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Volumn 116, Issue , 2013, Pages 876-881
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Determination of the trypanocidal drug melarsoprol and its conversion products in biological fluids with HPLC-ICPMS/ESMS
a
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Author keywords
Arsenic; HPLC ICPMS ESMS; Melarsoprol Sleeping sickness
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Indexed keywords
ARSENIC;
BIOASSAY;
BLOOD;
DISEASES;
DRUG PRODUCTS;
INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY;
METABOLITES;
PROTEINS;
SIGNAL TO NOISE RATIO;
ACCURATE MASS MEASUREMENTS;
ACTIVE METABOLITES;
BLOOD-BRAIN BARRIER;
DIRECT DETERMINATION;
HPLC-ICPMS/ESMS;
PROTEIN PRECIPITATION;
QUANTITATIVE MEASUREMENT;
SLEEPING SICKNESS;
ARSENIC COMPOUNDS;
ANTITRYPANOSOMAL AGENT;
ARSENIC;
MELARSEN;
MELARSOPROL;
ORGANOARSENIC DERIVATIVE;
PLASMA PROTEIN;
AFRICAN TRYPANOSOMIASIS;
ARTICLE;
ATOMIC ABSORPTION SPECTROMETRY;
BIOTRANSFORMATION;
BLOOD;
BLOOD CELL;
CELL CULTURE;
CHEMISTRY;
CYTOLOGY;
DRUG EFFECT;
DRUG STABILITY;
ELECTROSPRAY MASS SPECTROMETRY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HPLC-ICPMS/ESMS;
HUMAN;
LIMIT OF DETECTION;
METABOLISM;
PROTEIN BINDING;
SERUM;
ARSENIC;
HPLC-ICPMS/ESMS;
MELARSOPROL;
SLEEPING SICKNESS;
ARSENIC;
ARSENICALS;
BIOTRANSFORMATION;
BLOOD CELLS;
BLOOD PROTEINS;
CELLS, CULTURED;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG STABILITY;
HUMANS;
LIMIT OF DETECTION;
MELARSOPROL;
PROTEIN BINDING;
SERUM;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
SPECTROPHOTOMETRY, ATOMIC;
TRYPANOCIDAL AGENTS;
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EID: 84883403294
PISSN: 00399140
EISSN: None
Source Type: Journal
DOI: 10.1016/j.talanta.2013.07.066 Document Type: Article |
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Times cited : (7)
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References (18)
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