Four-membered heterocycles-containing 4-anilino-quinazoline derivatives as epidermal growth factor receptor (EGFR) kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 19, 2013, Pages 5385-5388

  Zhao, Feng ^a   Lin, Zhaohu ^a   Wang, Feng ^a   Zhao, Weili ^a   Dong, Xiaochun ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Anilinoquinazolines; Anti tumor agents; EGFR inhibitors; Four membered heterocycles

Indexed keywords

4 ANILINO QUINAZOLINE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; GEFITINIB; QUINAZOLINE DERIVATIVE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SOLUBILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CANCER; SUBSTITUTION REACTION;

ANILINOQUINAZOLINES; ANTI-TUMOR AGENTS; EGFR INHIBITORS; FOUR-MEMBERED HETEROCYCLES;

AZA COMPOUNDS; AZETIDINES; CELL LINE, TUMOR; ENZYME ACTIVATION; HETEROCYCLIC COMPOUNDS; HUMANS; MOLECULAR STRUCTURE; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84883490371     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.07.049     Document Type: Article

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