메뉴 건너뛰기




Volumn 19, Issue 9, 2013, Pages 683-688

Impairment of triptolide on liver mitochondria in isolated liver mitochondria and HL7702 cell line

Author keywords

hepatotoxicity; mitochondria; triptolide

Indexed keywords

5,5',6,6 -TETRACHLORO 1,1',3,3' TETRAETHYLBENZIMIDAZOLYLCARBOCYANINE IODIDE; FLUORESCENT DYE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; REACTIVE OXYGEN METABOLITE; TRIPTOLIDE; UNCLASSIFIED DRUG;

EID: 84883287682     PISSN: 16720415     EISSN: 19930402     Source Type: Journal    
DOI: 10.1007/s11655-012-1265-x     Document Type: Article
Times cited : (23)

References (26)
  • 1
    • 0025944587 scopus 로고
    • Effect of an extract of the Chinese herbal remedy Tripterygium wilfordii Hook F on human immune responsiveness
    • 10.1002/art.1780341011 1:STN:280:DyaK38%2FivFWjsg%3D%3D
    • Tao X, Davis LS, Lipsky PE. Effect of an extract of the Chinese herbal remedy Tripterygium wilfordii Hook F on human immune responsiveness. Arthrit Rheum 1991;34:1274-1281.
    • (1991) Arthrit Rheum , vol.34 , pp. 1274-1281
    • Tao, X.1    Davis, L.S.2    Lipsky, P.E.3
  • 2
    • 0033975554 scopus 로고    scopus 로고
    • The Chinese anti-inflammatory and immunosuppressive herbal remedy Tripterygium wilfordii Hook F
    • 10680192 10.1016/S0889-857X(05)70118-6 1:STN:280:DC%2BD3c7ksVCntg%3D%3D
    • Tao X, Lipsky PE. The Chinese anti-inflammatory and immunosuppressive herbal remedy Tripterygium wilfordii Hook F. Rheum Dis Clin North Am 2000;26:29-50, viii.
    • (2000) Rheum Dis Clin North Am , vol.26 , pp. 29-50
    • Tao, X.1    Lipsky, P.E.2
  • 3
    • 0026672991 scopus 로고
    • Inhibitory effects of dihydroagarofuran sesquiterpenes on Epstein-Barr virus activation
    • 1324784 10.1016/0304-3835(92)90208-D 1:CAS:528:DyaK3sXltFynuw%3D%3D
    • Takaishi Y, Ujita K, Tokuda H, Nishino H, Iwashima A, Fujita T. Inhibitory effects of dihydroagarofuran sesquiterpenes on Epstein-Barr virus activation. Cancer Lett 1992;65:19-26.
    • (1992) Cancer Lett , vol.65 , pp. 19-26
    • Takaishi, Y.1    Ujita, K.2    Tokuda, H.3    Nishino, H.4    Iwashima, A.5    Fujita, T.6
  • 4
    • 0027381142 scopus 로고
    • Anti-inflammatory and immunosuppressive components of Tripterygium wilfordii Hook F
    • 1:CAS:528:DyaK2cXmvFSmug%3D%3D
    • Li XY. Anti-inflammatory and immunosuppressive components of Tripterygium wilfordii Hook F. Int J Immunother 1993;9:181-187.
    • (1993) Int J Immunother , vol.9 , pp. 181-187
    • Li, X.Y.1
  • 5
    • 33847313476 scopus 로고    scopus 로고
    • Medicated wine of Tripterygium wilfordii in treating rheumatoid arthritis in 392 patients
    • Yao W-C, Nian H-F. Medicated wine of Tripterygium wilfordii in treating rheumatoid arthritis in 392 patients. Pharmaceut Clin Res (Chin) 2004;23:35-37.
    • (2004) Pharmaceut Clin Res (Chin) , vol.23 , pp. 35-37
    • Yao, W.-C.1    Nian, H.-F.2
  • 6
    • 0031024058 scopus 로고    scopus 로고
    • Evaluation of the mutagenic, cytotoxic, and antitumor potential of triptolide, a highly oxygenated diterpene isolated from Tripterygium wilfordii
    • 9029176 10.1016/S0304-3835(96)04554-5
    • Shamon LA, Pezzuto JM, Graves JM, Mehta RR, Wangcharoentrakul S, Sangsuwan R, et al. Evaluation of the mutagenic, cytotoxic, and antitumor potential of triptolide, a highly oxygenated diterpene isolated from Tripterygium wilfordii. Cancer Lett 1997;112:113-117.
    • (1997) Cancer Lett , vol.112 , pp. 113-117
    • Shamon, L.A.1    Pezzuto, J.M.2    Graves, J.M.3    Mehta, R.R.4    Wangcharoentrakul, S.5    Sangsuwan, R.6
  • 7
    • 0026297544 scopus 로고
    • Screening of active anti-inflammatory, immunosuppressive and antifertility components from Tripterygium wilfordii. IV. A comparison of the male antifertility activities of 7 diterpene lactone epoxide compounds
    • 1:CAS:528:DyaK38Xlt1Cktbo%3D
    • Zheng J. Screening of active anti-inflammatory, immunosuppressive and antifertility components from Tripterygium wilfordii. IV. A comparison of the male antifertility activities of 7 diterpene lactone epoxide compounds. Acta Acad Med Sin (Chin) 1991;13:398-403.
    • (1991) Acta Acad Med Sin (Chin) , vol.13 , pp. 398-403
    • Zheng, J.1
  • 8
    • 0026271754 scopus 로고
    • Screening of active anti-inflammatory, immunosuppressive and antifertility components of Tripterygium wilfordii. III. A comparison of the antiinflammatory and immunosuppressive activities of 7 diterpene lactone epoxide compounds in vivo
    • 1:CAS:528:DyaK38XkvVejurs%3D
    • Zheng J. Screening of active anti-inflammatory, immunosuppressive and antifertility components of Tripterygium wilfordii. III. A comparison of the antiinflammatory and immunosuppressive activities of 7 diterpene lactone epoxide compounds in vivo. Acta Acad Med Sin (Chin) 1991;13:391-397.
    • (1991) Acta Acad Med Sin (Chin) , vol.13 , pp. 391-397
    • Zheng, J.1
  • 9
    • 0028962950 scopus 로고
    • The identity of immunosuppressive components of the ethyl acetate extract and chloroform methanol extract (T2) of Tripterygium wilfordii Hook F
    • 7891348 1:CAS:528:DyaK2MXktl2ktr0%3D
    • Tao X, Cai JJ, Lipsky PE. The identity of immunosuppressive components of the ethyl acetate extract and chloroform methanol extract (T2) of Tripterygium wilfordii Hook F. J Pharmacol Exp Ther 1995;272:1305-1312.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 1305-1312
    • Tao, X.1    Cai, J.J.2    Lipsky, P.E.3
  • 10
    • 0031982941 scopus 로고    scopus 로고
    • Effects of Tripterygium wilfordii Hook F extracts on induction of cyclooxygenase 2 activity and prostaglandin E2 production
    • 10.1002/1529-0131(199801)41:1<130: AID-ART16>3.0.CO;2-4 1:CAS:528:DyaK1cXmslyktQ%3D%3D
    • Tao X, Schulze-Koops H, Ma L, Cai J, Mao Y, Lipsky PE. Effects of Tripterygium wilfordii Hook F extracts on induction of cyclooxygenase 2 activity and prostaglandin E2 production. Arthrit Rheum 1998;41:130-138.
    • (1998) Arthrit Rheum , vol.41 , pp. 130-138
    • Tao, X.1    Schulze-Koops, H.2    Ma, L.3    Cai, J.4    Mao, Y.5    Lipsky, P.E.6
  • 11
    • 0035015065 scopus 로고    scopus 로고
    • Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii
    • 11374948 10.1021/np000504a 1:CAS:528:DC%2BD3MXisl2rt7g%3D
    • Duan H, Takaishi Y, Momota H, Ohmoto Y, Taki T, Jia Y, et al. Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii. J Nat Prod 2001;64:582-587.
    • (2001) J Nat Prod , vol.64 , pp. 582-587
    • Duan, H.1    Takaishi, Y.2    Momota, H.3    Ohmoto, Y.4    Taki, T.5    Jia, Y.6
  • 12
    • 0035478094 scopus 로고    scopus 로고
    • Immunosuppressive terpenoids from extracts of Tripterygium wilfordii
    • 10.1016/S0040-4020(01)00724-4 1:CAS:528:DC%2BD3MXntV2hurk%3D
    • Duan H, Takaishi Y, Momota H, Ohmoto Y, Taki T, Tori M, et al. Immunosuppressive terpenoids from extracts of Tripterygium wilfordii. Tetrahedron 2001;57:8413-8424.
    • (2001) Tetrahedron , vol.57 , pp. 8413-8424
    • Duan, H.1    Takaishi, Y.2    Momota, H.3    Ohmoto, Y.4    Taki, T.5    Tori, M.6
  • 13
    • 33847278423 scopus 로고    scopus 로고
    • Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)
    • 17250858 10.1016/j.phytochem.2006.11.029 1:CAS:528:DC%2BD2sXisVWht74%3D
    • Brinker AM, Ma J, Lipsky PE, Raskin I. Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae). Phytochemistry 2007;68:732-766.
    • (2007) Phytochemistry , vol.68 , pp. 732-766
    • Brinker, A.M.1    Ma, J.2    Lipsky, P.E.3    Raskin, I.4
  • 14
    • 27744449388 scopus 로고    scopus 로고
    • Effect of triptolide on urinary monocyte chemottractant protein-1 in patients with diabetic nephropathy
    • 1:CAS:528:DC%2BD28XjvFant7g%3D
    • Song HX, Gong J, Chen W. Effect of triptolide on urinary monocyte chemottractant protein-1 in patients with diabetic nephropathy. Chin J Integr Tradit West Med (Chin) 2005;25:416-418.
    • (2005) Chin J Integr Tradit West Med (Chin) , vol.25 , pp. 416-418
    • Song, H.X.1    Gong, J.2    Chen, W.3
  • 15
    • 15044342230 scopus 로고    scopus 로고
    • Herbal treatment for renal diseases
    • 15726219 1:STN:280:DC%2BD2M%2FpsVyrug%3D%3D
    • Peng A, Gu Y, Lin SY. Herbal treatment for renal diseases. Ann Acad Med Singapore 2005;34:44-51.
    • (2005) Ann Acad Med Singapore , vol.34 , pp. 44-51
    • Peng, A.1    Gu, Y.2    Lin, S.Y.3
  • 16
    • 22144466511 scopus 로고    scopus 로고
    • Clinical observation on effect of triptolide tablet in treating patients with psoriasis vulgaris
    • 16150204 10.1007/BF02836473
    • Wu SX, Guo NR. Clinical observation on effect of triptolide tablet in treating patients with psoriasis vulgaris. Chin J Integr Med 2005;11:147-148.
    • (2005) Chin J Integr Med , vol.11 , pp. 147-148
    • Wu, S.X.1    Guo, N.R.2
  • 17
    • 41849148999 scopus 로고    scopus 로고
    • Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells
    • 18379047 10.1248/bpb.31.592 1:CAS:528:DC%2BD1cXmtlakurs%3D
    • Yao J, Jiang Z, Duan W, Huang J, Zhang L, Hu L, et al. Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells. Biol Pharm Bull 2008;31:592-597.
    • (2008) Biol Pharm Bull , vol.31 , pp. 592-597
    • Yao, J.1    Jiang, Z.2    Duan, W.3    Huang, J.4    Zhang, L.5    Hu, L.6
  • 18
    • 67349149121 scopus 로고    scopus 로고
    • Caspase 3 is involved in the apoptosis induced by triptolide in HK-2 cells
    • 19233258 10.1016/j.tiv.2009.01.021 1:CAS:528:DC%2BD1MXmtFert70%3D
    • Shu B, Duan W, Yao J, Huang J, Jiang Z, Zhang L. Caspase 3 is involved in the apoptosis induced by triptolide in HK-2 cells. Toxicol In Vitro 2009;23:598-602.
    • (2009) Toxicol in Vitro , vol.23 , pp. 598-602
    • Shu, B.1    Duan, W.2    Yao, J.3    Huang, J.4    Jiang, Z.5    Zhang, L.6
  • 19
    • 77951297155 scopus 로고    scopus 로고
    • Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats
    • 20223271 10.1016/j.tox.2010.03.004 1:CAS:528:DC%2BC3cXks1WjtLc%3D
    • Liu L, Jiang Z, Liu J, Huang X, Wang T, Zhang Y, et al. Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats. Toxicology 2010;271:57-63.
    • (2010) Toxicology , vol.271 , pp. 57-63
    • Liu, L.1    Jiang, Z.2    Liu, J.3    Huang, X.4    Wang, T.5    Zhang, Y.6
  • 20
    • 58149215950 scopus 로고    scopus 로고
    • Male reproductive toxicity and toxicokinetics of triptolide in rats
    • 19202740 1:CAS:528:DC%2BD1MXhtVKrtr4%3D
    • Ni B, Jiang Z, Huang X, Xu F, Zhang R, Zhang Z, et al. Male reproductive toxicity and toxicokinetics of triptolide in rats. Arzneimittelforschung 2008;58:673-680.
    • (2008) Arzneimittelforschung , vol.58 , pp. 673-680
    • Ni, B.1    Jiang, Z.2    Huang, X.3    Xu, F.4    Zhang, R.5    Zhang, Z.6
  • 21
    • 57349085059 scopus 로고    scopus 로고
    • In vitro and in silico approaches for analyzing the toxicological effect of triptolide on cx43 in sertoli cells
    • 20020930 10.1080/15376510802192882 1:CAS:528:DC%2BD1cXhtlCksLnM
    • Ni B, Zhu T, Jiang Z, Zhang R, Zhang T, Zhang L. In vitro and in silico approaches for analyzing the toxicological effect of triptolide on cx43 in sertoli cells. Toxicol Mech Methods 2008;18:717-724.
    • (2008) Toxicol Mech Methods , vol.18 , pp. 717-724
    • Ni, B.1    Zhu, T.2    Jiang, Z.3    Zhang, R.4    Zhang, T.5    Zhang, L.6
  • 22
    • 0041342015 scopus 로고    scopus 로고
    • Drug-induced hepatotoxicity
    • 12890847 10.1056/NEJMra021844 1:CAS:528:DC%2BD3sXms1Ogs78%3D
    • Lee WM. Drug-induced hepatotoxicity. N Engl J Med 2003;349:474-485.
    • (2003) N Engl J Med , vol.349 , pp. 474-485
    • Lee, W.M.1
  • 24
    • 0029127584 scopus 로고
    • Inhibition of mitochondrial betaoxidation as a mechanism of hepatotoxicity
    • 7494860 10.1016/0163-7258(95)00012-6 1:CAS:528:DyaK2MXnvVKrs78%3D
    • Fromenty B, Pessayre D. Inhibition of mitochondrial betaoxidation as a mechanism of hepatotoxicity. Pharmacol Ther 1995;67:101-154.
    • (1995) Pharmacol Ther , vol.67 , pp. 101-154
    • Fromenty, B.1    Pessayre, D.2
  • 25
    • 0033501084 scopus 로고    scopus 로고
    • Hepatotoxicity due to mitochondrial dysfunction
    • 10811531 10.1023/A:1007649815992 1:CAS:528:DC%2BD3cXjslWitrk%3D
    • Pessayre D, Mansouri A, Haouzi D, Fromenty B. Hepatotoxicity due to mitochondrial dysfunction. Cell Biol Toxicol 1999;15:367-373.
    • (1999) Cell Biol Toxicol , vol.15 , pp. 367-373
    • Pessayre, D.1    Mansouri, A.2    Haouzi, D.3    Fromenty, B.4
  • 26
    • 84934440377 scopus 로고    scopus 로고
    • Triptolide alters mitochondrial functions
    • 17727258 10.1007/978-0-387-71764-7-19 1:CAS:528:DC%2BC3cXhsFKisbzI
    • Su Y, Yang S, Xiao Z, Wang W, Okunieff P, Zhang L. Triptolide alters mitochondrial functions. Adv Exp Med Biol 2007;599:139-146.
    • (2007) Adv Exp Med Biol , vol.599 , pp. 139-146
    • Su, Y.1    Yang, S.2    Xiao, Z.3    Wang, W.4    Okunieff, P.5    Zhang, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.