Salvianolic acid a inhibits PDGF-BB induced vascular smooth muscle cell migration and proliferation while does not constrain endothelial cell proliferation and nitric oxide biosynthesis

Molecules

Volumn 17, Issue 3, 2012, Pages 3333-3347

  Sun, Lan ^a   Zhao, Rui ^a   Zhang, Li ^a   Zhang, Tiantai ^a   Xin, Wenyu ^a   Lan, Xi ^a   Huang, Chao ^a   Du, Guanhua ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Migration; Proliferation; Re endothelialization; Salvianolic A; Vascular smooth muscle cell

Indexed keywords

CAFFEIC ACID DERIVATIVE; CELL ADHESION MOLECULE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; LACTIC ACID DERIVATIVE; NITRIC OXIDE; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PLATELET-DERIVED GROWTH FACTOR BB; SALVIANOLIC ACID A;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENETICS; HUMAN; MALE; METABOLISM; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; SPRAGUE DAWLEY RAT; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR SMOOTH MUSCLE;

ANIMALS; CAFFEIC ACIDS; CELL ADHESION MOLECULES; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LACTATES; MALE; MAP KINASE SIGNALING SYSTEM; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PROTO-ONCOGENE PROTEINS C-SIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR;

EID: 84858965848     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17033333     Document Type: Article

References (30)

1. Berk, B. C. Vascular smooth muscle growth: Autocrine growth mechanisms. Physiol Rev. 2001, 81, 999-1030. (Pubitemid 32606665)
2. Levitzki, A. PDGF receptor kinase inhibitors for the treatment of restenosis. Cardiovasc. Res. 2005, 65, 581-586. (Pubitemid 40142661)
3. Zhan, Y.; Kim, S.; Izumi, Y.; Izumiya, Y.; Nakao, T.; Miyazaki, H.; Iwao, H. Role of JNK, p38, and ERK in platelet-derived growth factor-induced vascular proliferation, migration, and gene expression. Arterioscler. Thromb. Vasc. Biol. 2003, 23, 795-801. (Pubitemid 36566168)
4. Zheng, B.; Han, M.; Bernier, M.; Zhang, X. H.; Meng, F.; Miao, SB.; He, M.; Zhao, X. M.; Wen, J. K. Krüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor P-mediated, not by retinoic acid receptor α-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells. J. Biol. Chem. 2009, 284, 22773-22785.
5. Chao, J. I.; Su, W. C.; Liu, H. F. Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogenactivated protein kinase and AKT. Mol Cancer Ther. 2007, 6, 3039-3048.
6. Ho, J. H.; Hong, C. Y. Salvianolic acids: Small compounds with multiple mechanisms for cardiovascular protection. J. Biomed. Sci. 2011, 18, 30.
7. Pan, C. H.; Chen, C. W.; Sheu, M. J.; Wu, C. H. Salvianolic acid B inhibits SDF-1α-stimulated cell proliferation and migration of vascular smooth muscle cells by suppressing CXCR4 receptor. Vascul Pharmacol. 2012, 56, 98-105.
8. Yang, X. Y.; Sun, L.; Xu, P.; Gong, L. L.; Qiang, G. F.; Zhang, L.; Du, GH. Effects of salvianolic scid A on plantar microcirculation and peripheral nerve function in diabetic rats. Eur. J. Pharmacol. 2011, 665, 40-46.
9. Jiang, M.; Wang, X. Y.; Zhou, W. Y.; Li, J.; Wang, J.; Guo, L. P. Cerebral protection of salvianolic acid A by the inhibition of granulocyte adherence. Am. J. Chin. Med. 2011, 39, 111-120.
10. Pan, H.; Li, D.; Fang, F.; Chen, D.; Qi, L.; Zhang, R.; Xu, T.; Sun, H. Salvianolic acid a demonstrates cardioprotective effects in rat hearts and cardiomyocytes after ischemia/reperfusion injury. J. Cardiovasc. Pharmacol. 2011, 58, 535-542.
11. Heldin, C. H.; Westermark, B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev. 1999, 79, 1283-1316. (Pubitemid 29473317)
12. Yang, X.; Thomas, DP.; Zhang, X.; Culver, B. W.; Alexander, B. M.; Murdoch, W. J.; Rao, M. N.; Tulis, D. A.; Ren, J.; Sreejayan, N. Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation. Arterioscler. Thromb. Vasc. Biol 2006, 26, 85-90. (Pubitemid 43732232)
13. Lamy, S.; Beaulieu, E.; Labbé, D.; Bédard, V.; Moghrabi, A.; Barrette, S.; Gingras, D.; Béliveau, R. Delphinidin, a dietary anthocyanidin, inhibits platelet-derived growth factor ligand/receptor (PDGF/PDGFR) signaling. Carcinogenesis 2008, 29, 1033-1041. (Pubitemid 351982249)
14. Godichaud, S.; Si-Tayeb, K.; Augé, N.; Desmoulière, A.; Balabaud, C.; Payrastre, B.; Nègre-Salvayre, A.; Rosenbaum J. The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts. Int. J. Biochem. Cell Biol. 2006, 38, 629-637. (Pubitemid 43117586)
15. Chen, A.; Zhang, L. The antioxidant (-)-epigallocatechin-3-gallate inhibits rat hepatic stellate cell proliferation in vitro by blocking the tyrosine phosphorylation and reducing the gene expression of platelet-derived growth factor-beta receptor. J. Biol. Chem. 2003, 278, 23381-23389. (Pubitemid 36830154)
16. Ahn, H. Y.; Hadizadeh, K. R.; Seul, C.; Yun, Y. P.; Vetter, H.; Sachinidis, A. Epigallocathechin-3 gallate selectively inhibits the PDGFBB-induced intracellular signaling transduction pathway in vascular smooth muscle cells and inhibits transformation of sis-transfected NIH 3T3 fibroblasts and human glioblastoma cells (A172). Mol. Biol. Cell 1999, 10, 1093-1104. (Pubitemid 29193733)
17. Egozi, D.; Shapira, M.; Paor, G.; Ben-Izhak, O.; Skorecki, K.; Hershko, D. D. Regulation of the cell cycle inhibitor p27 and its ubiquitin ligase Skp2 in differentiation of human embryonic stem cells. FASEB J. 2007, 21, 2807-2817. (Pubitemid 47372748)
18. Claesson-Welsh, L. Platelet-derived growth factor receptor signals. J. Biol. Chem. 1994, 269, 32023-32026.
19. Hung, Y. C.; Wang, P. W.; Pan, T. L.; Bazylak, G.; Leu, Y. L. Proteomic screening of antioxidant effects exhibited by radix Salvia miltiorrhiza aqueous extract in cultured rat aortic smooth muscle cells under homocysteine treatment. J. Ethnopharmacol. 2009, 124, 463-474.
20. Lai, K.; Wang, H.; Lee, W. S.; Jain, M. K.; Lee, M. E.; Haber, E. Mitogenactivated protein kinase phosphatase-1 in rat arterial smooth muscle cell proliferation. J. Clin. Invest. 1996, 98, 1560-1567. (Pubitemid 26327865)
21. Pyles, J. M.; March, K. L.; Franklin, M.; Mehdi, K.; Wilensky, R. L.; Adam, L. P. Activation of MAP kinase in vivo follows balloon over stretch injury of porcine coronary and carotid arteries. Circ. Res. 1997, 81, 904-910. (Pubitemid 27514939)
22. Izumi, Y.; Kim, S.; Namba, M.; Yasumoto, H.; Miyazaki, H.; Hoshiga, M.; Kaneda, Y.; Morishita, R.; Zhan, Y.; Iwao, H. Gene transfer of dominant-negative mutants of extracellular signal-regulated kinase and c-Jun. NH2-terminal kinase prevents neointimal formation in balloon-injured rat artery. Circ. Res. 2001, 88, 1120-1126. (Pubitemid 34132511)
23. Picard, P.; Smith, P. J.; Monge, J. C.; Stewart, D. J. Expression of endothelial factors after arterial injury in the rat. J. Cardiovasc. Pharmacol. 1998, 31, S323-S327. (Pubitemid 128709940)
24. Versari, D.; Lerman, L. O.; Lerman, A. The importance of reendothelialization after arterial injury. Curr. Pharm. Des. 2007, 13, 1811-1824. (Pubitemid 46979717)
25. Institute of Laboratory Animal Resources (USA). Guide for the Care and Use of Laboratory Animals; National Academy Press: Washington, DC, USA, 1996.
26. Sun, L.; Zhang, T.; Yu, X.; Xin, W.; Lan, X.; Zhang, D.; Huang, C.; Du, G. Asymmetric dimethylarginine confers the communication between endothelial and smooth muscle cells and leads to VSMC migration through p38 and ERK1/2 signaling cascade. FEBS Lett. 2011, 585, 2727-2734.
27. Rothmeier, A. S.; Ischenko, I.; Joore, J.; Garczarczyk, D.; Fürst, R.; Bruns, C. J.; Vollmar, A. M.; Zahler, S. Investigation of the marine compound spongistatin 1 links the inhibition of PKC alpha translocation to nonmitotic effects of tubulin antagonism in angiogenesis. FASEB J. 2009, 23, 1127-1137.
28. Fürst, R.; Zirrgiebel, U.; Totzke, F.; Zahler, S.; Vollmar, A. M.; Koch, E. The Crataegus extract WS 1, 442 inhibits balloon catheter-induced intimal hyperplasia in the rat carotid artery by directly influencing PDGFR-beta. Atherosclerosis 2010, 211, 409-417.
29. Zargham, R.; Thibault, G. α8β1 Integrin expression in the rat carotid artery: Involvement in smooth muscle cell migration and neointima formation. Cardiovasc. Res. 2005, 65, 813-822. (Pubitemid 40249726)
30. Park, E. S.; Yoo, J. M.; Lim, Y.; Tudev, M.; Yoo, H. S.; Hong, J. T.; Yun, Y. P. Inhibitory effects of docetaxel on platelet-derived growth factor (PDGF)-BB-induced proliferation of vascular smooth muscle cells through blocking PDGF-receptor β phosphorylation. J. Pharmacol. Sci. 2011, 116, 204-213.