Investigation of alendronate-doped apatitic cements as a potential technology for the prevention of osteoporotic hip fractures: Critical influence of the drug introduction mode on the in vitro cement properties

Acta Biomaterialia

Volumn 7, Issue 2, 2011, Pages 759-770

  Schnitzler, Verena ^a   Fayon, Franck ^b   Despas, Christelle ^c   Khairoun, Ibrahim ^d   Mellier, Charlotte ^a   Rouillon, Thierry ^d   Massiot, Dominique ^b   Walcarius, Alain ^c   Janvier, Pascal ^d   Gauthier, Olivier ^d   Montavon, Gilles ^e   Bouler, Jean Michel ^d   Bujoli, Bruno ^d  

^a Pôle d'Activités d'Aix en Provence   (France)

^b CNRS   (France)

^c Laboratoire de Chimie Physique et Microbiologie pour l'Environnement   (France)

^d UNIVERSITÉ DE NANTES   (France)

^e SUBATECH   (France)

Author keywords

Biomedical applications; Bisphosphonates; Calcium phosphate cements; Drug delivery; Osteoporosis

Indexed keywords

BONE CEMENT; CALCIUM PHOSPHATE; CONTROLLED DRUG DELIVERY; MEDICAL APPLICATIONS; SETTING; TARGETED DRUG DELIVERY;

ALENDRONATE; APATITIC CEMENTS; BIOMEDICAL APPLICATIONS; BISPHOSPHONATES; CALCIUM PHOSPHATE CEMENT; CEMENT PROPERTIES; IN-VITRO; OSTEOPOROTIC; OSTEOPOROTIC HIP FRACTURES; POTENTIAL TECHNOLOGIES;

CEMENTS;

ALENDRONIC ACID; BONE CEMENT; CALCIUM PHOSPHATE; CALCIUM PHOSPHATE DIBASIC; HYDROXYAPATITE;

ARTICLE; CHEMICAL REACTION; COMPRESSIVE STRENGTH; DRUG RELEASE; FRAGILITY FRACTURE; HIP FRACTURE; IMPEDANCE; PRIORITY JOURNAL; REACTION TIME; SURFACE PROPERTY;

EID: 78650578748     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.09.017     Document Type: Article

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