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Volumn 11, Issue 37, 2013, Pages 6328-6337
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Synthesis, biological evaluation and molecular docking of novel 5-phenyl-1H-pyrazol derivatives as potential BRAFV600E inhibitors
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTI-PROLIFERATIVE ACTIVITIES;
ANTIPROLIFERATIVE ASSAYS;
BIOLOGICAL EVALUATION;
CELL-CYCLE PROGRESSION;
CELLULAR GROWTH;
DOCKING SIMULATIONS;
INHIBITORY ACTIVITY;
MOLECULAR DOCKING;
CELL CULTURE;
CELL DEATH;
UREA;
MOLECULAR GRAPHICS;
ANTINEOPLASTIC AGENT;
B RAF KINASE;
PYRAZOLE;
PYRAZOLE DERIVATIVE;
ANIMAL;
ARTICLE;
CELL LINE;
CELL PROLIFERATION;
CHEMISTRY;
DRUG ANTAGONISM;
DRUG EFFECT;
GENETICS;
HUMAN;
IC 50;
METABOLISM;
MUTATION;
QUANTITATIVE STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
X RAY CRYSTALLOGRAPHY;
ANIMALS;
ANTINEOPLASTIC AGENTS;
CELL LINE;
CELL PROLIFERATION;
CRYSTALLOGRAPHY, X-RAY;
HUMANS;
INHIBITORY CONCENTRATION 50;
MUTATION;
PROTO-ONCOGENE PROTEINS B-RAF;
PYRAZOLES;
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 84883443973
PISSN: 14770520
EISSN: None
Source Type: Journal
DOI: 10.1039/c3ob40776d Document Type: Article |
Times cited : (27)
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References (31)
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