Microbial epidemiology and outcome of bloodstream infections in liver transplant recipients: An analysis of 259 episodes

Liver Transplantation

Volumn 16, Issue 3, 2010, Pages 393-401

  Bert, Frédéric ^a   Larroque, Beatrice ^a   Paugam Burtz, Catherine ^a   Janny, Sylvie ^a   Durand, Francois ^a,b   Dondero, Fédérica ^b   Valla, Dominique Charles ^a,b   Belghiti, Jacques ^b   Moreau, Richard ^a,b   Nicolas Chanoine, Marie Hélene ^a  

^a CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

^b BEAUJON HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMPICILLIN; CEFEPIME; CEFOXITIN; CEFTAZIDIME; CIPROFLOXACIN; FLUCONAZOLE; GENTAMICIN; IMIPENEM; METICILLIN; PIPERACILLIN PLUS TAZOBACTAM; VANCOMYCIN;

ABDOMINAL INFECTION; ADULT; ANTIBIOTIC RESISTANCE; ARTICLE; BILIARY TRACT INFECTION; BLOODSTREAM INFECTION; CATHETER INFECTION; ENTEROBACTERIACEAE; ENTEROCOCCUS; FEMALE; GRAFT RECIPIENT; HUMAN; INCIDENCE; LIVER TRANSPLANTATION; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL COMMUNITY; MORTALITY; OUTCOME ASSESSMENT; PATHOGENESIS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; SURVIVAL RATE; URINARY TRACT INFECTION; WOUND INFECTION; YEAST;

ADULT; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MICROBIAL; ENTEROBACTERIACEAE INFECTIONS; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; INCIDENCE; KAPLAN-MEIERS ESTIMATE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PROGNOSIS; RETROSPECTIVE STUDIES; STAPHYLOCOCCAL INFECTIONS; STREPTOCOCCAL INFECTIONS; TREATMENT OUTCOME;

EID: 77749320146     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.21991     Document Type: Article

References (35)

1. Kusne S, Dummer JS, Singh N, Iwatsuki S, Makowka L, Esquivel C, et al. Infections after liver transplantation: an analysis of 101 consecutive cases. Medicine 1988;67: 132-143.
2. George DL, Arnow PM, Fox AS, Baker AL, Thistlethwaite JR, Emond JC, et al. Bacterial infection as a complication of liver transplantation: epidemiology and risk factors. Rev Infect Dis 1991;13:387-396.
3. Wagener MM, Yu VL. Bacteremia in transplant recipients: a prospective study of demographics, etiologic agents; risk factors, and outcomes. Am J Infect Control 1992;20:239-247.
4. Singh N, Gayowski T, Wagener MM, Marino IR. Bloodstream infections in liver transplant recipients receiving tacrolimus. Clin Transplant 1997;11:275-281.
5. Wade JJ, Rolando N, Hayllar K, Philpott-Howard J, Casewell MW, Williams R. Bacterial and fungal infections after liver transplantation: an analysis of 284 patients. Hepatology 1995;21:1328-1336.
6. Singh N, Paterson DL, Gayowski T, Wagener MM, Marino IR. Predicting bacteremia and bacteremic mortality in liver transplant recipients. Liver Transpl 2000;6:54-61.
7. Nieto-Rodriguez JA, Kusne S, Mañez R, Irish W, Linden P, Magnone M, et al. Factors associated with the development of candidemia and candidemia-related death among liver transplant recipients. Ann Surg 1996;223:70-76.
8. Husain S, Tollemar J, Dominguez EA, Baumgarten K, Humar A, Paterson DL, et al. Changes in the spectrum and risk factors for invasive candidiasis in liver transplant recipients: prospective, multicenter, case-controlled study. Transplantation 2003;75:2023-2029.
9. Bert F, Galdbart J-O, Zarrouk V, Le Mée J, Durand F, Mentré F, et al. Association between Staphylococcus aureus nasal carriage and infection in liver transplant recipients. Clin Infect Dis 2000;31:1295-1299.
10. Torres-Cisneros J, Herrero C, Cañas E, Reguera JM, de la Mata M, Gómez-Bravo MA. High mortality related with Staphylococcus aureus bacteremia after liver transplantation. Eur J Clin Microbiol Infect Dis 2002;21:385-388.
11. Singh N, Wagener MM, Obman A, Cacciarelli TV, de Vera ME, Gayowski T. Bacteremias in liver transplant recipients: shift toward gram-negative bacteria as predominant pathogens. Liver Transpl 2004;10:844-849.
12. Kawecki D, Chmura A, Pacholczyk M, Lagiewska B, Adadynski L, Wasiak D, et al. Etiological agents of bacteremia in the early period after liver transplantation. Transplant Proc 2007;39:2816-2821.
13. Moreno A, Cervera C, Gavaldá J, Rovira M, de la Camara R, Jarque I, et al. Bloodstream infections among transplant recipients: results of a nationwide surveillance in Spain. Am J Transplant 2007;7:2579-2586.
14. Saner FH, Olde Damink SWM, Pavlakovic G, van den Broek MAJ, Rath P-M, Sotiropoulos GC, et al. Pulmonary and bloodstream infections in adult living donor and cadaveric liver transplant patients. Transplantation 2008;85:1564-1568.
15. Kim SI, Kim YJ, Jun YH, Wie SH, Kim YR, Choi JY, et al. Epidemiology and risk factors for bacteremia in 144 consecutive living-donor liver transplant recipients. Yonsei Med J 2009;50:112-121.
16. Jarlier V, Nicolas M-H, Fournier G, Philippon A. Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev Infect Dis 1988;10:867-878.
17. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions of nosocomial infections. Am J Infect Control 1988;16:128-140.
18. Raad I, Hanna HA, Alakech B, Chatzinikolaou I, Johnson MM, Tarrand J. Differential time to positivity: a useful method for diagnosing catheter-related infections. Ann Intern Med 2004;140:18-25.
19. O'Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, et al. Guidelines for the prevention of intravascular catheter-related infections. Infect Control Hosp Epidemiol 2002;23:759-769.
20. Bedini A, Codeluppi M, Cocchi S, Guaraldi G, Di Benedetto F, Venturelli C, et al. Gram-positive bloodstream infections in liver transplant recipients: incidence, risk factors, and impact on survival. Transplant Proc 2007; 39:1947-1949.
21. Al-Hasan MN, Razonable RR, Eckel-Passow JE, Baddour LM. Incidence rate and outcome of gram-negative bloodstream infection in solid organ transplant recipients. Am J Transplant 2009;9:835-843.
22. Bert F, Bellier C, Lassel L, Lefranc V, Durand F, Belghiti J, et al. Risk factors for Staphylococcus aureus infection for liver transplant recipients. Liver Transpl 2005;11: 1093-1099.
23. Pungpapong S, Alvarez S, Hellinger WC, Kramer DJ, Willingham DL, Mendez JC, et al. Peritonitis after liver transplantation: incidence, risk factors, microbiologic profiles, and outcome. Liver Transpl 2006;12:1244-1252.
24. Bellier C, Bert F, Durand F, Retout S, Belghiti J, Mentré F, Fantin B. Risk factors for Enterobacteriaceae bacteremia after liver transplantation. Transpl Int 2008;21: 755-763.
25. Singh N, Squier C, Wannstedt C, Keyes L, Wagener MM, Cacciarelli TV. Impact of an aggressive infection control strategy on endemic Staphylococcus aureus infection in liver transplant recipients. Infect Control Hosp Epidemiol 2006;27:122-126.
26. Singh N, Gayowski T, Rihs JD, Wagener MM, Marino IR. Evolving trends in multiple-antibiotic-resistant bacteria in liver transplant recipients: a longitudinal study of antimicrobial susceptibility patterns. Liver Transpl 2001; 7:22-26.
27. ZhouJD, Guo JJ, ZhangQ, Chen Y, Zhu SH, Peng HY.Drug resistance of infectious pathogens after liver transplantation. Hepatobiliary Pancreat Dis Int 2006;5:190-194.
28. García Prado ME, Cordero Matia E, Pareja Ciuro F, Díez-Canedo JS, Sousa Martín JM, Porras López FM, et al. Surgical site infection in liver transplant recipients: impact of the type of perioperative prophylaxis. Transplantation 2008;85:1849-1854.
29. Shi SH, Kong HS, Xu J, Zhang WJ, Jia CK, Wang WL, et al. Multidrug resistant gram-negative bacilli as predominant bacteremic pathogens in liver transplant recipients. Transplant Infect Dis 2009;11:405-412.
30. Rodríguez-Baňo J, Navarro MD, Romero L, Muniain MA, de Cueto M, Ríos MJ, et al. Bacteremia due to extendedspectrum β-lactamase-producing Escherichia coli in the CTX-M era: a new clinical challenge. Clin Infect Dis 2006;43:1407.
31. Nicolas-Chanoine M-H, Blanco J, Leflon-Guibout V, Demarty R, Alonso MP, Caniça MM, et al. Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15. J Antimicrob Chemother 2008;61: 273-281.
32. Werner G, Coque TM, Hammerum AM, Hope R, Hryniewicz W, Johnson A, et al. Emergence and spread of vancomycin resistance among enterococci in Europe. Euro Surveill 2008;20:19046.
33. Danziger-Isakov LA, Sweet S, Delamorena M, Huddleston CB, Mendeloff E, Debaun MR. Epidemiology of bloodstream infections in the first year after pediatric lung transplantation. Pediatric Infect Dis J 2005;24:324-330.
34. Smith JO, Shiffman ML, Behnke M, Stravitz RT, Luketic VA, Sanyal AJ, et al. Incidence of prolonged length of stay after orthotopic liver transplantation and its influence on outcomes. Liver Transpl 2009;15:273-279.
35. Habib S, Berk B, Chang C-CH, Demetris AJ, Fontes P, Dvorchik I, et al. MELD and prediction of post-liver transplantation survival. Liver Transpl 2006;12:440-447.