et al (2008) Recurring MLH1 deleterious mutations in unrelated Chinese Lynch syndrome families in Singapore. Fam Cancer 8:85-94