-
2
-
-
0035379237
-
Molecular virology of hepatitis C virus
-
Kato N, (2001) Molecular virology of hepatitis C virus. Acta Med Okayama 55: 133-159.
-
(2001)
Acta Med Okayama
, vol.55
, pp. 133-159
-
-
Kato, N.1
-
3
-
-
0025685188
-
Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis
-
Kato N, Hijikata M, Ootsuyama Y, Nakagawa M, Ohkoshi S, et al. (1990) Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci U S A 87: 9524-9528.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 9524-9528
-
-
Kato, N.1
Hijikata, M.2
Ootsuyama, Y.3
Nakagawa, M.4
Ohkoshi, S.5
-
4
-
-
35649014170
-
Interferon-based therapy of hepatitis C
-
Chevaliez S, Pawlotsky JM, (2007) Interferon-based therapy of hepatitis C. Adv Drug Deliv Rev. 59: 1222-1241.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 1222-1241
-
-
Chevaliez, S.1
Pawlotsky, J.M.2
-
5
-
-
80053339008
-
An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases
-
Ghany MG, Nelson DR, Strader DB, Thomas DL, Seeff LB, (2011) An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology 54: 1433-1444.
-
(2011)
Hepatology
, vol.54
, pp. 1433-1444
-
-
Ghany, M.G.1
Nelson, D.R.2
Strader, D.B.3
Thomas, D.L.4
Seeff, L.B.5
-
6
-
-
79959438789
-
Telaprevir for previously untreated chronic hepatitis C virus infection
-
Jacobson IM, McHutchison JG, Dusheiko G, Di Bisceglie AM, Reddy KR, et al. (2011) Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 364: 2405-2416.
-
(2011)
N Engl J Med
, vol.364
, pp. 2405-2416
-
-
Jacobson, I.M.1
McHutchison, J.G.2
Dusheiko, G.3
Di Bisceglie, A.M.4
Reddy, K.R.5
-
7
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
Poordad F, McCone J Jr, Bacon BR, Bruno S, Manns MP, et al. (2011) Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 364: 1195-1206.
-
(2011)
N Engl J Med
, vol.364
, pp. 1195-1206
-
-
Poordad, F.1
McCone Jr., J.2
Bacon, B.R.3
Bruno, S.4
Manns, M.P.5
-
8
-
-
33749360242
-
Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized study
-
Reesink HW, Zeuzem S, Weegink CJ, Forestier N, van Vliet A, et al. (2006) Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized study. Gastroenterology 131: 997-1002.
-
(2006)
Gastroenterology
, vol.131
, pp. 997-1002
-
-
Reesink, H.W.1
Zeuzem, S.2
Weegink, C.J.3
Forestier, N.4
van Vliet, A.5
-
9
-
-
73149113353
-
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients
-
Susser S, Welsch C, Wang Y, Zettler M, Domingues FS, et al. (2009) Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients. Hepatology 50: 1709-1718.
-
(2009)
Hepatology
, vol.50
, pp. 1709-1718
-
-
Susser, S.1
Welsch, C.2
Wang, Y.3
Zettler, M.4
Domingues, F.S.5
-
10
-
-
79959478969
-
Clinical practice. Chronic hepatitis C infection
-
Rosen HR, (2011) Clinical practice. Chronic hepatitis C infection. N Engl J Med 364: 2429-2438.
-
(2011)
N Engl J Med
, vol.364
, pp. 2429-2438
-
-
Rosen, H.R.1
-
11
-
-
79955103901
-
Treatment failure and resistance with direct-acting antiviral drugs against hepatitis C virus
-
Pawlotsky JM, (2011) Treatment failure and resistance with direct-acting antiviral drugs against hepatitis C virus. Hepatology 53: 1742-1751.
-
(2011)
Hepatology
, vol.53
, pp. 1742-1751
-
-
Pawlotsky, J.M.1
-
12
-
-
34447296186
-
Hepatitis C virus molecular clones and their replication capacity in vivo and in cell culture
-
Bartenschlager R, Sparacio S, (2007) Hepatitis C virus molecular clones and their replication capacity in vivo and in cell culture. Virus Res 127: 195-207.
-
(2007)
Virus Res
, vol.127
, pp. 195-207
-
-
Bartenschlager, R.1
Sparacio, S.2
-
13
-
-
16244394753
-
Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system
-
Ikeda M, Abe K, Dansako H, Nakamura T, Naka K, et al. (2005) Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system. Biochem Biophys Res Commun 329: 1350-1359.
-
(2005)
Biochem Biophys Res Commun
, vol.329
, pp. 1350-1359
-
-
Ikeda, M.1
Abe, K.2
Dansako, H.3
Nakamura, T.4
Naka, K.5
-
14
-
-
35648972113
-
Modulation of host metabolism as a target of new antivirals
-
Ikeda M, Kato N, (2007) Modulation of host metabolism as a target of new antivirals. Adv Drug Deliv Rev 59: 1277-1289.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 1277-1289
-
-
Ikeda, M.1
Kato, N.2
-
16
-
-
16244415552
-
Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha
-
Naka K, Ikeda M, Abe K, Dansako H, Kato N, (2005) Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha. Biochem Biophys Res Commun 330: 871-879.
-
(2005)
Biochem Biophys Res Commun
, vol.330
, pp. 871-879
-
-
Naka, K.1
Ikeda, M.2
Abe, K.3
Dansako, H.4
Kato, N.5
-
17
-
-
33745903898
-
Different anti-HCV profiles of statins and their potential for combination therapy with interferon
-
Ikeda M, Abe K, Yamada M, Dansako H, Naka K, et al. (2006) Different anti-HCV profiles of statins and their potential for combination therapy with interferon. Hepatology 44: 117-125.
-
(2006)
Hepatology
, vol.44
, pp. 117-125
-
-
Ikeda, M.1
Abe, K.2
Yamada, M.3
Dansako, H.4
Naka, K.5
-
18
-
-
77950601184
-
Hydroxyurea as an inhibitor of hepatitis C virus RNA replication
-
Nozaki A, Morimoto M, Kondo M, Oshima T, Numata K, et al. (2010) Hydroxyurea as an inhibitor of hepatitis C virus RNA replication. Arch Virol 155: 601-605.
-
(2010)
Arch Virol
, vol.155
, pp. 601-605
-
-
Nozaki, A.1
Morimoto, M.2
Kondo, M.3
Oshima, T.4
Numata, K.5
-
19
-
-
79958071893
-
Anti-ulcer agent teprenone inhibits hepatitis C virus replication: potential treatment for hepatitis C
-
Ikeda M, Kawai Y, Mori K, Yano M, Abe K, et al. (2011) Anti-ulcer agent teprenone inhibits hepatitis C virus replication: potential treatment for hepatitis C. Liver Int. 31: 871-880.
-
(2011)
Liver Int
, vol.31
, pp. 871-880
-
-
Ikeda, M.1
Kawai, Y.2
Mori, K.3
Yano, M.4
Abe, K.5
-
20
-
-
70350233422
-
Efficient replication systems for hepatitis C virus using a new human hepatoma cell line
-
Kato N, Mori K, Abe K, Dansako H, Kuroki M, et al. (2009) Efficient replication systems for hepatitis C virus using a new human hepatoma cell line. Virus Res 146: 41-50.
-
(2009)
Virus Res
, vol.146
, pp. 41-50
-
-
Kato, N.1
Mori, K.2
Abe, K.3
Dansako, H.4
Kuroki, M.5
-
21
-
-
78649872069
-
Gene expression profile of Li23, a new human hepatoma cell line that enables robust hepatitis C virus replication: Comparison with HuH-7 and other hepatic cell lines
-
Mori K, Ikeda M, Ariumi Y, Kato N, (2010) Gene expression profile of Li23, a new human hepatoma cell line that enables robust hepatitis C virus replication: Comparison with HuH-7 and other hepatic cell lines. Hepatol Res 40: 1248-1253.
-
(2010)
Hepatol Res
, vol.40
, pp. 1248-1253
-
-
Mori, K.1
Ikeda, M.2
Ariumi, Y.3
Kato, N.4
-
22
-
-
79953025461
-
Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system
-
Mori K, Ikeda M, Ariumi Y, Dansako H, Wakita T, et al. (2011) Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system. Virus Res 157: 61-70.
-
(2011)
Virus Res
, vol.157
, pp. 61-70
-
-
Mori, K.1
Ikeda, M.2
Ariumi, Y.3
Dansako, H.4
Wakita, T.5
-
23
-
-
84884981804
-
Adenosine kinase is a key determinant for the anti-HCV activity of ribavirin
-
in press
-
Mori K, Hiraoka O, Ikeda M, Ariumi Y, Hiramoto A, et al. (2013) Adenosine kinase is a key determinant for the anti-HCV activity of ribavirin. Hepatology in press.
-
(2013)
Hepatology
-
-
Mori, K.1
Hiraoka, O.2
Ikeda, M.3
Ariumi, Y.4
Hiramoto, A.5
-
24
-
-
79959283124
-
Plural assay systems derived from different cell lines and hepatitis C virus strains are required for the objective evaluation of anti-hepatitis C virus reagents
-
Ueda Y, Mori K, Ariumi Y, Ikeda M, Kato N, (2011) Plural assay systems derived from different cell lines and hepatitis C virus strains are required for the objective evaluation of anti-hepatitis C virus reagents. Biochem Biophys Res Commun 409: 663-668.
-
(2011)
Biochem Biophys Res Commun
, vol.409
, pp. 663-668
-
-
Ueda, Y.1
Mori, K.2
Ariumi, Y.3
Ikeda, M.4
Kato, N.5
-
25
-
-
33746813574
-
Hemin potentiates the anti-hepatitis C virus activity of the antimalarial drug artemisinin
-
Paeshuyse J, Coelmont L, Vliegen I, Van Hemel J, Vandenkerckhove J, et al. (2006) Hemin potentiates the anti-hepatitis C virus activity of the antimalarial drug artemisinin. Biochem Biophys Res Commun 348: 139-144.
-
(2006)
Biochem Biophys Res Commun
, vol.348
, pp. 139-144
-
-
Paeshuyse, J.1
Coelmont, L.2
Vliegen, I.3
Van Hemel, J.4
Vandenkerckhove, J.5
-
26
-
-
0035811454
-
Synthesis and antimalarial activity of novel medium-sized 1,2,4,5-tetraoxacycloalkanes
-
Kim HS, Nagai Y, Ono K, Begum K, Wataya Y, et al. (2001) Synthesis and antimalarial activity of novel medium-sized 1,2,4,5-tetraoxacycloalkanes. J Med Chem 44: 2357-2361.
-
(2001)
J Med Chem
, vol.44
, pp. 2357-2361
-
-
Kim, H.S.1
Nagai, Y.2
Ono, K.3
Begum, K.4
Wataya, Y.5
-
27
-
-
79959523974
-
Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol
-
Sato A, Hiramoto A, Morita M, Matsumoto M, Komich Y, et al. (2011) Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol. Parasitol Int 60: 270-273.
-
(2011)
Parasitol Int
, vol.60
, pp. 270-273
-
-
Sato, A.1
Hiramoto, A.2
Morita, M.3
Matsumoto, M.4
Komich, Y.5
-
28
-
-
82155172896
-
Antimalarial activity of 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) and its carboxylic acid derivatives
-
Sato A, Kawai S, Hiramoto A, Morita M, Tanigawa N, et al. (2011) Antimalarial activity of 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) and its carboxylic acid derivatives. Parasitol Int 60: 488-492.
-
(2011)
Parasitol Int
, vol.60
, pp. 488-492
-
-
Sato, A.1
Kawai, S.2
Hiramoto, A.3
Morita, M.4
Tanigawa, N.5
-
29
-
-
84862667513
-
Development of hepatitis C virus production reporter-assay systems using two different hepatoma cell lines
-
Takeda M, Ikeda M, Ariumi Y, Wakita T, Kato N, (2012) Development of hepatitis C virus production reporter-assay systems using two different hepatoma cell lines. J Gen Virol 93: 1422-1431.
-
(2012)
J Gen Virol
, vol.93
, pp. 1422-1431
-
-
Takeda, M.1
Ikeda, M.2
Ariumi, Y.3
Wakita, T.4
Kato, N.5
-
30
-
-
84863718301
-
Development of a drug assay system with hepatitis C virus genome derived from a patient with acute hepatitis C
-
Mori K, Ueda Y, Ariumi Y, Dansako H, Ikeda M, et al. (2012) Development of a drug assay system with hepatitis C virus genome derived from a patient with acute hepatitis C. Virus Genes. 44: 374-381.
-
(2012)
Virus Genes
, vol.44
, pp. 374-381
-
-
Mori, K.1
Ueda, Y.2
Ariumi, Y.3
Dansako, H.4
Ikeda, M.5
-
31
-
-
62049083765
-
Replicons from genotype 1b HCV-positive sera exhibit diverse sensitivities to anti-HCV reagents
-
Nishimura G, Ikeda M, Mori K, Nakazawa T, Ariumi Y, et al. (2009) Replicons from genotype 1b HCV-positive sera exhibit diverse sensitivities to anti-HCV reagents. Antiviral Res 82: 42-50.
-
(2009)
Antiviral Res
, vol.82
, pp. 42-50
-
-
Nishimura, G.1
Ikeda, M.2
Mori, K.3
Nakazawa, T.4
Ariumi, Y.5
-
32
-
-
0041630597
-
Establishment of a hepatitis C virus subgenomic replicon derived from human hepatocytes infected in vitro
-
Kato N, Sugiyama K, Namba K, Dansako H, Nakamura T, et al. (2003) Establishment of a hepatitis C virus subgenomic replicon derived from human hepatocytes infected in vitro. Biochem Biophys Res Commun 306: 756-766.
-
(2003)
Biochem Biophys Res Commun
, vol.306
, pp. 756-766
-
-
Kato, N.1
Sugiyama, K.2
Namba, K.3
Dansako, H.4
Nakamura, T.5
-
33
-
-
33847624986
-
Proteome analysis of new antimalarial endoperoxide against Plasmodium falciparum
-
Aly NS, Hiramoto A, Sanai H, Hiraoka O, Hiramoto K, et al. (2007) Proteome analysis of new antimalarial endoperoxide against Plasmodium falciparum. Parasitol Res 100: 1119-1124.
-
(2007)
Parasitol Res
, vol.100
, pp. 1119-1124
-
-
Aly, N.S.1
Hiramoto, A.2
Sanai, H.3
Hiraoka, O.4
Hiramoto, K.5
-
34
-
-
0038416107
-
Antimalarial activity of novel 1,2,5,6-tetraoxacycloalkanes and 1,2,5-trioxacycloalkanes
-
Kim HS, Begum K, Ogura N, Wataya Y, Nonami Y, et al. (2003) Antimalarial activity of novel 1,2,5,6-tetraoxacycloalkanes and 1,2,5-trioxacycloalkanes. J Med Chem 46: 1957-1961.
-
(2003)
J Med Chem
, vol.46
, pp. 1957-1961
-
-
Kim, H.S.1
Begum, K.2
Ogura, N.3
Wataya, Y.4
Nonami, Y.5
-
35
-
-
46349106552
-
New efficient replication system with hepatitis C virus genome derived from a patient with acute hepatitis C
-
Mori K, Abe K, Dansako H, Ariumi Y, Ikeda M, et al. (2008) New efficient replication system with hepatitis C virus genome derived from a patient with acute hepatitis C. Biochem Biophys Res Commun. 371: 104-109.
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 104-109
-
-
Mori, K.1
Abe, K.2
Dansako, H.3
Ariumi, Y.4
Ikeda, M.5
-
36
-
-
33947136220
-
Cell culture-adaptive NS3 mutations required for the robust replication of genome-length hepatitis C virus RNA
-
Abe K, Ikeda M, Dansako H, Naka K, Kato N, (2007) Cell culture-adaptive NS3 mutations required for the robust replication of genome-length hepatitis C virus RNA. Virus Res 125: 88-97.
-
(2007)
Virus Res
, vol.125
, pp. 88-97
-
-
Abe, K.1
Ikeda, M.2
Dansako, H.3
Naka, K.4
Kato, N.5
-
37
-
-
34250202525
-
Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture
-
Yano M, Ikeda M, Abe K, Dansako H, Ohkoshi S, et al. (2007) Comprehensive analysis of the effects of ordinary nutrients on hepatitis C virus RNA replication in cell culture. Antimicrob Agents Chemother 51: 2016-2027.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 2016-2027
-
-
Yano, M.1
Ikeda, M.2
Abe, K.3
Dansako, H.4
Ohkoshi, S.5
-
38
-
-
70349229385
-
Oxidative stress induces anti-hepatitis C virus status via the activation of extracellular signal-regulated kinase
-
Yano M, Ikeda M, Abe K, Kawai Y, Kuroki M, et al. (2009) Oxidative stress induces anti-hepatitis C virus status via the activation of extracellular signal-regulated kinase. Hepatology 50: 678-688.
-
(2009)
Hepatology
, vol.50
, pp. 678-688
-
-
Yano, M.1
Ikeda, M.2
Abe, K.3
Kawai, Y.4
Kuroki, M.5
-
39
-
-
78149359284
-
Shrinking the malaria map: progress and prospects
-
Feachem RG, Phillips AA, Hwang J, Cotter C, Wielgosz B, et al. (2010) Shrinking the malaria map: progress and prospects. Lancet 376: 1566-1578.
-
(2010)
Lancet
, vol.376
, pp. 1566-1578
-
-
Feachem, R.G.1
Phillips, A.A.2
Hwang, J.3
Cotter, C.4
Wielgosz, B.5
-
41
-
-
84870884133
-
Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251
-
Morita M, Sanai H, Hiramoto A, Sato A, Hiraoka O, et al. (2012) Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251. J Proteome Res 11: 5704-5711.
-
(2012)
J Proteome Res
, vol.11
, pp. 5704-5711
-
-
Morita, M.1
Sanai, H.2
Hiramoto, A.3
Sato, A.4
Hiraoka, O.5
-
42
-
-
84878173326
-
Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C
-
in press
-
Rotman Y, Noureddin M, Feld JJ, Guedj J, Witthaus M, et al. (2013) Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C. Gut in press.
-
(2013)
Gut
-
-
Rotman, Y.1
Noureddin, M.2
Feld, J.J.3
Guedj, J.4
Witthaus, M.5
|