Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis

FEBS Journal

Volumn 280, Issue 18, 2013, Pages 4640-4651

  Achcar, Fiona ^a   Barrett, Michael P ^a   Breitling, Rainer ^a,b,c  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

computational modelling; glycolysis; parameter sampling; systems biology; topological uncertainty

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; GLUCOSE; GLYCOLYTIC ENZYME;

AEROBIC METABOLISM; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE INTAKE; GLYCOLYSIS; GLYCOSOME; MATHEMATICAL MODEL; MEMBRANE STRUCTURE; METABOLIC REGULATION; METABOLITE; MOLECULAR MODEL; NONHUMAN; NUCLEAR PORE; PARASITE VIABILITY; PRIORITY JOURNAL; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

COMPUTATIONAL MODELLING; GLYCOLYSIS; PARAMETER SAMPLING; SYSTEMS BIOLOGY; TOPOLOGICAL UNCERTAINTY;

BIOLOGICAL TRANSPORT; CELL COMPARTMENTATION; CYTOSOL; GLUCOSE; GLYCOLYSIS; INTRACELLULAR MEMBRANES; KINETICS; MICROBODIES; MODELS, STATISTICAL; PERMEABILITY; TRYPANOSOMA BRUCEI BRUCEI; UNCERTAINTY;

EID: 84883399470     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12436     Document Type: Article

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