Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 704-718

  Tiwari, Manindra Nath ^a   Agarwal, Swati ^a,c   Bhatnagar, Priyanka ^b   Singhal, Naveen Kumar ^a   Tiwari, Shashi Kant ^a,c   Kumar, Pradeep ^b   Chauhan, Lalit Kumar Singh ^a   Patel, Devendra Kumar ^a   Chaturvedi, Rajnish Kumar ^a,c   Singh, Mahendra Pratap ^a   Gupta, Kailash Chand ^a,b  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^c ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

Author keywords

1 Methyl 4 phenyl 1,2,3,6 tetrahydropyridine; Free radicals; Neuroprotection; Nicotine encapsulated; Parkinson disease; PLGA nanoparticles

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CASPASE 3; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; METALLOTHIONEIN III; NERVE CELL ADHESION MOLECULE; NEUROMODULIN; NEUROPROTECTIVE AGENT; NICOTINE; NITRITE; POLYGLACTIN; PROTEIN P53; TYROSINE 3 MONOOXYGENASE; LACTIC ACID; NANOCONJUGATE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CORPUS STRIATUM; DRUG BIOAVAILABILITY; DRUG EFFICACY; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; INTERNALIZATION; LIPID PEROXIDATION; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; SUBSTANTIA NIGRA; ANIMAL; BRAIN; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; NERVE CELL; PARKINSONISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

MUS; PARKINSONIA; RODENTIA;

ANIMALS; BLOTTING, WESTERN; BRAIN; CELL SURVIVAL; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; LACTIC ACID; MICE; NANOCONJUGATES; NEURONS; NEUROPROTECTIVE AGENTS; NICOTINE; OXIDATIVE STRESS; PARKINSONIAN DISORDERS; POLYGLYCOLIC ACID; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84883192944     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.07.042     Document Type: Article

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