Rosuvastatin suppresses platelet derived growth factor-BB-induced vascular smooth muscle cell proliferation and migration via the MAPK signaling pathway

Experimental and Therapeutic Medicine

Volumn 6, Issue 4, 2013, Pages 899-903

  Gan, Jianting ^a   Li, Ping ^a   Wang, Zhengdong ^a   Chen, Jian ^a   Liang, Xiangwen ^a   Liu, Ming ^a   Xie, Wenchao ^a   Yin, Ruixing ^b   Huang, Feng ^b  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Migration; Mitogen activated protein kinase; Platelet derived growth factor; Proliferation; Rosuvastatin; Vascular smooth muscle cell

Indexed keywords

GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PLATELET DERIVED GROWTH FACTOR BB; ROSUVASTATIN;

ANIMAL CELL; ARTICLE; CELL DEDIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; HEART CELL CULTURE; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

EID: 84883245238     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2013.1265     Document Type: Article

References (26)

1. Doran AC, Meller N and McNamara CA: Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler Thromb Vasc Biol 28: 812-819, 2008.
2. Hao H, Gabbiani G and Bochaton-Piallat ML: Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development. Arterioscler Thromb Vasc Biol 23: 1510-1520, 2003.
3. Obata JE, Nakamura T, Kitta Y, et al: In-stent restenosis is inhibited in a bare metal stent implanted distal to a sirolimus-eluting stent to treat a long de novo coronary lesion with small distal vessel diameter. Catheter Cardiovasc Interv: Feb 4, 2013 (Epub ahead of print).
4. Mazurova VV, Sukhorukov OE and Zakharova OV: Comparing moderately late results of the application of stents coated with a medicinal antiproliferative agent for the treatment of patients with various forms of coronary heart disease: their efficacy and safety. Klin Med (Mosk) 90: 30-35, 2012 (In Russian).
5. Babapulle MN and Eisenberg MJ: Coated stents for the prevention of restenosis: part I. Circulation 106: 2734-2740, 2002.
6. Zhao Y, Liu YX, Xie SL, Deng BQ, Wang JF and Nie RQ: Increased expression of granulocyte colony-stimulating factor mediates mesenchymal stem cells recruitment after vascular injury. Chin Med J (Engl) 124: 4286-4292, 2011.
7. Niida T, Isoda K, Kitagaki M, et al: IκBNS regulates interleukin-6 production and inhibits neointimal formation after vascular injury in mice. Cardiovasc Res 93: 371-379, 2012.
8. Park ES, Kang SI, Yoo KD, et al: Camptothecin inhibits platelet-derived growth factor-BB-induced proliferation of rat aortic vascular smooth muscle cells through inhibition of PI3K/Akt signaling pathway. Exp Cell Res 319: 982-991, 2013.
9. Sun L, Zhao R, Zhang L, et al: Salvianolic acid A inhibits PDGF-BB induced vascular smooth muscle cell migration and proliferation while does not constrain endothelial cell proliferation and nitric oxide biosynthesis. Molecules 17: 3333-3347, 2012.
10. Sohda T, Iwata K, Hirano G, et al: 3-Hydroxyl-3-methylglutaryl-coenzyme A reductase is up regulated in hepatocellular carcinoma associated with paraneoplastic hypercholesterolemia. Med Mol Morphol: April 3, 2013.
11. DiNicolantonio JJ, Lavie CJ, Serebruany VL and O'Keefe JH: Statin wars: the heavyweight match - atorvastatin versus rosuvastatin for the treatment of atherosclerosis, heart failure, and chronic kidney disease. Postgrad Med 125: 7-16, 2013.
12. Abel T and Fehér J: Role of rosuvastatin in current lipid-lowering therapy. Orv Hetil 151: 1424-1428, 2010 (In Hungarian).
13. Waters DD: Exploring new indications for statins beyond atherosclerosis: Successes and setbacks. J Cardiol 55: 155-162, 2010.
14. Zhu L, Hao Y, Guan H, Cui C, Tian S, Yang D, Wang X, Zhang S, Wang L and Jiang H: Effect of sinomenine on vascular smooth muscle cell dedifferentiation and neointima formation after vascular injury in mice. Mol Cell Biochem 373: 53-62, 2013.
15. Iida M, Tanabe K, Matsushima-Nishiwaki R, Kozawa O and Iida H: Adenosine monophosphate-activated protein kinase regulates platelet-derived growth factor-BB-induced vascular smooth muscle cell migration. Arch Biochem Biophys 530: 83-92, 2013.
16. Li P, Liu Y, Yi B, et al: MicroRNA-638 is highly expressed in human vascular smooth muscle cells and inhibits PDGF-BB-induced cell proliferation and migration through targeting orphan nuclear receptor NOR1. Cardiovasc Res 99: 185-193, 2013.
17. Park ES, Lee KP, Jung SH, et al: Compound K, an intestinal metabolite of ginsenosides, inhibits PDGF-BB-induced VSMC proliferation and migration through G1 arrest and attenuates neointimal hyperplasia after arterial injury. Atherosclerosis 228: 53-60, 2013.
18. Yi N, Chen SY, Ma A, et al: Tunicamycin inhibits PDGF-BB-induced proliferation and migration of vascular smooth muscle cells through induction of HO-1. Anat Rec (Hoboken) 295: 1462-1472, 2012.
19. Gao J, Ding F, Liu Q and Yao Y: Knockdown of MACC1 expression suppressed hepatocellular carcinoma cell migration and invasion and inhibited expression of MMP2 and MMP9. Mol Cell Biochem 376: 21-32, 2013.
20. Mishra A, Srivastava A, Mittal T, Garg N and Mittal B: Association of matrix metalloproteinases (MMP2, MMP7 and MMP9) genetic variants with left ventricular dysfunction in coronary artery disease patients. Clin Chim Acta 413: 1668-1674, 2012.
21. Deatrick KB, Luke CE, Elfline MA, et al: The effect of matrix metalloproteinase 2 and matrix metalloproteinase 2/9 deletion in experimental post-thrombotic vein wall remodeling. J Vasc Surg: Mar 9, 2013 (Epub ahead of print).
22. Halade GV, Jin YF and Lindsey ML: Matrix metalloproteinase (MMP)-9: a proximal biomarker for cardiac remodeling and a distal biomarker for inflammation. Pharmacol Ther 139: 32-40, 2013.
23. Yang JL, Lin JH, Weng SW, et al: Crude extract of Euphorbia formosana inhibits the migration and invasion of DU145 human prostate cancer cells: The role of matrix metalloproteinase-2/9 inhibition via the MAPK signaling pathway. Mol Med Rep 7: 1403-1408, 2013.
24. Santarpia L, Lippman SM and El-Naggar AK: Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy. Expert Opin Ther Targets 16: 103-119, 2012.
25. Zhao Y, Lv M, Lin H, et al: ROCK1 induces ERK nuclear translocation in PDGF-BB-stimulated migration of rat vascular smooth muscle cells. IUBMB Life 64: 194-202, 2012.
26. Zhu L, Guan H, Cui C, et al: Gastrodin inhibits cell proliferation in vascular smooth muscle cells and attenuates neointima formation in vivo. Int J Mol Med 30: 1034-1040, 2012.