ß-catenin, Cox-2 and p53 immunostaining in colorectal adenomas to predict recurrence after endoscopic polypectomy

International Journal of Colorectal Disease

Volumn 28, Issue 8, 2013, Pages 1091-1098

  Brand, Linda ^a   Munding, Johanna ^b   Pox, Christian P ^a   Ziebarth, Wibke ^b   Reiser, Markus ^c   Hüppe, Dietrich ^e   Schmiegel, Wolff ^a,b,d   Reinacher Schick, Anke ^f   Tannapfel, Andrea ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c Paracelsus Klinik Marl   (Germany)

^d RUHR UNIVERSITY BOCHUM   (Germany)

^e Clinic for Gastroenterology and Endoscopy   (Germany)

^f ST JOSEF HOSPITAL   (Germany)

Author keywords

Adenoma recurrence; Colorectal adenoma; Cyclooxygenase 2; p53 mutation

Indexed keywords

BETA CATENIN; CYCLOOXYGENASE 2; PROTEIN P53;

ACCURACY; ADULT; ARTICLE; CANCER RECURRENCE; CANCER RISK; COLORECTAL ADENOMA; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; ENDOSCOPIC POLYPECTOMY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY (TOPIC); OUTCOME ASSESSMENT; POSTOPERATIVE PERIOD; PRACTICE GUIDELINE; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SENSITIVITY ANALYSIS; TISSUE CHARACTERIZATION; TUMOR VOLUME;

EID: 84883554738     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-013-1667-z     Document Type: Article

References (23)

1. Vogelstein B, Fearon ER, Hamilton SR et al (1988) Genetic alterations during colorectal-tumor development. N Engl J Med 319(9):525-532
2. Polakis P (1999) The oncogenic activation of beta-catenin. Curr Opin Genet Dev 9(1):15-21 (Pubitemid 29080382)
3. Araki Y, Okamura S, Hussain SP et al (2003) Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways. Cancer Res 63(3):728-734 (Pubitemid 36158154)
4. Morrin M, Kelly M, Barrett N et al (1994) Mutations of Ki-ras and p53 genes in colorectal cancer and their prognostic significance. Gut 35:1627-1631 (Pubitemid 24339267)
5. Poller DN, Hutchings CE, Galea M et al (1992) p53 protein expression in human breast carcinoma: relationship to expression of epidermal growth factor receptor, c-erbB-2 protein overexpression, and oestrogen receptor. Br J Cancer 66(3):583-588
6. Reiter RE, Anglard P, Liu S et al (1993) Chromosome 17p deletions and p53 mutations in renal cell carcinoma. Cancer Res 53(13):3092-3097 (Pubitemid 23210318)
7. Winawer SJ, Zauber AG, Ho MN et al (1993) Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N Engl J Med 329(27):1977-1981 (Pubitemid 24015040)
8. Lieberman DA, Holub J, Eisen G et al (2005) Utilization of colonoscopy in the United States: results from a national consortium. Gastrointest Endosc 62(6):875-883 (Pubitemid 41654422)
9. Bonithon-Kopp C, Piard F, Fenger C et al (2004) Colorectal adenoma characteristics as predictors of recurrence. Dis Colon Rectum 47(3):323-333 (Pubitemid 38280584)
10. Ji JS, Choi KY, Lee WC et al (2004) Endoscopic and histopathologic predictors of recurrence of colorectal adenoma on lowering the miss rate. Korean J Intern Med 24(3):196-202
11. Winawer SJ, Zauber AG, Fletcher RH et al (2006) Guidelines for colonoscopy surveillance after polypectomy: a consensus update by US Multi-society Task Force on Colorectal Cancer and the American Cancer Society. CA Cancer J Clin 56(3):143-159 (Pubitemid 43847925)
12. Schmiegel W, Pox CP, Reiser M (2004) Effect of 5-aminosalicylate (5-ASA) on colorectal adenoma recurrence. Gastroenterology 126(Supplement 2):A452
13. Takahashi M, Fukuda K, Sugimura T et al (1998) ß-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res 58:42-46 (Pubitemid 28027714)
14. Wong SC, Lo ES, Lee KC et al (2004) Prognostic and diagnostic significance of beta-catenin nuclear immunostaining in colorectal cancer. Clin Cancer Res 10(4):1401-1408 (Pubitemid 38365235)
15. Elder DJ, Baker JA, Banu NA et al (2002) Human colorectal adenomas demonstrate a size-dependent increase in epithelial cyclooxygenase-2 expression. J Pathol 198(4):428-434 (Pubitemid 35446995)
16. Boccuzzi A, Terzolo M, Leonardo E et al (1995) High frequency of p53 expression in colo-rectal adenomatous polyps. Anticancer Res 15(4):1407-1410
17. Valizadeh A, Karayiannakis AJ, el-Hariry I et al (1997) Expression of E-cadherin-associated molecules (alpha-, beta-, and gamma-catenins and p120) in colorectal polyps. Am J Pathol 150(6):1977-1984 (Pubitemid 27233071)
18. Sousa WA, Rodrigues LV, Silva RG Jr et al (2012) Immunohistochemical evaluation of p53 and Ki-67 proteins in colorectal adenomas. Arq Gastroenterol 49((1):35-40
19. Winawer S, Fletcher R, Rex D et al (2003) Colorectal cancer screening and surveillance: clinical guidelines and rationale - update based on new evidence. Gastroenterology 124(2):544-560 (Pubitemid 36169269)
20. Schmiegel W, Reinacher-Schick A, Arnold D et al (2008) Update S3 - guideline "colorectal cancer" 2008. Z Gastroenterol 46(8):799-840
21. Chung SJ, Kim YS, Yang SY et al (2011) Five-year risk for advanced colorectal neoplasia after initial colonoscopy according to the baseline risk stratification: a prospective study in 2452 asymptomatic Koreans. Gut 60(11):1537-1543
22. Martínez ME, Sampliner R, Marshall JR et al (2001) Adenoma characteristics as risk factors for recurrence of advanced adenomas. Gastroenterology 120(5):1077-1083 (Pubitemid 32246661)
23. Martínez ME, Baron JA, Lieberman DA et al (2009) A pooled analysis of advanced colorectal neoplasia diagnoses after colonoscopic polypectomy. Gastroenterology 136(3):832-841