메뉴 건너뛰기




Volumn 288, Issue 35, 2013, Pages 25129-25142

Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN; LIVING CELL; MACROMOLECULAR COMPOSITION; PROTEIN COMPLEXES; STRIATUM;

EID: 84883379662     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.462283     Document Type: Article
Times cited : (43)

References (41)
  • 1
    • 0038234801 scopus 로고    scopus 로고
    • G-proteins as transducers in transmembrane signalling
    • Offermanns, S. (2003) G-proteins as transducers in transmembrane signalling. Prog. Biophys. Mol. Biol. 83, 101-130
    • (2003) Prog. Biophys. Mol. Biol , vol.83 , pp. 101-130
    • Offermanns, S.1
  • 2
    • 0036733358 scopus 로고    scopus 로고
    • Cellular regulation of RGS proteins. Modulators and integrators of G protein signaling
    • Hollinger, S., and Hepler, J. R. (2002) Cellular regulation of RGS proteins. Modulators and integrators of G protein signaling. Pharmacol. Rev. 54, 527-559
    • (2002) Pharmacol. Rev , vol.54 , pp. 527-559
    • Hollinger, S.1    Hepler, J.R.2
  • 3
    • 0033783132 scopus 로고    scopus 로고
    • GTPase-activating proteins for heterotrimeric G proteins. Regulators of G protein signaling (RGS) and RGSlike proteins
    • Ross, E. M., and Wilkie, T. M. (2000) GTPase-activating proteins for heterotrimeric G proteins. Regulators of G protein signaling (RGS) and RGSlike proteins. Annu. Rev. Biochem. 69, 795-827
    • (2000) Annu. Rev. Biochem , vol.69 , pp. 795-827
    • Ross, E.M.1    Wilkie, T.M.2
  • 4
    • 17844400914 scopus 로고    scopus 로고
    • The repertoire of G-proteincoupled receptors in fully sequenced genomes
    • Fredriksson, R., and Schiöth, H. B. (2005) The repertoire of G-proteincoupled receptors in fully sequenced genomes. Mol. Pharmacol. 67, 1414-1425
    • (2005) Mol. Pharmacol , vol.67 , pp. 1414-1425
    • Fredriksson, R.1    Schiöth, H.B.2
  • 5
    • 25444482429 scopus 로고    scopus 로고
    • Mammalian G proteins and their cell type specific functions
    • Wettschureck, N., and Offermanns, S. (2005) Mammalian G proteins and their cell type specific functions. Physiol. Rev. 85, 1159-1204
    • (2005) Physiol. Rev , vol.85 , pp. 1159-1204
    • Wettschureck, N.1    Offermanns, S.2
  • 7
    • 84862990400 scopus 로고    scopus 로고
    • Control of striatal signaling by g protein regulators
    • Xie, K., and Martemyanov, K. A. (2011) Control of striatal signaling by g protein regulators. Front. Neuroanat. 5, 49
    • (2011) Front. Neuroanat , vol.5 , pp. 49
    • Xie, K.1    Martemyanov, K.A.2
  • 8
    • 67651017881 scopus 로고    scopus 로고
    • Physiology and pharmacology of striatal neurons
    • Kreitzer, A. C. (2009) Physiology and pharmacology of striatal neurons. Annu. Rev. Neurosci. 32, 127-147
    • (2009) Annu. Rev. Neurosci , vol.32 , pp. 127-147
    • Kreitzer, A.C.1
  • 9
    • 61349171291 scopus 로고    scopus 로고
    • RGS9-2. Probing an intracellular modulator of behavior as a drug target
    • Traynor, J. R., Terzi, D., Caldarone, B. J., and Zachariou, V. (2009) RGS9-2. Probing an intracellular modulator of behavior as a drug target. Trends Pharmacol. Sci. 30, 105-111
    • (2009) Trends Pharmacol. Sci , vol.30 , pp. 105-111
    • Traynor, J.R.1    Terzi, D.2    Caldarone, B.J.3    Zachariou, V.4
  • 10
    • 68549106027 scopus 로고    scopus 로고
    • The R7 RGS protein family. Multi-subunit regulators of neuronal G protein signaling
    • Anderson, G. R., Posokhova, E., and Martemyanov, K. A. (2009) The R7 RGS protein family. Multi-subunit regulators of neuronal G protein signaling. Cell Biochem. Biophys. 54, 33-46
    • (2009) Cell Biochem. Biophys , vol.54 , pp. 33-46
    • Anderson, G.R.1    Posokhova, E.2    Martemyanov, K.A.3
  • 13
    • 20044362374 scopus 로고    scopus 로고
    • D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways
    • Kovoor, A., Seyffarth, P., Ebert, J., Barghshoon, S., Chen, C. K., Schwarz, S., Axelrod, J. D., Cheyette, B. N., Simon, M. I., Lester, H. A., and Schwarz, J. (2005) D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. J. Neurosci. 25, 2157-2165
    • (2005) J. Neurosci , vol.25 , pp. 2157-2165
    • Kovoor, A.1    Seyffarth, P.2    Ebert, J.3    Barghshoon, S.4    Chen, C.K.5    Schwarz, S.6    Axelrod, J.D.7    Cheyette, B.N.8    Simon, M.I.9    Lester, H.A.10    Schwarz, J.11
  • 20
    • 14044273637 scopus 로고    scopus 로고
    • R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family
    • Martemyanov, K. A., Yoo, P. J., Skiba, N. P., and Arshavsky, V. Y. (2005) R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family. J. Biol. Chem. 280, 5133-5136
    • (2005) J. Biol. Chem , vol.280 , pp. 5133-5136
    • Martemyanov, K.A.1    Yoo, P.J.2    Skiba, N.P.3    Arshavsky, V.Y.4
  • 21
    • 38449085211 scopus 로고    scopus 로고
    • Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases
    • Anderson, G. R., Lujan, R., Semenov, A., Pravetoni, M., Posokhova, E. N., Song, J. H., Uversky, V., Chen, C. K., Wickman, K., and Martemyanov, K. A. (2007) Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases. J. Neurosci. 27, 14117-14127
    • (2007) J. Neurosci , vol.27 , pp. 14117-14127
    • Anderson, G.R.1    Lujan, R.2    Semenov, A.3    Pravetoni, M.4    Posokhova, E.N.5    Song, J.H.6    Uversky, V.7    Chen, C.K.8    Wickman, K.9    Martemyanov, K.A.10
  • 23
    • 0038485601 scopus 로고    scopus 로고
    • Gγ subunit-selective G protein β 5 mutant defines regulators of G protein signaling protein binding requirement for nuclear localization
    • Rojkova, A. M., Woodard, G. E., Huang, T. C., Combs, C. A., Zhang, J. H., and Simonds, W. F. (2003) Gγ subunit-selective G protein β 5 mutant defines regulators of G protein signaling protein binding requirement for nuclear localization. J. Biol. Chem. 278, 12507-12512
    • (2003) J. Biol. Chem , vol.278 , pp. 12507-12512
    • Rojkova, A.M.1    Woodard, G.E.2    Huang, T.C.3    Combs, C.A.4    Zhang, J.H.5    Simonds, W.F.6
  • 24
    • 77951199474 scopus 로고    scopus 로고
    • Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gβ5 complex and accelerates inactivation of the mGluR6-G(o) signaling
    • Masuho, I., Celver, J., Kovoor, A., and Martemyanov, K. A. (2010) Membrane anchor R9AP potentiates GTPase-accelerating protein activity of RGS11 x Gβ5 complex and accelerates inactivation of the mGluR6-G(o) signaling. J. Biol. Chem. 285, 4781-4787
    • (2010) J. Biol. Chem , vol.285 , pp. 4781-4787
    • Masuho, I.1    Celver, J.2    Kovoor, A.3    Martemyanov, K.A.4
  • 25
    • 62749156042 scopus 로고    scopus 로고
    • The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers
    • Hollins, B., Kuravi, S., Digby, G. J., and Lambert, N. A. (2009) The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers. Cell. Signal. 21, 1015-1021
    • (2009) Cell. Signal , vol.21 , pp. 1015-1021
    • Hollins, B.1    Kuravi, S.2    Digby, G.J.3    Lambert, N.A.4
  • 26
    • 0038193543 scopus 로고    scopus 로고
    • RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity
    • Hooks, S. B., Waldo, G. L., Corbitt, J., Bodor, E. T., Krumins, A. M., and Harden, T. K. (2003) RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity. J. Biol. Chem. 278, 10087-10093
    • (2003) J. Biol. Chem , vol.278 , pp. 10087-10093
    • Hooks, S.B.1    Waldo, G.L.2    Corbitt, J.3    Bodor, E.T.4    Krumins, A.M.5    Harden, T.K.6
  • 27
    • 75649091541 scopus 로고    scopus 로고
    • RSBP-1 is a membrane-targeting subunit required by the Gα(q)-specific but not the Gα(o)-specific R7 regulator of G protein signaling in Caenorhabditis elegans
    • Porter, M. Y., and Koelle, M. R. (2010) RSBP-1 is a membrane-targeting subunit required by the Gα(q)-specific but not the Gα(o)-specific R7 regulator of G protein signaling in Caenorhabditis elegans. Mol. Biol. Cell 21, 232-243
    • (2010) Mol. Biol. Cell , vol.21 , pp. 232-243
    • Porter, M.Y.1    Koelle, M.R.2
  • 28
    • 0025192474 scopus 로고
    • Gz, a guanine nucleotide-binding protein with unique biochemical properties
    • Casey, P. J., Fong, H. K., Simon, M. I., and Gilman, A. G. (1990) Gz, a guanine nucleotide-binding protein with unique biochemical properties. J. Biol. Chem. 265, 2383-2390
    • (1990) J. Biol. Chem , vol.265 , pp. 2383-2390
    • Casey, P.J.1    Fong, H.K.2    Simon, M.I.3    Gilman, A.G.4
  • 29
    • 30944451158 scopus 로고    scopus 로고
    • RGS proteins have a signalling complex. Interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins
    • Abramow-Newerly, M., Roy, A. A., Nunn, C., and Chidiac, P. (2006) RGS proteins have a signalling complex. Interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins. Cell. Signal. 18, 579-591
    • (2006) Cell. Signal , vol.18 , pp. 579-591
    • Abramow-Newerly, M.1    Roy, A.A.2    Nunn, C.3    Chidiac, P.4
  • 30
    • 58149129117 scopus 로고    scopus 로고
    • R9AP and R7BP. Traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling
    • Jayaraman, M., Zhou, H., Jia, L., Cain, M. D., and Blumer, K. J. (2009) R9AP and R7BP. Traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling. Trends Pharmacol. Sci. 30, 17-24
    • (2009) Trends Pharmacol. Sci , vol.30 , pp. 17-24
    • Jayaraman, M.1    Zhou, H.2    Jia, L.3    Cain, M.D.4    Blumer, K.J.5
  • 32
    • 77954346676 scopus 로고    scopus 로고
    • RGS9-2 mediates specific inhibition of agonist-induced internalization of D2-dopamine receptors
    • Celver, J., Sharma, M., and Kovoor, A. (2010) RGS9-2 mediates specific inhibition of agonist-induced internalization of D2-dopamine receptors. J. Neurochem. 114, 739-749
    • (2010) J. Neurochem , vol.114 , pp. 739-749
    • Celver, J.1    Sharma, M.2    Kovoor, A.3
  • 35
    • 19244367478 scopus 로고    scopus 로고
    • The R7 subfamily of RGS proteins assists tachyphylaxis and acute tolerance at μ-opioid receptors
    • Garzón, J., López-Fando, A., and Sánchez- Blázquez, P. (2003) The R7 subfamily of RGS proteins assists tachyphylaxis and acute tolerance at μ-opioid receptors. Neuropsychopharmacology 28, 1983-1990
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1983-1990
    • Garzón, J.1    López-Fando, A.2    Sánchez-Blázquez, P.3
  • 36
    • 64349091535 scopus 로고    scopus 로고
    • The Gβ5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7
    • Sandiford, S. L., and Slepak, V. Z. (2009) The Gβ5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7. Biochemistry 48, 2282-2289
    • (2009) Biochemistry , vol.48 , pp. 2282-2289
    • Sandiford, S.L.1    Slepak, V.Z.2
  • 37
    • 84863995921 scopus 로고    scopus 로고
    • GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes
    • Orlandi, C., Posokhova, E., Masuho, I., Ray, T. A., Hasan, N., Gregg, R. G., and Martemyanov, K. A. (2012) GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes. J. Cell Biol. 197, 711-719
    • (2012) J. Cell Biol , vol.197 , pp. 711-719
    • Orlandi, C.1    Posokhova, E.2    Masuho, I.3    Ray, T.A.4    Hasan, N.5    Gregg, R.G.6    Martemyanov, K.A.7
  • 38
    • 0038198731 scopus 로고    scopus 로고
    • Specificity of G protein-RGS protein recognition is regulated by affinity adapters
    • Martemyanov, K. A., Hopp, J. A., and Arshavsky, V. Y. (2003) Specificity of G protein-RGS protein recognition is regulated by affinity adapters. Neuron 38, 857-862
    • (2003) Neuron , vol.38 , pp. 857-862
    • Martemyanov, K.A.1    Hopp, J.A.2    Arshavsky, V.Y.3
  • 39
    • 67650563911 scopus 로고    scopus 로고
    • Differential modulation of μ- And δ-opioid receptor agonists by endogenous RGS4 protein in SH-SY5Y cells
    • Wang, Q., Liu-Chen, L. Y., and Traynor, J. R. (2009) Differential modulation of μ- and δ-opioid receptor agonists by endogenous RGS4 protein in SH-SY5Y cells. J. Biol. Chem. 284, 18357-18367
    • (2009) J. Biol. Chem , vol.284 , pp. 18357-18367
    • Wang, Q.1    Liu-Chen, L.Y.2    Traynor, J.R.3
  • 40
    • 66349138500 scopus 로고    scopus 로고
    • Changes in striatal signaling induce remodeling of RGS complexes containing Gβ5 and R7BP subunits
    • Anderson, G. R., Lujan, R., and Martemyanov, K. A. (2009) Changes in striatal signaling induce remodeling of RGS complexes containing Gβ5 and R7BP subunits. Mol. Cell Biol. 29, 3033-3044
    • (2009) Mol. Cell Biol , vol.29 , pp. 3033-3044
    • Anderson, G.R.1    Lujan, R.2    Martemyanov, K.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.