DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Weiss, Celine S ^a   Ochs, Marco M ^a   Hagenmueller, Marco ^a   Streit, Marcus R ^a   Malekar, Pratima ^a   Riffel, Johannes H ^a   Buss, Sebastian J ^a   Weiss, Karl H ^a   Sadoshima, Junichi ^b   Katus, Hugo A ^a   Hardt, Stefan E ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GLYCOGEN SYNTHASE KINASE 3BETA; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INITIATION FACTOR 2BEPSILON; ISOPRENALINE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE DYR2; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADRENERGIC STIMULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL GROWTH; CELL SIZE; CONTROLLED STUDY; DOWN REGULATION; DRUG TARGETING; DYRK2 GENE; EIF2BEPSILON GENE; ENZYME INHIBITION; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE INTERACTION; GENE OVEREXPRESSION; GENE SILENCING; GROWTH REGULATION; GSK 3BETA GENE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TRANSGENE; TRANSGENIC MOUSE; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; WILD TYPE;

ANIMALS; CELLS, CULTURED; ECHOCARDIOGRAPHY; EUKARYOTIC INITIATION FACTOR-2B; GLYCOGEN SYNTHASE KINASE 3; HYPERTROPHY, LEFT VENTRICULAR; IMMUNOPRECIPITATION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCYTES, CARDIAC; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 84883325033     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070848     Document Type: Article

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