Surgical site infections in liver transplant recipients in the model for end-stage liver disease era: An analysis of the epidemiology, risk factors, and outcomes

Liver Transplantation

Volumn 19, Issue 9, 2013, Pages 1011-1019

  Freire, Maristela Pinheiro ^a   Soares Oshiro, Isabel C V ^a   Bonazzi, Patricia Rodrigues ^a   Guimarães, Thais ^a   Ramos Figueira, Estela Regina ^a   Bacchella, Telésforo ^a   Costa, Silvia Figueiredo ^a   Carneiro D'Albuquerque, Luiz Augusto ^a   Abdala, Edson ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC THERAPY; ARTICLE; COLD ISCHEMIA; CYTOMEGALOVIRUS INFECTION; END STAGE LIVER DISEASE; FEMALE; GRAFT RECIPIENT; HUMAN; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MYCOSIS; OUTCOME ASSESSMENT; OVERALL SURVIVAL; POST TREATMENT SURVIVAL; PRIORITY JOURNAL; REOPERATION; RETRANSPLANTATION; RISK FACTOR; SCORING SYSTEM; SURGICAL INFECTION; TREATMENT DURATION;

BACTERIAL INFECTIONS; BLOOD TRANSFUSION; END STAGE LIVER DISEASE; FEMALE; HUMANS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PROPORTIONAL HAZARDS MODELS; REGRESSION ANALYSIS; REOPERATION; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SURGICAL WOUND INFECTION; TIME FACTORS; TREATMENT OUTCOME;

EID: 84883207744     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.23682     Document Type: Article

References (38)

1. Anderson DJ, Kaye KS, Classen D, Arias KM, Podgorny K, Burstin H, et al. Strategies to prevent surgical site infections in acute care hospitals. Infect Control Hosp Epidemiol 2008; 29 (suppl 1): S51-S61.
2. Dummer JS,. Infections in solid organ transplant recipients., In,:, Mandell GL, Bennett, JE, Dolin, R, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 6th ed. Philadelphia, PA: Churchill Livingstone; 2005: 3501-3512.
3. Hellinger WC, Crook JE, Heckman MG, Diehl NN, Shalev JA, Zubair AC, et al. Surgical site infection after liver transplantation: risk factors and association with graft loss or death. Transplantation 2009; 87: 1387-1393.
4. García Prado ME, Matia EC, Ciuro FP, Díez-Canedo JS, Sousa Martín JM, Porras Lõpez FM, et al. Surgical site infection in liver transplant recipients: impact of the type of perioperative prophylaxis. Transplantation 2008; 85: 1849-1854.
5. Hollenbeak CS, Alfrey EJ, Sheridan K, Burger TL, Dillon PW,. Surgical site infections following pediatric liver transplantation: risks and costs. Transpl Infect Dis 2003; 5: 72-78.
6. Hollenbeak CS, Alfrey EJ, Souba WW,. The effect of surgical site infections on outcomes and resource utilization after liver transplantation. Surgery 2001; 130: 388-395.
7. Hellinger WC, Heckman MG, Crook JE, Taner CB, Willingham DL, Diehl NN, et al. Association of surgeon with surgical site infection after liver transplantation. Am J Transplant 2011; 11: 1877-1884.
8. Park C, Hsu C, Neelakanta G, Nourmand H, Braunfeld M, Wray C, et al. Severe intraoperative hyperglycemia is independently associated with surgical site infection after liver transplantation. Transplantation 2009; 87: 1031-1036.
9. Asensio A, Ramos A, Cuervas-Mons V, Cordero E, Sánchez- Turriõn V, Blanes M, et al.; for Red de Estudio de la Infecciõn en el Trasplante-Grupo de Estudio de la Infecciõn en el Trasplante. Effect of antibiotic prophylaxis on the risk of surgical site infection in orthotopic liver transplant. Liver Transpl 2008; 14: 799-805.
10. Iinuma Y, Senda K, Fujihara N, Saito T, Takakura S, Kudo T, et al. Surgical site infection in living-donor liver transplant recipients: a prospective study. Transplantation 2004; 78: 704-709.
11. Bert F, Larroque B, Paugam-Burtz C, Janny S, Durand F, Dondero F, et al. Microbial epidemiology and outcome of bloodstream infections in liver transplant recipients: an analysis of 259 episodes. Liver Transpl 2010; 16: 393-401.
12. Singh N, Gayowski T, Wagener MM,. Posttransplantation dialysis-associated infections: morbidity and impact on outcome in liver transplant recipients. Liver Transpl 2001; 7: 100-105.
13. Sharma P, Schaubel DE, Guidinger MK, Goodrich NP, Ojo AO, Merion RM,. Impact of MELD-based allocation on end-stage renal disease after liver transplantation. Am J Transplant 2011; 11: 2372-2378.
14. Kanwal F, Dulai GS, Spiegel BM, Yee HF, Gralnek IM,. A comparison of liver transplantation outcomes in the pre- vs. post-MELD eras. Aliment Pharmacol Ther 2005; 21: 169-177.
15. Horan TC, Andrus M, Dudeck MA,. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008; 36: 309-332.
16. Ljungman P, Griffiths P, Paya C,. Definitions of cytomegalovirus infection and disease in transplant recipients. Clin Infect Dis 2002; 34: 1094-1097.
17. Sun HY, Cacciarelli TV, Singh N,. Identifying a targeted population at high risk for infections after liver transplantation in the MELD era. Clin Transplant 2011; 25: 420-425.
18. Raghuram A, Restrepo A, Safadjou S, Cooley J, Orloff M, Hardy D, et al. Invasive fungal infections following liver transplantation: incidence, risk factors, survival, and impact of fluconazole-resistant Candida parapsilosis (2003-2007). Liver Transpl 2012; 18: 1100-1109.
19. Husain S, Tollemar J, Dominguez EA, Baumgarten K, Humar A, Paterson DL, et al. Changes in the spectrum and risk factors for invasive candidiasis in liver transplant recipients: prospective, multicenter, case-controlled study. Transplantation 2003; 75: 2023-2029.
20. Pacholczyk M, Lagiewska B, Lisik W, Wasiak D, Chmura A,. Invasive fungal infections following liver transplantation-risk factors, incidence and outcome. Ann Transplant 2011; 16: 14-16.
21. Auzinger G,. Invasive candidiasis following liver transplantation and surgical complications. Mycoses 2011; 54 (suppl 4): 4-7.
22. Kim YJ, Yoon JH, Kim SI, Hong KW, Kim JI, Choi JY, et al. High mortality associated with Acinetobacter species infection in liver transplant patients. Transplant Proc 2011; 43: 2397-2399.
23. Mrzljak A, Peric Z, Kovacevic V, Gustin D, Vrhovac R, Andrasevic AT,. Rising problem of multidrug-resistant gram-negative bacteria causing bloodstream infections after liver transplantation: how should we handle the issue? Liver Transpl 2010; 16: 1217-1219.
24. Shi SH, Kong HS, Xu J, Zhang WJ, Jia CK, Wang WL, et al. Multidrug resistant gram-negative bacilli as predominant bacteremic pathogens in liver transplant recipients. Transpl Infect Dis 2009; 11: 405-412.
25. Patel G, Huprikar S, Factor SH, Jenkins SG, Calfee DP,. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 2008; 29: 1099-1106.
26. Bergamasco MD, Barroso Barbosa M, de Oliveira Garcia D, Cipullo R, Moreira JC, Baia C, et al. Infection with Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae in solid organ transplantation. Transpl Infect Dis 2012; 14: 198-205.
27. Cockbain AJ, Goldsmith PJ, Gouda M, Attia M, Pollard SG, Lodge JP, et al. The impact of postoperative infection on long-term outcomes in liver transplantation. Transplant Proc 2010; 42: 4181-4183.
28. Frongillo F, Grossi U, Avolio AW, Sganga G, Nure E, Pepe G, et al. Factors predicting ischemic-type biliary lesions (ITBLs) after liver transplantation. Transplant Proc 2012; 44: 2002-2004.
29. Martin EF, Huang J, Xiang Q, Klein JP, Bajaj J, Saeian K,. Recipient survival and graft survival are not diminished by simultaneous liver-kidney transplantation: an analysis of the United Network for Organ Sharing database. Liver Transpl 2012; 18: 914-929.
30. Dacha S, Barad A, Martin J, Levitsky J,. Association of hepatic artery stenosis and biliary strictures in liver transplant recipients. Liver Transpl 2011; 17: 849-854.
31. Xu ZD, Xu HT, Yuan HB, Zhang H, Ji RH, Zou Z, et al. Postreperfusion syndrome during orthotopic liver transplantation: a single-center experience. Hepatobiliary Pancreat Dis Int 2012; 11: 34-39.
32. Paugam-Burtz C, Kavafyan J, Merckx P, Dahmani S, Sommacale D, Ramsay M, et al. Postreperfusion syndrome during liver transplantation for cirrhosis outcome and predictors. Liver Transpl 2009; 15: 522-529.
33. Zhong L, Men TY, Li H, Peng ZH, Gu Y, Ding X, et al. Multidrug-resistant gram-negative bacterial infections after liver transplantation-spectrum and risk factors. J Infect 2012; 64: 299-310.
34. Papanicolaou GA, Meyers BR, Meyers J, Mendelson MH, Lou W, Emre S, et al. Nosocomial infections with vancomycin-resistant Enterococcus faecium in liver transplant recipients: risk factors for acquisition and mortality. Clin Infect Dis 1996; 23: 760-766.
35. Linares L, Sanclemente G, Cervera C, Hoyo I, Cofán F, Ricart MJ, et al. Influence of cytomegalovirus disease in outcome of solid organ transplant patients. Transplant Proc 2011; 43: 2145-2148.
36. Cervera C, Fernández-Ruiz M, Valledor A, Linares L, Antõn A, Ángeles Marcos M, et al. Epidemiology and risk factors for late infection in solid organ transplant recipients. Transpl Infect Dis 2011; 13: 598-607.
37. Lautenschlager I,. CMV infection, diagnosis and antiviral strategies after liver transplantation. Transpl Int 2009; 22: 1031-1040.
38. Razonable RR,. Cytomegalovirus infection after liver transplantation: current concepts and challenges. World J Gastroenterol 2008; 14: 4849-4860.