Neonatal MK-801 treatment differentially alters the effect of adolescent or adult MK-801 challenge on locomotion and PPI in male and female rats

Journal of Psychopharmacology

Volumn 27, Issue 9, 2013, Pages 845-853

  Zhao, Ying Ying ^a   Li, Ji Tao ^a   Wang, Xiao Dong ^a   Li, You Hong ^a   Huang, Run Hu ^a   Su, Yun Ai ^a   Si, Tian Mei ^a  

^a PEKING UNIVERSITY SIXTH HOSPITAL   (China)

Author keywords

locomotor activity; MK 801; NMDA receptor; PPI; schizophrenia

Indexed keywords

DIZOCILPINE;

ADOLESCENCE; ADOLESCENT; ADULT ANIMAL; ADULTHOOD; AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; FEMALE; HYPERACTIVITY; LOCOMOTION; LONG TERM EXPOSURE; MALE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PREPULSE INHIBITION; PRIORITY JOURNAL; RAT; SCHIZOPHRENIA; SENSITIZATION; SEX DIFFERENCE; STARTLE REFLEX;

LOCOMOTOR ACTIVITY; MK-801; NMDA RECEPTOR; PPI; SCHIZOPHRENIA;

ANIMALS; DIZOCILPINE MALEATE; FEMALE; LOCOMOTION; MALE; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SCHIZOPHRENIA;

EID: 84883365078     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881113497613     Document Type: Article

References (45)

1. Al-Amin HA, Shannon Weickert C, Weinberger DR, et al. Delayed onset of enhanced MK-801-induced motor hyperactivity after neonatal lesions of the rat ventral hippocampus. Bio Psychiat. 2001 ; 49: 528-539
2. Andine P, Widermark N, Axelsson R, et al. Characterization of MK-801-induced behavior as a putative rat model of psychosis. J Pharmacol Exp Ther. 1999 ; 290: 1393-1408
3. Bakshi VP, Geyer MA. Multiple limbic regions mediate the disruption of prepulse inhibition produced in rats by the noncompetitive nmda antagonist dizocilpine. J Neurosci. 1998 ; 18: 8394-8401
4. Bayer TA, Falkai P, Maier W. Genetic and non-genetic vulnerability factors in schizophrenia: The basis of the "two hit hypothesis". J Psychiatr Res. 1999 ; 33: 543-548
5. Becker A, Peters B, Schroeder H, et al. Ketamine-induced changes in rat behaviour: A possible animal model of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2003 ; 27: 687-700
6. Beninger R, Jhamandas A, Aujla H, et al. Neonatal Exposure to the glutamate receptor antagonist MK-801: Effects on locomotor activity and pre-pulse inhibition before and after sexual maturity in rats. Neurotox Res. 2002 ; 4: 477-488
7. Boctor SY, Ferguson SA. Altered adult locomotor activity in rats from phencyclidine treatment on postnatal days 7, 9 and 11, but not repeated ketamine treatment on postnatal day 7. NeuroToxicology. 2010 ; 31: 42-54
8. Bubenikova-Valesova V, Horacek J, Vrajova M, et al. Models of schizophrenia in humans and animals based on inhibition of NMDA receptors. Neurosci Biobehav Rev. 2008 ; 32: 1014-1023
9. Cannon TD, Rosso IM, Hollister JM, et al. A prospective cohort study of genetic and perinatal influences in the etiology of schizophrenia. Schizophr Bull. 2000 ; 26: 351-366
10. Chavez C, Gogos A, Jones ME, et al. Psychotropic Drug-induced locomotor hyperactivity and prepulse inhibition regulation in male and female aromatase knockout (Arko) mice: Role of dopamine D1 and D2 receptors and dopamine transporters. Psychopharmacology (Berl). 2009 ; 206: 267-279
11. Choy KH, Van Den Buuse M. Attenuated disruption of prepulse inhibition by dopaminergic stimulation after maternal deprivation and adolescent corticosterone treatment in rats. Eur Neuropsychopharmacol. 2008 ; 18: 1-13
12. Coyle JT, Tsai G, Goff D. Converging evidence of nmda receptor hypofunction in the pathophysiology of schizophrenia. Ann N Y Acad Sci. 2003 ; 1003: 318-327
13. Culm KE, Hammer RP. Recovery of sensorimotor gating without G protein adaptation after repeated D2-like dopamine receptor agonist treatment in rats. J Pharmacol Exp Ther. 2004 ; 308: 487-494
14. Druhan JP, Geyer MA, Valentino RJ. Lack of Sensitization to the Effects of D-Amphetamine and Apomorphine on Sensorimotor Gating in Rats. Psychopharmacology. 1998 ; 135: 296-304
15. Du Bois TM, Deng C, Han M, et al. Excitatory and Inhibitory Neurotransmission Is Chronically Altered Following Perinatal Nmda Receptor Blockade. Eur Neuropsychopharm. 2009 ; 19: 256-265
16. Gogos A, Kwek P, Van Den Buuse M. The role of estrogen and testosterone in female rats in behavioral models of relevance to schizophrenia. Psychopharmacology. 2012 ; 219: 213-224
17. Haberny KA, Paule MG, Scallet AC, et al. Ontogeny of the N-methyl-D-aspartate (NMDA) receptor system and susceptibility to neurotoxicity. Toxicol Sci. 2002 ; 68: 9-17
18. Hultman CM, Sparen P, Takei N, et al. Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: Case-control study. BMJ. 1999 ; 318: 421-426
19. Javitt DC, Zukin SR. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry. 1991 ; 148: 1301-1308
20. Kirch DG. Infection and autoimmunity as etiologic factors in schizophrenia: A review and reappraisal. Schizophr Bull. 1993 ; 19: 355-370
21. Koch M. Sensorimotor gating changes across the estrous cycle in female rats. Physiol Behav. 1998 ; 64: 625-628
22. Lahti AC, Koffel B, Laporte D, et al. Subanesthetic doses of ketamine stimulate psychosis in schizophrenia. Neuropsychopharmacology. 1995 ; 13: 9-19
23. Lewis DA, Hashimoto T, Volk DW. Cortical inhibitory neurons and schizophrenia. Nat Rev Neurosci. 2005 ; 6: 312-324
24. Li M, Mead A, Bevins RA. Individual differences in responses to nicotine: Tracking changes from adolescence to adulthood. Acta Pharmacol Sin. 2009 ; 30: 868-878
25. Lieberman JA, Kane JM, Alvir J. Provocative Tests with Psychostimulant Drugs in Schizophrenia. Psychopharmacology (Berl). 1987 ; 91: 415-433
26. Lieberman JA, Sheitman BB, Kinon BJ. Neurochemical sensitization in the pathophysiology of schizophrenia: Deficits and dysfunction in neuronal regulation and plasticity. Neuropsychopharmacology. 1997 ; 17: 205-229
27. Lim AL, Taylor DA, Malone DT. Consequences of early life MK-801 administration: Long-term behavioural effects and relevance to schizophrenia research. Behav Brain Res. 2012 ; 227: 276-286
28. Lim AL, Taylor DA, Malone DT. A two-hit model: Behavioural investigation of the effect of combined neonatal MK-801 administration and isolation rearing in the rat. J Psychopharmacol. 2012 ; 26: 1252-1264
29. Lisman JE, Coyle JT, Green RW, et al. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 2008 ; 31: 234-242
30. Lyall A, Swanson J, Liu C, et al. Neonatal exposure to MK 801 promotes prepulse-induced delay in startle response time in adult rats. Exp Brain Res. 2009 ; 197: 215-222
31. Murray RM, O'Callaghan E, Castle DJ, et al. A Neurodevelopmental approach to the classification of schizophrenia. Schizophr Bull. 1992 ; 18: 319-332
32. Olney J, Farber N. Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry. 1995 ; 52: 998-1007
33. Ovtscharoff W, Eusterschulte B, Zienecker R, et al. Sex differences in densities of dopaminergic fibers and gabaergic neurons in the prenatal rat striatum. J Comp Neurol. 1992 ; 323: 299-304
34. Parducz A, Hoyk Z, Kis Z, et al. Hormonal enhancement of neuronal firing is linked to structural remodelling of excitatory and inhibitory synapses. Eur J Neurosci. 2002 ; 16: 665-670
35. Rapoport JL, Addington AM, Frangou S, et al. The neurodevelopmental model of schizophrenia: Update 2005. Mol Psychiatry. 2005 ; 10: 434-449
36. Rosso IM, Cannon TD, Huttunen T, et al. Obstetric risk factors for early-onset schizophrenia in a Finnish birth cohort. Am J Psychiatry. 2000 ; 157: 801-807
37. Schiffelholz T, Hinze-Selch D, Aldenhoff JB. Perinatal MK-801 treatment affects age-related changes in locomotor activity from childhood to later adulthood in rats. Neurosci Lett. 2004 ; 360: 157-160
38. Stefani MR, Moghaddam B. Transient N-methyl-D-aspartate receptor blockade in early development causes lasting cognitive deficits relevant to schizophrenia. Biol Psychiatry. 2005 ; 57: 433-436
39. Su YA, Wang XD, Li JT, et al. Age-Specific effects of early MK-801 treatment on working memory in female rats. NeuroReport. 2011 ; 22: 402-406
40. Swerdlow NR, Hartman PL, Auerbach PP. Changes in sensorimotor inhibition across the menstrual cycle: Implications for neuropsychiatric disorders. Biol Psychiatry. 1997 ; 41: 452-460
41. Torrey EF. A viral-anatomical explanation of schizophrenia. Schizophr Bull. 1991 ; 17: 15-18
42. Tseng KY, O'Donnell P. D2 dopamine receptors recruit a gaba component for their attenuation of excitatory synaptic transmission in the adult rat prefrontal cortex. Synapse. 2007 ; 61: 843-850
43. Uehara T, Sumiyoshi T, Seo T, et al. Long-term effects of neonatal MK-801 treatment on prepulse inhibition in young adult rats. Psychopharmacology (Berl). 2009 ; 206: 623-630
44. Uehara T, Sumiyoshi T, Seo T, et al. Neonatal exposure to MK-801, an N-methyl-D-aspartate receptor antagonist, enhances methamphetamine-induced locomotion and disrupts sensorimotor gating in pre- and postpubertal rats. Brain Res. 2010 ; 1352: 223-230
45. Wang C, Mcinnis J, Ross-Sanchez M, et al. Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia. Neuroscience. 2001 ; 107: 535-550