Surgical site infection after liver transplantation: Risk factors and association with graft loss or death

Transplantation

Volumn 87, Issue 9, 2009, Pages 1387-1393

  Hellinger, Walter C ^a   Crook, Julia E ^a   Heckman, Michael G ^a   Diehl, Nancy N ^a   Shalev, Jefree A ^a   Zubair, Abba C ^a   Willingham, Darrin L ^a   Hewitt, Winston R ^a   Grewal, Hani P ^a   Nguyen, Justin H ^a   Hughes, Christopher B ^a  

^a MAYO CLINIC   (United States)

Author keywords

Death; Graft survival; Liver transplantation; Surgical site infection

Indexed keywords

ADULT; ARTICLE; BODY MASS; COHORT ANALYSIS; CONFIDENCE INTERVAL; DISEASE ASSOCIATION; FEMALE; GRAFT FAILURE; GRAFT SURVIVAL; HOSPITAL INFECTION; HUMAN; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; OPERATION DURATION; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; STANDARDIZATION; SURGICAL INFECTION; UNITED STATES;

AGED; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; HUMANS; INFECTION; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; RISK FACTORS; SURGICAL WOUND INFECTION; TIME FACTORS; TREATMENT FAILURE;

EID: 67649619521     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3181a25133     Document Type: Article

References (29)

1. Emori TG, Gaynes RP. An overview of nosocomial infections, including the role of the microbiology laboratory. Clin Microbiol Rev 1993; 6: 428.
2. Martone WJ, Nichols RL. Recognition, prevention, surveillance, and management of surgical site infections: Introduction to the problem and symposium overview. Clin Infect Dis 2001; 33(suppl 2): S67.
3. Kirkland KB, Briggs JP, Trivette SL, et al. The impact of surgical-site infections in the 1990s: Attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 1999; 20: 725.
4. Martone WJ, Jarvis WR, Edwards JR, et al. Incidence and nature of endemic and epidemic nosocomial infections. In: Bennett JV, Brachman PS, eds. Hospital infections, [ed. 4]. Philadelphia, Lippincott-Raven 1998, p 461.
5. Mangram AJ, Horan TC, Pearson ML, et al., Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Guideline for prevention of surgical site infection, 1999. Am J Infect Control 1999; 27: 97.
6. Tang GH, Maganti M, Weisel RD, et al. Prevention and management of deep sternal wound infection. Semin Thorac Cardiovasc Surg 2004; 16: 62.
7. Larsen JW, Hager WD, Livengood CH, et al. Guidelines for the diagnosis, treatment and prevention of postoperative infections. Infect Dis Obstet Gynecol 2003; 11: 65.
8. Cruse PJ, Foord R. The epidemiology of wound infection: A 10-year prospective study of 62,939 wounds. Surg Clin North Am 1980; 60: 27.
9. Condon RE, Schulte WJ, Malangoni MA, et al. Effectiveness of a surgical wound surveillance program. Arch Surg 1983; 118: 303.
10. Haley RW, Culver DH, White JW, et al. The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals. Am J Epidemiol 1985; 121: 182.
11. The Society for Hospital Epidemiology of America, the Association for Practitioners in Infection Control, the Centers for Disease Control, the Surgical Infection Society. Consensus paper on the surveillance of surgical wound infections. Infect Control Hosp Epidemiol 1992; 13: 599.
12. Dummer JS. Infections in solid organ transplant recipients. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett's principles and practice of infectious diseases, vol. 2. [ed. 6]. Philadelphia, Elsevier 2005, p 3501.
13. Hollenbeak CS, Alfrey EJ, Souba WW. The effect of surgical site infections on outcomes and resource utilization after liver transplantation. Surgery 2001; 130: 388.
14. Paya CV, Wiesner RH, Hermans PE, et al. Risk factors for cytomegalovirus and severe bacterial infections following liver transplantation: A prospective multivariate time-dependent analysis. J Hepatol 1993; 18: 185 [Erratum in: J Hepatol 1993; 19: 325].
15. Narayanan Menon KV, Nyberg SL, Harmsen WS, et al. MELD and other factors associated with survival after liver transplantation. Am J Transplant 2004; 4: 819.
16. Matinlauri IH, Nurminen MM, Hockerstedt KA, et al. Risk factors predicting survival of liver transplantation. Transplant Proc 2005; 37: 1155.
17. Moore DE, Feurer ID, Speroff T, et al. Impact of donor, technical, and recipient risk factors on survival and quality of life after liver transplantation. Arch Surg 2005; 140: 273.
18. Rustgi VK, Marino G, Rustgi S, et al. Impact of body mass index on graft failure and overall survival following liver transplant. Clin Transplant2004; 18: 634.
19. Castellvi JM, Xiol X, Guardiola J, et al. Pretransplantation risk factors for graft loss after liver transplantation in cirrhotic patients: Effect of cytomegalovirus serologic status. Transpl Int 2004; 17: 131.
20. Tippner C, Nashan B, Hoshino K, et al. Clinical and subclinical acute rejection early after liver transplantation: Contributing factors and relevance for the long-term course. Transplantation 2001; 72: 1122.
21. Markmann JF, Markmann JW, Markmann DA, et al. Preoperative factors associated with outcome and their impact on resource use in 1148 consecutive primary liver transplants. Transplantation 2001; 72: 1113.
22. Sawyer RG, Pelletier SJ, Pruett TL. Increased early morbidity and mortality with acceptable long-term function in severely obese patients undergoing liver transplantation. Clin Transplant 1999; 13(1 Pt 2): 126.
23. Wade JJ, Rolando N, Hayllar K, et al. Bacterial and fungal infections after liver transplantation: An analysis of 284 patients. Hepatology 1995; 21: 1328.
24. George DL, Arnow PM, Fox AS, et al. Bacterial infection as a complication of liver transplantation: Epidemiology and risk factors. Rev Infect Dis 1991; 13: 387.
25. Iinuma Y, Senda K, Fujihara N, et al. Surgical site infection in livingdonor liver transplant recipients: A prospective study. Transplantation2004; 78: 704.
26. George MJ, Snydman DR, Werner BG, et al.; Boston Center for Liver Transplantation CMVIG-Study Group. The independent role of cytomegalovirus as a risk factor for invasive fungal disease in orthotopic liver transplant recipients. Am J Med 1997; 103: 106.
27. Culver DH, Horan TC, Gaynes RP, et al. Surgical wound infection rates by wound class, operative procedure, and patient risk index: National Nosocomial Infections Surveillance System. Am J Med 1991; 91(3B): 152S-157S.
28. Roy MC, Herwaldt LA, Embrey R, et al. Does the Centers for Disease Control's NNIS system risk index stratify patients undergoing cardiothoracic operations by their risk of surgical-site infection? Infect Control Hosp Epidemiol 2000; 21: 186.
29. Friedman ND, Bull AL, Russo PL, et al. An alternative scoring system to predict risk for surgical site infection complicating coronary artery bypass graft surgery. Infect Control Hosp Epidemiol 2007; 28: 1162.