HPLC separation of dihydropyridine derivatives enantiomers with emphasis on elution order using polysaccharide-based chiral columns

Journal of Separation Science

Volumn 35, Issue 19, 2012, Pages 2529-2537

  Jibuti, George ^a   Mskhiladze, Antonina ^b   Takaishvili, Nino ^a   Karchkhadze, Marina ^a   Chankvetadze, Lali ^a   Farkas, Tivadar ^c   Chankvetadze, Bezhan ^a  

^a TBILISI STATE UNIVERSITY   (Georgia)

^b SOKHUMI STATE UNIVERSITY   (Georgia)

^c PHENOMENEX INC   (United States)

Author keywords

Chiral dihydropyridine derivatives; Enantiomer elution order; Enantiomer separation; High performance liquid chromatography; Polysaccharide based chiral stationary phases

Indexed keywords

AMLODIPINE; ANALYTES; CHIRAL COLUMN; CHIRAL HPLC; CHIRAL STATIONARY PHASIS; DIETHYLAMINES; DIHYDROPYRIDINES; ELUENTS; ELUTION ORDER; ENANTIOMER SEPARATION; HPLC SEPARATION; LOW WATER-CONTENT; MOBILE PHASE; MOBILE PHASIS; MOBILE-PHASE COMPOSITION; RETENTION FACTORS; REVERSED PHASE;

ACETONITRILE; CHIRALITY; FORMIC ACID; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PYRIDINE; SEPARATION;

ENANTIOMERS;

ACETONITRILE; AMLODIPINE; DIHYDROPYRIDINE DERIVATIVE; FORMIC ACID;

ARTICLE; CONFORMATION; CONTROLLED STUDY; ELUTION; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; HYDROPHILIC INTERACTION CHROMATOGRAPHY; PRIORITY JOURNAL; SIGNAL NOISE RATIO; WATER CONTENT;

EID: 84866704376     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201200443     Document Type: Article

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