Enantiomeric separation of amlodipine and its two chiral impurities by nano-liquid chromatography and capillary electrochromatography using a chiral stationary phase based on cellulose tris(4-chloro-3-methylphenylcarbamate)

Electrophoresis

Volumn 34, Issue 17, 2013, Pages 2593-2600

  Auditore, Roberta ^a   Santagati, Natale A ^a   Aturki, Zeineb ^b   Fanali, Salvatore ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b CNR Consiglio Nazionale delle Ricerche   (Italy)

Author keywords

Amlodipine; Capillary electrochromatography; Impurities; Nano liquid chromatography; Polysaccharide based chiral stationary phase

Indexed keywords

CELLULOSE; CHIRALITY; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY;

AMLODIPINE; BUFFER PH; CAPILLARY ELECTROCHROMATOGRAPHY; CHIRAL SEPARATIONS; CHIRAL STATIONARY PHASE; ENANTIOMERIC SEPARATION; NANO LIQUID CHROMATOGRAPHY; NANO-LC; PHASE BASED; POLYSACCHARIDE-BASED CHIRAL STATIONARY PHASIS;

ENANTIOMERS;

AMLODIPINE BESYLATE; CELLULOSE TRIS(4 CHLORO 3 METHYLPHENYLCARBAMATE); POLYSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY ELECTROCHROMATOGRAPHY; CHIRALITY; CONCENTRATION RESPONSE; DRUG IMPURITY; ENANTIOMER; NANOLIQUID CHROMATOGRAPHY; PH; PHASE TRANSITION; SEPARATION TECHNIQUE;

AMLODIPINE; CAPILLARY ELECTROCHROMATOGRAPHY; IMPURITIES; NANO-LIQUID CHROMATOGRAPHY; POLYSACCHARIDE-BASED CHIRAL STATIONARY PHASE;

AMLODIPINE; CAPILLARY ELECTROCHROMATOGRAPHY; CELLULOSE; CHROMATOGRAPHY, LIQUID; LIMIT OF DETECTION; LINEAR MODELS; NANOTECHNOLOGY; PHENYLCARBAMATES; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM;

EID: 84883274280     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201300157     Document Type: Article

References (34)

1. De Camp, W. H., J. Pharm. Biomed. Anal. 1993, 11, 1167-1172.
2. Meredith, P. A., Elliott, H. L., Clin. Pharmacokinet. 1992, 22, 22-31.
3. Murdoch, D., Heel, R. C., Drugs, 1991, 41, 478-505.
4. Arrowsmith, J. E., Campbell, S. F., Cross, E., Stubbs, J. K., Burgers, R. A., Gardiner, D. G., Blackburn, R. A., J. Med. Chem. 1986, 29, 1696-1702.
5. Goldman, S., Stoltefuss, J., Born, L., J. Med. Chem. 1992, 35, 33-41.
6. Beresford, A. P., Macrae, P. V., Stopher, D. A., Wood, B. A., J. Chromatogr. 1987, 420, 178-183.
7. Lukša, J., Josič, Dj., Kremser, M., Kopitar, Z., Milutinovič, S., J. Chromatogr. B 1997, 703, 185-193.
8. Zhang, X. P., Loke, K. E., Mital, S., Chahwala, S., Hintze, T. H., J. Cardiovasc. Pharmcol. 2002, 39, 208-214.
9. Sudhakar, P., Nirmala, M., Moses Babu, J., Vyas, K., Madhusudan Reddy, G., Vijaya Bhaskar, B., Pratap Reddy, P., Mukkanti, K., J. Pharm. Biomed. Anal. 2006, 40, 605-613.
10. Žmitek, J., Grahek, R., Žižek, T., Furlan, B., Acta Chim. Slov. 2000, 47, 63-68.
11. Ananchenko, G., Novakovic, J., Lewis, J., in: Brittain, H. G. (Ed.), Profiles of Drug Substances, Excipients and Related Methodology, Vol. 37, Academic Press, New York 2012, pp. 31-77.
12. Boatto, G., Nieddu, M., Faedda, M. V., De Caprariis P., Chirality 2003, 15, 494-497.
13. Gholami, M., Ghassempour, A., Alizadeh, R., Aboul-Enein, H. Y., J. Sep. Sci. 2009, 32, 918-922.
14. Josefsson, M., Norlander, B., J. Pharm. Biomed. Anal. 1996, 15, 267-277.
15. Streel, B., Lainé, C. Zimmer, C. Sibenaler, R., Ceccato, A., J. Biochem. Biophys. Methods 2002, 54, 357-368.
16. Dossou, K. S. S., Edorh, P. A., Chiap, P., Chankvetadze, B., Servais, A. C., Fillet, M., Crommen, J., J. Sep. Sci. 2011, 34, 1772-1780.
17. Jibuti, G., Mskhiladze, A., Takaishvili, N., Karchkhadze, M., Chankvetadze, L., Farkas, T. Chankvetadze, B., J. Sep. Sci. 2012, 35, 2529-2537.
18. Christians, T., Diewald, D., Wessler C., Otte, Y., Lehmann, J., Holzgrabe, U., J. Chromatogr. A 1999, 853, 455-460.
19. Wang, R., Jia, Z., Fan, J. J., Chen, L. R., Xie, H., Ma, J., Ge, X., Zhang, Q., Ao, Y., Wang, J., Chromatographia 2007, 65, 575-579.
20. Fakhari, A. R., Nojavan, S., Haghgoo, S., Mohammadi, A., Electrophoresis 2008, 29, 4583-4592.
21. Preinerstorfer, B. Lämmerhofer, M., Electrophoresis 2007, 28, 2527-2565.
22. Preinerstorfer, B. Lämmerhofer, M., Lindner, W., Electrophoresis 2009, 30, 100-132.
23. Hernández-Borges, J., Aturki, Z., Rocco, A., Fanali, S., J. Sep. Sci. 2007, 30, 1589-1610.
24. Scriba, G. K. E., J. Pharm. Biomed. Anal. 2011, 55, 688-701.
25. Yashima, E., J. Chromatogr. A 2001, 906, 105-125.
26. Chankvetadze, B., J. Chromatogr. A 2012, 1269, 26-51.
27. Zhou, L., Welch, C., Lee, C., Gong, X., Antonucci, V., Ge, Z., J. Pharm. Biomed. Anal. 2009, 49, 964-969.
28. Younes, A. A., Mangelings, D., Vander Heyden, Y., J. Pharm. Biomed. Anal. 2011, 56, 521-537.
29. Dossou, K. S. S., Chiap, P., Servais, A. C., Crommen, J., J. Sep. Sci. 2011, 34, 617-622.
30. Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A. C., Fillet, M., Crommen, J., J. Sep. Sci. 2010, 33, 1699-1707.
31. Hendrickx, A., Mangelings, D, Chankvetadze, B., Vander Heyden, Y., Electrophoresis 2010, 31, 3207-3216.
32. Dominguez-Vega, E., Crego, A. L., Lomsadze, K., Chankvetadze, B., Marina, M. L., Electrophoresis 2011, 32, 2700-2707.
33. Pérez-Fernández, V., Dominguez-Vega, E., Chankvetadze, B., Crego, A-L., Angeles García, M., Marina, M. L., J. Chromatogr. A 2012, 1234, 22-31.
34. Fanali, S., D'Orazio, G., Lomasadze, B., Chankvetadze, B., J. Chromatogr. B 2008, 875, 296-303.