-
1
-
-
79952638264
-
Cellular decision making and biological noise: From microbes to mammals
-
Balazsi,G., van Oudenaarden,A. and Collins,J.J. (2011) Cellular decision making and biological noise: from microbes to mammals. Cell, 144, 910-925
-
(2011)
Cell
, vol.144
, pp. 910-925
-
-
Balazsi, G.1
Van Oudenaarden, A.2
Collins, J.J.3
-
2
-
-
0037119587
-
Stochastic gene expression in a single cell
-
Elowitz,M.B., Levine,A.J., Siggia,E.D. and Swain,P.S. (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186
-
(2002)
Science
, vol.297
, pp. 1183-1186
-
-
Elowitz, M.B.1
Levine, A.J.2
Siggia, E.D.3
Swain, P.S.4
-
3
-
-
33646540711
-
Predicting stochastic gene expression dynamics in single cells
-
Mettetal,J.T., Muzzey,D., Pedraza,J.M., Ozbudak,E.M. and van Oudenaarden,A. (2006) Predicting stochastic gene expression dynamics in single cells. Proc. Natl Acad. Sci. USA, 103, 7304-7309
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 7304-7309
-
-
Mettetal, J.T.1
Muzzey, D.2
Pedraza, J.M.3
Ozbudak, E.M.4
Van Oudenaarden, A.5
-
4
-
-
53549123008
-
Nature, nurture, or chance: Stochastic gene expression and its consequences
-
Raj,A. and van Oudenaarden,A. (2008) Nature, nurture, or chance: stochastic gene expression and its consequences. Cell, 135, 216-226
-
(2008)
Cell
, vol.135
, pp. 216-226
-
-
Raj, A.1
Van Oudenaarden, A.2
-
5
-
-
67650319009
-
Single-molecule approaches to stochastic gene expression
-
Raj,A. and van Oudenaarden,A. (2009) Single-molecule approaches to stochastic gene expression. Annu. Rev. Biophys., 38, 255-270
-
(2009)
Annu. Rev. Biophys
, vol.38
, pp. 255-270
-
-
Raj, A.1
Van Oudenaarden, A.2
-
6
-
-
0032562720
-
Visualization of single RNA transcripts in situ
-
Femino,A.M., Fay,F.S., Fogarty,K. and Singer,R.H. (1998) Visualization of single RNA transcripts in situ. Science, 280, 585-590
-
(1998)
Science
, vol.280
, pp. 585-590
-
-
Femino, A.M.1
Fay, F.S.2
Fogarty, K.3
Singer, R.H.4
-
7
-
-
53349161901
-
Imaging individual mRNA molecules using multiple singly labeled probes
-
Raj,A., van den Bogaard,P., Rifkin,S.A., van Oudenaarden,A. and Tyagi,S. (2008) Imaging individual mRNA molecules using multiple singly labeled probes. Nat. Methods, 5, 877-879
-
(2008)
Nat. Methods
, vol.5
, pp. 877-879
-
-
Raj, A.1
Van Den Bogaard, P.2
Rifkin, S.A.3
Van Oudenaarden, A.4
Tyagi, S.5
-
8
-
-
33748994704
-
Stochastic mRNA synthesis in mammalian cells
-
Raj,A., Peskin,C.S., Tranchina,D., Vargas,D.Y. and Tyagi,S. (2006) Stochastic mRNA synthesis in mammalian cells. PLoS Biol., 4, e309
-
(2006)
PLoS Biol
, vol.4
-
-
Raj, A.1
Peskin, C.S.2
Tranchina, D.3
Vargas, D.Y.4
Tyagi, S.5
-
9
-
-
77249114260
-
Variability in gene expression underlies incomplete penetrance
-
Raj,A., Rifkin,S.A., Andersen,E. and van Oudenaarden,A. (2010) Variability in gene expression underlies incomplete penetrance. Nature, 463, 913-918
-
(2010)
Nature
, vol.463
, pp. 913-918
-
-
Raj, A.1
Rifkin, S.A.2
Andersen, E.3
Van Oudenaarden, A.4
-
10
-
-
84455200588
-
Single-molecule mRNA decay measurements reveal promoter-regulated mRNA stability in yeast
-
Trcek,T., Larson,D.R., Moldon,A., Query,C.C. and Singer,R.H. (2011) Single-molecule mRNA decay measurements reveal promoter-regulated mRNA stability in yeast. Cell, 147, 1484-1497
-
(2011)
Cell
, vol.147
, pp. 1484-1497
-
-
Trcek, T.1
Larson, D.R.2
Moldon, A.3
Query, C.C.4
Singer, R.H.5
-
11
-
-
33646591544
-
Transcriptional pulsing of a developmental gene
-
Chubb,J.R., Trcek,T., Shenoy,S.M. and Singer,R.H. (2006) Transcriptional pulsing of a developmental gene. Curr. Biol., 16, 1018-1025
-
(2006)
Curr. Biol
, vol.16
, pp. 1018-1025
-
-
Chubb, J.R.1
Trcek, T.2
Shenoy, S.M.3
Singer, R.H.4
-
12
-
-
28944434119
-
Realtime kinetics of gene activity in individual bacteria
-
Golding,I., Paulsson,J., Zawilski,S.M. and Cox,E.C. (2005) Realtime kinetics of gene activity in individual bacteria. Cell, 123, 1025-1036
-
(2005)
Cell
, vol.123
, pp. 1025-1036
-
-
Golding, I.1
Paulsson, J.2
Zawilski, S.M.3
Cox, E.C.4
-
13
-
-
79955488304
-
Dynamic analysis of stochastic transcription cycles
-
Harper,C.V., Finkenstadt,B., Woodcock,D.J., Friedrichsen,S., Semprini,S., Ashall,L., Spiller,D.G., Mullins,J.J., Rand,D.A., Davis,J.R. et al. (2011) Dynamic analysis of stochastic transcription cycles. PLoS Biol., 9, e1000607
-
(2011)
PLoS Biol
, vol.9
-
-
Harper, C.V.1
Finkenstadt, B.2
Woodcock, D.J.3
Friedrichsen, S.4
Semprini, S.5
Ashall, L.6
Spiller, D.G.7
Mullins, J.J.8
Rand, D.A.9
Davis, J.R.10
-
14
-
-
71649113974
-
Visualization of individual scr mrnas during drosophila embryogenesis yields evidence for transcriptional bursting
-
Pare,A., Lemons,D., Kosman,D., Beaver,W., Freund,Y. and McGinnis,W. (2009) Visualization of individual Scr mRNAs during Drosophila embryogenesis yields evidence for transcriptional bursting. Curr. Biol., 19, 2037-2042
-
(2009)
Curr. Biol
, vol.19
, pp. 2037-2042
-
-
Pare, A.1
Lemons, D.2
Kosman, D.3
Beaver, W.4
Freund, Y.5
McGinnis, W.6
-
15
-
-
79955381895
-
Mammalian genes are transcribed with widely different bursting kinetics
-
Suter,D.M., Molina,N., Gatfield,D., Schneider,K., Schibler,U. and Naef,F. (2011) Mammalian genes are transcribed with widely different bursting kinetics. Science, 332, 472-474
-
(2011)
Science
, vol.332
, pp. 472-474
-
-
Suter, D.M.1
Molina, N.2
Gatfield, D.3
Schneider, K.4
Schibler, U.5
Naef, F.6
-
16
-
-
0021066596
-
Localization of actin messenger RNA during early ascidian development
-
Jeffery,W.R., Tomlinson,C.R. and Brodeur,R.D. (1983) Localization of actin messenger RNA during early ascidian development. Dev. Biol., 99, 408-417
-
(1983)
Dev. Biol
, vol.99
, pp. 408-417
-
-
Jeffery, W.R.1
Tomlinson, C.R.2
Brodeur, R.D.3
-
17
-
-
34848918150
-
Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function
-
Lecuyer,E., Yoshida,H., Parthasarathy,N., Alm,C., Babak,T., Cerovina,T., Hughes,T.R., Tomancak,P. and Krause,H.M. (2007) Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell, 131, 174-187
-
(2007)
Cell
, vol.131
, pp. 174-187
-
-
Lecuyer, E.1
Yoshida, H.2
Parthasarathy, N.3
Alm, C.4
Babak, T.5
Cerovina, T.6
Hughes, T.R.7
Tomancak, P.8
Krause, H.M.9
-
18
-
-
66249103703
-
RNA granules: Posttranscriptional and epigenetic modulators of gene expression
-
Anderson,P. and Kedersha,N. (2009) RNA granules: posttranscriptional and epigenetic modulators of gene expression. Nat. Rev. Mol. Cell Biol., 10, 430-436
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 430-436
-
-
Anderson, P.1
Kedersha, N.2
-
19
-
-
0031983834
-
Multicolor molecular beacons for allele discrimination
-
Tyagi,S., Bratu,D.P. and Kramer,F.R. (1998) Multicolor molecular beacons for allele discrimination. Nat. Biotechnol., 16, 49-53
-
(1998)
Nat. Biotechnol
, vol.16
, pp. 49-53
-
-
Tyagi, S.1
Bratu, D.P.2
Kramer, F.R.3
-
20
-
-
0029670262
-
Molecular beacons: Probes that fluoresce upon hybridization
-
Tyagi,S. and Kramer,F.R. (1996) Molecular beacons: probes that fluoresce upon hybridization. Nat. Biotechnol., 14, 303-308
-
(1996)
Nat. Biotechnol
, vol.14
, pp. 303-308
-
-
Tyagi, S.1
Kramer, F.R.2
-
21
-
-
0344824383
-
Visualizing the distribution and transport of mRNAs in living cells
-
Bratu,D.P., Cha,B.J., Mhlanga,M.M., Kramer,F.R. and Tyagi,S. (2003) Visualizing the distribution and transport of mRNAs in living cells. Proc. Natl Acad. Sci. USA, 100, 13308-13313
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 13308-13313
-
-
Bratu, D.P.1
Cha, B.J.2
Mhlanga, M.M.3
Kramer, F.R.4
Tyagi, S.5
-
22
-
-
27744463933
-
Stochasticity of manganese superoxide dismutase mRNA expression in breast carcinoma cells by molecular beacon imaging
-
Drake,T.J., Medley,C.D., Sen,A., Rogers,R.J. and Tan,W. (2005) Stochasticity of manganese superoxide dismutase mRNA expression in breast carcinoma cells by molecular beacon imaging. Chembiochem., 6, 2041-2047
-
(2005)
Chembiochem
, vol.6
, pp. 2041-2047
-
-
Drake, T.J.1
Medley, C.D.2
Sen, A.3
Rogers, R.J.4
Tan, W.5
-
23
-
-
56749169576
-
NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells
-
Nitin,N. and Bao,G. (2008) NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells. Bioconjug. Chem., 19, 2205-2211
-
(2008)
Bioconjug. Chem
, vol.19
, pp. 2205-2211
-
-
Nitin, N.1
Bao, G.2
-
24
-
-
65849507275
-
Simultaneous detection of mRNA and protein stem cell markers in live cells
-
Rhee,W.J. and Bao,G. (2009) Simultaneous detection of mRNA and protein stem cell markers in live cells. BMC Biotechnol., 9, 30
-
(2009)
BMC Biotechnol
, vol.9
, pp. 30
-
-
Rhee, W.J.1
Bao, G.2
-
25
-
-
34548724424
-
Avoiding falsepositive signals with nuclease-vulnerable molecular beacons in single living cells
-
Chen,A.K., Behlke,M.A. and Tsourkas,A. (2007) Avoiding falsepositive signals with nuclease-vulnerable molecular beacons in single living cells. Nucleic Acids Res., 35, e105
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Chen, A.K.1
Behlke, M.A.2
Tsourkas, A.3
-
26
-
-
47249136607
-
Efficient cytosolic delivery of molecular beacon conjugates and flow cytometric analysis of target RNA
-
Chen,A.K., Behlke,M.A. and Tsourkas,A. (2008) Efficient cytosolic delivery of molecular beacon conjugates and flow cytometric analysis of target RNA. Nucleic Acids Res., 36, e69
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Chen, A.K.1
Behlke, M.A.2
Tsourkas, A.3
-
27
-
-
75649136910
-
Sub-cellular trafficking and functionality of 20-O-methyl and 20-O-methylphosphorothioate molecular beacons
-
Chen,A.K., Behlke,M.A. and Tsourkas,A. (2009) Sub-cellular trafficking and functionality of 20-O-methyl and 20-O-methylphosphorothioate molecular beacons. Nucleic Acids Res., 37, e149
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Chen, A.K.1
Behlke, M.A.2
Tsourkas, A.3
-
28
-
-
17144392600
-
TRNA-linked molecular beacons for imaging mRNAs in the cytoplasm of living cells
-
Mhlanga,M.M., Vargas,D.Y., Fung,C.W., Kramer,F.R. and Tyagi,S. (2005) tRNA-linked molecular beacons for imaging mRNAs in the cytoplasm of living cells. Nucleic Acids Res., 33, 1902-1912
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 1902-1912
-
-
Mhlanga, M.M.1
Vargas, D.Y.2
Fung, C.W.3
Kramer, F.R.4
Tyagi, S.5
-
29
-
-
0002726408
-
Linear 20 omethyl rna probes for the visualization of rna in living cells
-
Molenaar,C., Marras,S.A., Slats,J.C., Truffert,J.C., Lemaitre,M., Raap,A.K., Dirks,R.W. and Tanke,H.J. (2001) Linear 20 OMethyl RNA probes for the visualization of RNA in living cells. Nucleic Acids Res., 29, E89-E89
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Molenaar, C.1
Marras, S.A.2
Slats, J.C.3
Truffert, J.C.4
Lemaitre, M.5
Raap, A.K.6
Dirks, R.W.7
Tanke, H.J.8
-
30
-
-
78649565985
-
Imaging RNA in living cells with molecular beacons: Current perspective and challenges
-
Chen,A.K. and Tsourkas,A. (2009) Imaging RNA in living cells with molecular beacons: current perspective and challenges. J. Innov. Opt. Health Sci., 2, 315-324
-
(2009)
J. Innov. Opt. Health Sci
, vol.2
, pp. 315-324
-
-
Chen, A.K.1
Tsourkas, A.2
-
31
-
-
77955788881
-
Ratiometric bimolecular beacons for the sensitive detection of RNA in single living cells
-
Chen,A.K., Davydenko,O., Behlke,M.A. and Tsourkas,A. (2010) Ratiometric bimolecular beacons for the sensitive detection of RNA in single living cells. Nucleic Acids Res., 38, e148
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Chen, A.K.1
Davydenko, O.2
Behlke, M.A.3
Tsourkas, A.4
-
32
-
-
28044451048
-
Mechanism of mRNA transport in the nucleus
-
Vargas,D.Y., Raj,A., Marras,S.A., Kramer,F.R. and Tyagi,S. (2005) Mechanism of mRNA transport in the nucleus. Proc. Natl Acad. Sci. USA, 102, 17008-17013
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 17008-17013
-
-
Vargas, D.Y.1
Raj, A.2
Marras, S.A.3
Kramer, F.R.4
Tyagi, S.5
-
33
-
-
0036798115
-
Structure-function relationships of shared-stem and conventional molecular beacons
-
Tsourkas,A., Behlke,M.A. and Bao,G. (2002) Structure-function relationships of shared-stem and conventional molecular beacons. Nucleic Acids Res., 30, 4208-4215
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 4208-4215
-
-
Tsourkas, A.1
Behlke, M.A.2
Bao, G.3
-
34
-
-
26444477373
-
Automatic tracking of individual fluorescence particles: Application to the study of chromosome dynamics IEEE Trans
-
Sage,D., Neumann,F.R., Hediger,F., Gasser,S.M. and Unser,M. (2005) Automatic tracking of individual fluorescence particles: application to the study of chromosome dynamics IEEE Trans. Image Process., 14, 1372-1383
-
(2005)
Image Process
, vol.14
, pp. 1372-1383
-
-
Sage, D.1
Neumann, F.R.2
Hediger, F.3
Gasser, S.M.4
Unser, M.5
-
35
-
-
54749105886
-
Assessing the sensitivity of commercially available fluorophores to the intracellular environment
-
Chen,A.K., Cheng,Z., Behlke,M.A. and Tsourkas,A. (2008) Assessing the sensitivity of commercially available fluorophores to the intracellular environment. Anal. Chem., 80, 7437-7444
-
(2008)
Anal. Chem
, vol.80
, pp. 7437-7444
-
-
Chen, A.K.1
Cheng, Z.2
Behlke, M.A.3
Tsourkas, A.4
-
36
-
-
0033519623
-
Localization and anchoring of mRNA in budding yeast
-
Beach,D.L., Salmon,E.D. and Bloom,K. (1999) Localization and anchoring of mRNA in budding yeast. Curr. Biol., 9, 569-578
-
(1999)
Curr. Biol
, vol.9
, pp. 569-578
-
-
Beach, D.L.1
Salmon, E.D.2
Bloom, K.3
-
37
-
-
0032185810
-
Localization of ASH1 mRNA particles in living yeast
-
Bertrand,E., Chartrand,P., Schaefer,M., Shenoy,S.M., Singer,R.H. and Long,R.M. (1998) Localization of ASH1 mRNA particles in living yeast. Mol. Cell, 2, 437-445
-
(1998)
Mol. Cell
, vol.2
, pp. 437-445
-
-
Bertrand, E.1
Chartrand, P.2
Schaefer, M.3
Shenoy, S.M.4
Singer, R.H.5
Long, R.M.6
-
38
-
-
0038376482
-
Live imaging of endogenous rna reveals a diffusion and entrapment mechanism for nanos mrna localization in drosophila
-
Forrest,K.M. and Gavis,E.R. (2003) Live imaging of endogenous RNA reveals a diffusion and entrapment mechanism for nanos mRNA localization in Drosophila. Curr. Biol., 13, 1159-1168
-
(2003)
Curr. Biol
, vol.13
, pp. 1159-1168
-
-
Forrest, K.M.1
Gavis, E.R.2
-
39
-
-
0347156907
-
Single mRNA molecules demonstrate probabilistic movement in living mammalian cells
-
Fusco,D., Accornero,N., Lavoie,B., Shenoy,S.M., Blanchard,J.M., Singer,R.H. and Bertrand,E. (2003) Single mRNA molecules demonstrate probabilistic movement in living mammalian cells. Curr. Biol., 13, 161-167
-
(2003)
Curr. Biol
, vol.13
, pp. 161-167
-
-
Fusco, D.1
Accornero, N.2
Lavoie, B.3
Shenoy, S.M.4
Blanchard, J.M.5
Singer, R.H.6
Bertrand, E.7
-
40
-
-
0034257926
-
CaMKIIalpha 30 untranslated region-directed mRNA translocation in living neurons: Visualization by GFP linkage
-
Rook,M.S., Lu,M. and Kosik,K.S. (2000) CaMKIIalpha 30 untranslated region-directed mRNA translocation in living neurons: visualization by GFP linkage. J. Neurosci., 20, 6385-6393
-
(2000)
J. Neurosci
, vol.20
, pp. 6385-6393
-
-
Rook, M.S.1
Lu, M.2
Kosik, K.S.3
-
41
-
-
33746492940
-
Localization of bicoid mRNA in late oocytes is maintained by continual active transport
-
T.T., Forrest,K.M. and Gavis,E.R. (2006) Localization of bicoid mRNA in late oocytes is maintained by continual active transport. Dev. Cell, 11, 251-262
-
(2006)
Dev. Cell
, vol.11
, pp. 251-262
-
-
Forrest, K.M.1
Gavis, E.R.2
|