Transcription factor Nrf2 protects renal dopamine D1 receptor function during oxidative stress

Hypertension

Volumn 62, Issue 3, 2013, Pages 512-517

  Banday, Anees Ahmad ^a   Lokhandwala, Mustafa F ^a  

^a 521 S and R 2 Building ^*  (United States)

Author keywords

hypertension; Na K ATPase; NHE3; nuclear factor B; sulforaphane

Indexed keywords

DOPAMINE 1 RECEPTOR; GLUTATHIONE TRANSFERASE; HEME OXYGENASE 1; I KAPPA B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SODIUM; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DOWN REGULATION; ENZYME ACTIVATION; HYPERTENSION; KIDNEY PROXIMAL TUBULE; MALE; NATRIURESIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; RENAL PROTECTION; SIGNAL TRANSDUCTION; SODIUM EXCRETION; SODIUM URINE LEVEL;

HYPERTENSION; NA/K-ATPASE; NHE3; NUCLEAR FACTOR-ΚB; SULFORAPHANE;

2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE; ANIMALS; DOPAMINE AGONISTS; KIDNEY; MALE; NATRIURESIS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; SODIUM-HYDROGEN ANTIPORTER; SODIUM-POTASSIUM-EXCHANGING ATPASE; THIOCYANATES;

EID: 84883273201     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.01358     Document Type: Article

References (36)

1. Sanada H, Jones JE, Jose PA. Genetics of salt-sensitive hypertension. Curr Hypertens Rep. 2011;13:55-66.
2. Wang X, Armando I, Upadhyay K, Pascua A, Jose PA. The regulation of proximal tubular salt transport in hypertension: An update. Curr Opin Nephrol Hypertens. 2009;18:412-420.
3. Zeng C, Jose PA. Dopamine receptors: Important antihypertensive counterbalance against hypertensive factors. Hypertension. 2011;57:11-17.
4. Wang X, Villar VA, Armando I, Eisner GM, Felder RA, Jose PA. Dopamine, kidney, and hypertension: Studies in dopamine receptor knockout mice. Pediatr Nephrol. 2008;23:2131-2146.
5. Zeng C, Armando I, Luo Y, Eisner GM, Felder RA, Jose PA. Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: Studies in dopamine receptor knockout mice. Am J Physiol Heart Circ Physiol. 2008;294:H551-H569.
6. Zeng C, Eisner GM, Felder RA, Jose PA. Dopamine receptor and hypertension. Curr Med Chem Cardiovasc Hematol Agents. 2005;3:69-77.
7. Zeng C, Felder RA, Jose PA. A new approach for treatment of hypertension: Modifying D1 dopamine receptor function. Cardiovasc Hematol Agents Med Chem. 2006;4:369-377.
8. Zeng C, Sanada H, Watanabe H, Eisner GM, Felder RA, Jose PA. Functional genomics of the dopaminergic system in hypertension. Physiol Genomics. 2004;19:233-246.
9. Zeng C, Zhang M, Asico LD, Eisner GM, Jose PA. The dopaminergic system in hypertension. Clin Sci (Lond). 2007;112:583-597.
10. Luippold G, Zimmermann C, Mai M, Kloor D, Starck D, Gross G, Mühlbauer B. Dopamine D(3) receptors and salt-dependent hypertension. J Am Soc Nephrol. 2001;12:2272-2279.
11. Albrecht FE, Drago J, Felder RA, Printz MP, Eisner GM, Robillard JE, Sibley DR, Westphal HJ, Jose PA. Role of the D1A dopamine receptor in the pathogenesis of genetic hypertension. J Clin Invest. 1996;97:2283-2288.
12. Chugh G, Lokhandwala MF, Asghar M. Altered functioning of both renal dopamine D1 and angiotensin II type 1 receptors causes hypertension in old rats. Hypertension. 2012;59:1029-1036.
13. Banday AA, Marwaha A, Tallam LS, Lokhandwala MF. Tempol reduces oxidative stress, improves insulin sensitivity, decreases renal dopamine D1 receptor hyperphosphorylation, and restores D1 receptor-G-protein coupling and function in obese Zucker rats. Diabetes. 2005;54:2219-2226.
14. Shin Y, White BH, Uh M, Sidhu A. Modulation of D1-like dopamine receptor function by aldehydic products of lipid peroxidation. Brain Res. 2003;968:102-113.
15. Fardoun RZ, Asghar M, Lokhandwala M. Role of oxidative stress in defective renal dopamine D1 receptor-G protein coupling and function in old Fischer 344 rats. Am J Physiol Renal Physiol. 2006;291:F945-F951.
16. Banday AA, Fazili FR, Marwaha A, Lokhandwala MF. Mitogen-activated protein kinase upregulation reduces renal D1 receptor affinity and G-protein coupling in obese rats. Kidney Int. 2007;71:397-406.
17. Zeng C, Villar VA, Eisner GM, Williams SM, Felder RA, Jose PA. G protein-coupled receptor kinase 4: Role in blood pressure regulation. Hypertension. 2008;51:1449-1455.
18. Rankin ML, Sibley DR. Constitutive phosphorylation by protein kinase C regulates D1 dopamine receptor signaling. J Neurochem. 2010;115:1655-1667.
19. Banday AA, Lokhandwala MF. Oxidative stress reduces renal dopamine D1 receptor-Gq/11alpha G protein-phospholipase C signaling involving G protein-coupled receptor kinase 2. Am J Physiol Renal Physiol. 2007;293:F306-F315.
20. Ferretti G, Bacchetti T, Masciangelo S, Saturni L. Celiac disease, inflammation and oxidative damage: A nutrigenetic approach. Nutrients. 2012;4:243-257.
21. Leonardo CC, Doré S. Dietary flavonoids are neuroprotective through Nrf2-coordinated induction of endogenous cytoprotective proteins. Nutr Neurosci. 2011;14:226-236.
22. Pastore A, Piemonte F. S-Glutathionylation signaling in cell biology: Progress and prospects. Eur J Pharm Sci. 2012;46:279-292.
23. Banday AA, Lokhandwala MF. Inhibition of natriuretic factors increases blood pressure in rats. Am J Physiol Renal Physiol. 2009;297:F397-F402.
24. Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem. 1978;86:271-278.
25. Javkhedkar AA, Lokhandwala MF, Banday AA. Defective nitric oxide production impairs angiotensin II-induced Na-K-ATPase regulation in spontaneously hypertensive rats. Am J Physiol Renal Physiol. 2012;302:F47-F51.
26. Marwaha A, Banday AA, Lokhandwala MF. Reduced renal dopamine D1 receptor function in streptozotocin-induced diabetic rats. Am J Physiol Renal Physiol. 2004;286:F451-F457.
27. Banday AA, Lokhandwala MF. Oxidative stress-induced renal angiotensin AT1 receptor upregulation causes increased stimulation of sodium transporters and hypertension. Am J Physiol Renal Physiol. 2008;295:F698-F706.
28. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680-685.
29. Montezano AC, Touyz RM. Molecular mechanisms of hypertension-reactive oxygen species and antioxidants: A basic science update for the clinician. Can J Cardiol. 2012;28:288-295.
30. Khan SR. Is oxidative stress, a link between nephrolithiasis and obesity, hypertension, diabetes, chronic kidney disease, metabolic syndromé Urol Res. 2012;40:95-112.
31. Asghar M, Banday AA, Fardoun RZ, Lokhandwala MF. Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2. Free Radic Biol Med. 2006;40:13-20.
32. Baker RG, Hayden MS, Ghosh S. NF-kappaB, inflammation, and metabolic disease. Cell Metab. 2011;13:11-22.
33. Diaz-Meco MT, Moscat J. The atypical PKCs in inflammation: NF-kappaB and beyond. Immunol Rev. 2012;246:154-167.
34. Sedaghat K, Tiberi M. Cytoplasmic tail of D1 dopaminergic receptor differentially regulates desensitization and phosphorylation by G proteincoupled receptor kinase 2 and 3. Cell Signal. 2011;23:180-192.
35. Kansanen E, Jyrkkänen HK, Levonen AL. Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids. Free Radic Biol Med. 2012;52:973-982.
36. Yu M, Li H, Liu Q, Liu F, Tang L, Li C, Yuan Y, Zhan Y, Xu W, Li W, Chen H, Ge C, Wang J, Yang X. Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway. Cell Signal. 2011;23:883-892.