Mycoplasma fermentans Inhibits the Activity of Cellular DNA Topoisomerase I by Activation of PARP1 and Alters the Efficacy of Its Anti-Cancer Inhibitor

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Afriat, Reuven ^a   Horowitz, Shulamith ^a   Priel, Esther ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; CAMPTOTHECIN DERIVATIVE; DNA TOPOISOMERASE; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR;

ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CANCER RESISTANCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; MYCOPLASMA FERMENTANS; MYCOPLASMOSIS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

BACTERIAL PROTEINS; BENZAMIDES; CAMPTOTHECIN; DNA; DNA TOPOISOMERASES, TYPE I; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; HOST-PATHOGEN INTERACTIONS; HUMANS; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MCF-7 CELLS; MYCOPLASMA FERMENTANS; MYCOPLASMA INFECTIONS; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN KINASE INHIBITORS; PROTEINS; TOPOISOMERASE I INHIBITORS;

EID: 84883188070     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072377     Document Type: Article

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