Variable interference with interferon signal transduction by different strains of porcine reproductive and respiratory syndrome virus

Veterinary Microbiology

Volumn 166, Issue 3-4, 2013, Pages 493-503

  Wang, Rong ^a,b   Nan, Yuchen ^b   Yu, Ying ^b   Yang, Zengqi ^a   Zhang, Yan Jin ^b  

^a NORTHWEST A F UNIVERSITY   (China)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

Interferon (IFN) signaling; JAK STAT signal pathway; N; Nsp1 ; Porcine reproductive and respiratory syndrome virus (PRRSV)

Indexed keywords

ALPHA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; INTERFERON; STAT2 PROTEIN; STRUCTURAL PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTERIVIRUS; ARTICLE; GENE; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; VIRUS STRAIN;

PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; RNA VIRUSES; SUIDAE; SUS;

INTERFERON (IFN) SIGNALING; JAK/STAT SIGNAL PATHWAY; N; NSP1Β; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV);

ANIMALS; CELL LINE; HUMANS; INTERFERONS; MACROPHAGES, ALVEOLAR; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SIGNAL TRANSDUCTION; SWINE; VIRAL PROTEINS;

EID: 84883300980     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2013.07.022     Document Type: Article

References (36)

1. Albina E., Carrat C., Charley B. Interferon-alpha response to swine arterivirus (PoAV), the porcine reproductive and respiratory syndrome virus. J. Interferon Cytokine Res. 1998, 18:485-490.
2. Beura L.K., Dinh P.X., Osorio F.A., Pattnaik A.K. Cellular poly(c) binding proteins 1 and 2 interact with porcine reproductive and respiratory syndrome virus nonstructural protein 1beta and support viral replication. J. Virol. 2011, 85:12939-12949.
3. Beura L.K., Sarkar S.N., Kwon B., Subramaniam S., Jones C., Pattnaik A.K., Osorio F.A. Porcine reproductive and respiratory syndrome virus nonstructural protein 1beta modulates host innate immune response by antagonizing IRF3 activation. J. Virol. 2010, 84:1574-1584.
4. Buddaert W., Van Reeth K., Pensaert M. In vivo and in vitro interferon (IFN) studies with the porcine reproductive and respiratory syndrome virus (PRRSV). Adv. Exp. Med. Biol. 1998, 440:461-467.
5. Chen Z., Lawson S., Sun Z., Zhou X., Guan X., Christopher-Hennings J., Nelson E.A., Fang Y. Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonist. Virology 2010, 398:87-97.
6. Conzelmann K.K., Visser N., Van Woensel P., Thiel H.J. Molecular characterization of porcine reproductive and respiratory syndrome virus, a member of the arterivirus group. Virology 1993, 193:329-339.
7. Darnell J.E., Kerr I.M., Stark G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science (New York, NY) 1994, 264:1415-1421.
8. Faaberg K.S., Balasuriya U.B., Brinton M.A., Gorbalenya A.E., Leung F.C.-C., Nauwynck H., Snijder E.J., Stadejek T., Yang H., Yoo D. Family arteriviridae. Virus Taxonomy, Ninth Report of the International Committee on Taxonomy of Viruses 2011, Elsevier Academic Press, London. A.M.Q. King (Ed.).
9. Fang Y., Treffers E.E., Li Y., Tas A., Sun Z., van der Meer Y., de Ru A.H., van Veelen P.A., Atkins J.F., Snijder E.J., Firth A.E. Efficient-2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:E2920-E2928.
10. Firth A.E., Zevenhoven-Dobbe J.C., Wills N.M., Go Y.Y., Balasuriya U.B., Atkins J.F., Snijder E.J., Posthuma C.C. Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production. J. Gen. Virol. 2011, 92:1097-1106.
11. Gonzalez-Navajas J.M., Lee J., David M., Raz E. Immunomodulatory functions of type I interferons. Nat. Rev. Immunol. 2012, 12:125-135.
12. Han J., Wang Y., Faaberg K.S. Complete genome analysis of RFLP 184 isolates of porcine reproductive and respiratory syndrome virus. Virus Res. 2006, 122:175-182.
13. Johnson C.R., Griggs T.F., Gnanandarajah J., Murtaugh M.P. Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses. J. Gen. Virol. 2011, 92:1107-1116.
14. Kannan H., Fan S., Patel D., Bossis I., Zhang Y.J. The hepatitis E virus ORF3 product interacts with microtubules and interferes with their dynamics. J. Virol. 2009.
15. Kim H.S., Kwang J., Yoon I.J., Joo H.S., Frey M.L. Enhanced replication of porcine reproductive and respiratory syndrome (PRRS) virus in a homogeneous subpopulation of MA-104 cell line. Arch. Virol. 1993, 133:477-483.
16. Kim O., Sun Y., Lai F.W., Song C., Yoo D. Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells. Virology 2010, 402:315-326.
17. Labarque G.G., Nauwynck H.J., Van Reeth K., Pensaert M.B. Effect of cellular changes and onset of humoral immunity on the replication of porcine reproductive and respiratory syndrome virus in the lungs of pigs. J. Gen. Virol. 2000, 81:1327-1334.
18. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (San Diego, CA) 2001, 25:402-408.
19. Meng X.J., Paul P.S., Halbur P.G. Molecular cloning and nucleotide sequencing of the 3'-terminal genomic RNA of the porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 1994, 75(Pt 7):1795-1801.
20. Meulenberg J.J.M., Meijer E.J.d.Moormann R.J.M., De Meijer E.J. Subgenomic RNAs of Lelystad virus contain a conserved leader-body junction sequence. J. Gen. Virol. 1993, 74:1697-1701.
21. Miller L.C., Laegreid W.W., Bono J.L., Chitko-McKown C.G., Fox J.M. Interferon type I response in porcine reproductive and respiratory syndrome virus-infected MARC-145 cells. Arch. Virol. 2004, 149:2453-2463.
22. Nan Y., Wang R., Shen M., Faaberg K.S., Samal S.K., Zhang Y.J. Induction of type I interferons by a novel porcine reproductive and respiratory syndrome virus isolate. Virology 2012, 432:261-270.
23. Neumann E.J., Kliebenstein J.B., Johnson C.D., Mabry J.W., Bush E.J., Seitzinger A.H., Green A.L., Zimmerman J.J. Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States. J. Am. Vet. Med. Assoc. 2005, 227:385-392.
24. Patel D., Nan Y., Shen M., Ritthipichai K., Zhu X., Zhang Y.J. Porcine reproductive and respiratory syndrome virus inhibits type I interferon signaling by blocking STAT1/STAT2 nuclear translocation. J. Virol. 2010, 84:11045-11055.
25. Patel D., Opriessnig T., Stein D.A., Halbur P.G., Meng X.J., Iversen P.L., Zhang Y.J. Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication. Antiviral Res. 2008, 77:95-107.
26. Patel D., Stein D.A., Zhang Y.J. Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death. Antivir. Ther. 2009, 14:899-909.
27. Rowland R.R., Kervin R., Kuckleburg C., Sperlich A., Benfield D.A. The localization of porcine reproductive and respiratory syndrome virus nucleocapsid protein to the nucleolus of infected cells and identification of a potential nucleolar localization signal sequence. Virus Res. 1999, 64:1-12.
28. Schindler C., Darnell J.E. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 1995, 64:621-651.
29. Stark G.R., Kerr I.M., Williams B.R., Silverman R.H., Schreiber R.D. How cells respond to interferons. Annu. Rev. Biochem. 1998, 67:227-264.
30. Subramaniam S., Kwon B., Beura L.K., Kuszynski C.A., Pattnaik A.K., Osorio F.A. Porcine reproductive and respiratory syndrome virus non-structural protein 1 suppresses tumor necrosis factor-alpha promoter activation by inhibiting NF-kappaB and Sp1. Virology 2010, 406:270-279.
31. Subramaniam S., Sur J.H., Kwon B., Pattnaik A.K., Osorio F.A. A virulent strain of porcine reproductive and respiratory syndrome virus does not up-regulate interleukin-10 levels in vitro or in vivo. Virus Res. 2011, 155:415-422.
32. Takaoka A., Yanai H. Interferon signalling network in innate defence. Cell. Microbiol. 2006, 8:907-922.
33. Wang R., Nan Y., Yu Y., Zhang Y.J. Porcine reproductive and respiratory syndrome virus Nsp1beta inhibits interferon-activated JAK/STAT signal transduction by inducing karyopherin-alpha1 degradation. J. Virol. 2013, 87:5219-5228.
34. Wensvoort G., Terpstra C., Pol J.M., ter Laak E.A., Bloemraad M., de Kluyver E.P., Kragten C., van Buiten L., den Besten A., Wagenaar F., et al. Mystery swine disease in The Netherlands: the isolation of Lelystad virus. Vet. Q. 1991, 13:121-130.
35. Xiao Z., Batista L., Dee S., Halbur P., Murtaugh M.P. The level of virus-specific T-cell and macrophage recruitment in porcine reproductive and respiratory syndrome virus infection in pigs is independent of virus load. J. Virol. 2004, 78:5923-5933.
36. Zhang Y., Sharma R.D., Paul P.S. Monoclonal antibodies against conformationally dependent epitopes on porcine reproductive and respiratory syndrome virus. Vet. Microbiol. 1998, 63:125-136.