Targeting listeria monocytogenes rpoA and rpoD genes using peptide nucleic acids

Nucleic Acid Therapeutics

Volumn 23, Issue 5, 2013, Pages 363-367

  Alajlouni, Ruba A ^a   Seleem, Mohamed N ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM CULTURE; CAENORHABDITIS ELEGANS; CLEARANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE TARGETING; GROWTH INHIBITION; LISTERIA MONOCYTOGENES; MOUSE; NONHUMAN; PRIORITY JOURNAL; RPOA GENE; RPOD GENE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CAENORHABDITIS ELEGANS; CELL LINE; CELL-PENETRATING PEPTIDES; COLONY COUNT, MICROBIAL; DNA-DIRECTED RNA POLYMERASES; DRUG CARRIERS; LISTERIA MONOCYTOGENES; MACROPHAGES; MICE; PEPTIDE NUCLEIC ACIDS; SIGMA FACTOR;

EID: 84883434852     PISSN: 21593337     EISSN: None     Source Type: Journal    
DOI: 10.1089/nat.2013.0426     Document Type: Article

References (23)

1. BAI, H., YOU, Y., YAN, H., MENG, J., XUE, X., HOU, Z., ZHOU, Y., MA, X., SANG, G., and LUO, X. (2012). Antisense inhibition of gene expression and growth in gram-negative bacteria by cell-penetrating peptide conjugates of peptide nucleic acids targeted to rpoD gene. Biomaterials 33, 659-667.
2. BUFFER, J.L., MEDEIROS, L.C., KENDALL, P., SCHROEDER, M., and SOFOS, J. (2012). Health professionals' knowledge and understanding about L. monocytogenes indicates a need for improved professional training. J. Food Protect. 75, 1310-1316.
3. DRYSELIUS, R., ASWASTI, S.K., RAJARAO, G.K., NIELSEN, P.E., and GOOD, L. (2003). The translation start codon region is sensitive to antisense PNA inhibition in Escherichia coli. Oligonucleotides 13, 427-433.
4. ERIKSSON, M., NIELSEN, P.E., and GOOD, L. (2002). Cell permeabilization and uptake of antisense peptide-peptide nucleic acid (PNA) into Escherichia coli. J. Biol. Chem. 277, 7144-7147.
5. GOH, S., BOBEREK, J.M., NAKASHIMA, N., STACH, J., and GOOD, L. (2009). Concurrent growth rate and transcript analyses reveal essential gene stringency in Escherichia coli. PLoS One 4, e6061.
6. GOOD, L., and NIELSEN, P.E. (1998a). Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA. Nat. Biotechnol. 16, 355-358.
7. GOOD, L., and NIELSEN, P.E. (1998b). Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA. Proc. Natl. Acad. Sci. U. S. A. 95, 2073-2076.
8. GOTTLIEB, C., THOMSEN, L., INGMER, H., MYGIND, P., KRISTENSEN, H.-H., and GRAM, L. (2008). Antimicrobial peptides effectively kill a broad spectrum of Listeria monocytogenes and Staphylococcus aureus strains independently of origin, sub-type, or virulence factor expression. BMC Microbiol. 8, 205.
9. HANVEY, J.C., PEFFER, N.J., BISI, J.E., THOMSON, S.A., CADILLA, R., JOSEY, J.A., RICCA, D.J., HASSMAN, C.F., BONHAM, M.A., AU, K.G., et al. (1992). Antisense and antigene properties of peptide nucleic acids. Science 258, 1481-1485.
10. HOFFMANN, S., BATZ, M.B., and MORRIS JR, J.G. (2012). Annual cost of illness and quality-adjusted life year losses in the United States due to 14 foodborne pathogens. J. Food Prot. 75, 1292-1302.
11. KULYTE, A., NEKHOTIAEVA, N., AWASTHI, S.K., and GOOD, L. (2005). Inhibition of Mycobacterium smegmatis gene expression and growth using antisense peptide nucleic acids. J. Mol. Microbiol. Biotechnol. 9, 101-109.
12. KURUPATI, P., TAN, K.S.W., KUMARASINGHE, G., and POH, C.L. (2007). Inhibition of gene expression and growth by antisense peptide nucleic acids in a multiresistant betalactamase-producing Klebsiella pneumoniae strain. Antimicrob. Agents Chemother. 51, 805-811.
13. MITJA, O., PIGRAU, C., RUIZ, I., VIDAL, X., ALMIRANTE, B., PLANES, A.M., MOLINA, I., RODRIGUEZ, D., and PAHISSA, A. (2009). Predictors of mortality and impact of aminoglycosides on outcome in listeriosis in a retrospective cohort study. J. Antimicrob. Chemother. 64, 416-423.
14. MOY, T.I., CONERY, A.L., LARKINS-FORD, J., WU, G., MAZITSCHEK, R., CASADEI, G., LEWIS, K., CARPENTER, A.E., and AUSUBEL, F.M. (2009). High-throughput screen for novel antimicrobials using a whole animal infection model. ACS Chem. Biol. 4, 527-533.
15. NEKHOTIAEVA, N., AWASTHI, S.K., NIELSEN, P.E., and GOOD, L. (2004). Inhibition of Staphylococcus aureus gene expression and growth using antisense peptide nucleic acids. Mol. Ther. 10, 652-659.
16. NIELSEN, P.E., EGHOLM, M., BERG, R.H., and BUCHARDT, O. (1991). Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science 254, 1497-1500.
17. POWELL, J.R., and AUSUBEL, F.M. (2008). Models of Caenorhabditis elegans infection by bacterial and fungal pathogens. In: Methods in Molecular Biology, vol. 415: Innate Immunity. Ewbank, J., Vivier, E., eds. (Humana Press, Inc., Totowa, New Jersey), pp. 403-427.
18. RASMUSSEN, L.C., SPERLING-PETERSEN, and H.U., MORTENSEN, K.K. (2007). Hitting bacteria at the heart of the central dogma: Sequence-specific inhibition. Microb. Cell Fact. 6, 24.
19. SCHLECH, W.F. (2000). Foodborne listeriosis. Clin. Infect. Dis. 31, 770-775.
20. SOOFI, M.A., and SELEEM, M.N. (2012). Targeting Salmonella essential genes with antisense peptide nucleic acid. Antimicrob. Agents Chemother. 12: 6407-6409.
21. STIERNAGLE, T. (2006). Maintenance of C. elegans WormBook and the c. elegans research community. www.wormbook.org/ chapters/www-strainmaintain/ strainmaintain.html
22. THOMSEN, L.E., SLUTZ, S.S., TAN, M.-W., and INGMER, H. (2006). Caenorhabditis elegans is a model host for Listeria monocytogenes. Appl. Environ. Microbiol. 72, 1700-1701.
23. YURA, T., ISHIHAMA, A. (1979). Genetics of bacterial RNA polymeras. Annu. Rev. Genet. 13, 59-97.