Crystalline calcium alendronate obtained by octacalcium phosphate digestion: A new chance for local treatment of bone loss diseases?

Advanced Materials

Volumn 25, Issue 33, 2013, Pages 4605-4611

  Boanini, Elisa ^a   Torricelli, Paola ^b   Gazzano, Massimo ^c   Fini, Milena ^b   Bigi, Adriana ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^c CNR   (Italy)

Author keywords

bisphosphonate; in vitro co cultures; octacalcium phosphate

Indexed keywords

ALENDRONATE; BISPHOSPHONATES; BONE LOSS; CALCIUM IONS; CO-CULTURES; OCTACALCIUM PHOSPHATE; OSTEOBLAST DIFFERENTIATION; OSTEOCLAST PROLIFERATION;

CALCIUM; CRYSTALLINE MATERIALS;

CALCIUM PHOSPHATE;

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CALCIUM PHOSPHATE;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; CYTOLOGY; DRUG EFFECT; HUMAN; IN VITRO CO-CULTURES; METABOLISM; OSTEOBLAST; OSTEOLYSIS; PARTICLE SIZE; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY;

BISPHOSPHONATE; IN VITRO CO-CULTURES; OCTACALCIUM PHOSPHATE;

ALENDRONATE; BONE RESORPTION; CALCIUM; CALCIUM PHOSPHATES; CELL DIFFERENTIATION; CELL PROLIFERATION; CRYSTALLIZATION; HUMANS; MODELS, MOLECULAR; OSTEOBLASTS; PARTICLE SIZE; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PROPERTIES;

EID: 84883487818     PISSN: 09359648     EISSN: 15214095     Source Type: Journal    
DOI: 10.1002/adma.201301129     Document Type: Article

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