TWEAK promotes osteoclastogenesis in rheumatoid arthritis

American Journal of Pathology

Volumn 183, Issue 3, 2013, Pages 857-867

  Park, Jin Sil ^a   Kwok, Seung Ki ^a   Lim, Mi Ae ^a   Oh, Hye Joa ^a   Kim, Eun Kyung ^a   Jhun, Joo Yeon ^a   Ju, Ji Hyeon ^a   Park, Kyung Su ^a   Park, Young Woo ^b   Park, Sung Hwan ^a   Kim, Ho Youn ^a   Cho, Young Gyu ^c   Cho, Mi La ^a  

^a The Catholic University of Korea   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Handok Pharmaceuticals Co Ltd   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR INDUCIBLE 14; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN SERINE THREONINE KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR TWEAK; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE CELL; CELL ISOLATION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN TISSUE; JOINT; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SPLEEN CELL; STEM CELL; SYNOVIAL FLUID LEVEL; SYNOVIOCYTE; SYNOVIUM; UPREGULATION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; FIBROBLASTS; HUMANS; JOINTS; MACROPHAGE COLONY-STIMULATING FACTOR; MALE; MICE; OSTEOCLASTS; OSTEOGENESIS; RANK LIGAND; SPLEEN; SYNOVIAL FLUID; TUMOR NECROSIS FACTORS;

EID: 84883185923     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.05.027     Document Type: Article

References (30)

1. G.S. Firestein Invasive fibroblast-like synoviocytes in rheumatoid arthritis: passive responders or transformed aggressors? Arthritis Rheum 39 1996 1781 1790
2. M. Feldmann, F.M. Brennan, and R.N. Maini Rheumatoid arthritis Cell 85 1996 307 310
3. E.T. Molenaar, A.E. Voskuyl, H.J. Dinant, P.D. Bezemer, M. Boers, and B.A. Dijkmans Progression of radiologic damage in patients with rheumatoid arthritis in clinical remission Arthritis Rheum 50 2004 36 42
4. E.M. Gravallese Bone destruction in arthritis Ann Rheum Dis 61 Suppl 2 2002 ii84 ii86
5. D. O'Gradaigh, D. Ireland, S. Bord, and J.E. Compston Joint erosion in rheumatoid arthritis: interactions between tumour necrosis factor alpha, interleukin 1, and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclasts Ann Rheum Dis 63 2004 354 359
6. S.H. Lee, T.S. Kim, Y. Choi, and J. Lorenzo Osteoimmunology: cytokines and the skeletal system BMB Rep 41 2008 495 510
7. J. Lorenzo, M. Horowitz, and Y. Choi Osteoimmunology: interactions of the bone and immune system Endocr Rev 29 2008 403 440
8. Y. Chicheportiche, P.R. Bourdon, H. Xu, Y.M. Hsu, H. Scott, C. Hession, I. Garcia, and J.L. Browning TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis J Biol Chem 272 1997 32401 32410
9. C.N. Lynch, Y.C. Wang, J.K. Lund, Y.W. Chen, J.A. Leal, and S.R. Wiley TWEAK induces angiogenesis and proliferation of endothelial cells J Biol Chem 274 1999 8455 8459
10. S.R. Wiley, L. Cassiano, T. Lofton, T. Davis-Smith, J.A. Winkles, V. Lindner, H. Liu, T.O. Daniel, C.A. Smith, and W.C. Fanslow A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis Immunity 15 2001 837 846
11. S.R. Wiley, and J.A. Winkles TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor Cytokine Growth Factor Rev 14 2003 241 249
12. S. Campbell, J. Michaelson, L. Burkly, and C. Putterman The role of TWEAK/Fn14 in the pathogenesis of inflammation and systemic autoimmunity Front Biosci 9 2004 2273 2284
13. Y. Chicheportiche, R. Chicheportiche, I. Sizing, J. Thompson, C.B. Benjamin, C. Ambrose, and J.M. Dayer Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies Arthritis Res 4 2002 126 133
14. K. Kamata, S. Kamijo, A. Nakajima, A. Koyanagi, H. Kurosawa, H. Yagita, and K. Okumura Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis J Immunol 177 2006 6433 6439
15. S.J. Perper, B. Browning, L.C. Burkly, S. Weng, C. Gao, K. Giza, L. Su, L. Tarilonte, T. Crowell, L. Rajman, L. Runkel, M. Scott, G.J. Atkins, D.M. Findlay, T.S. Zheng, and H. Hess TWEAK is a novel arthritogenic mediator J Immunol 177 2006 2610 2620
16. S. Kamijo, A. Nakajima, K. Kamata, H. Kurosawa, H. Yagita, and K. Okumura Involvement of TWEAK/Fn14 interaction in the synovial inflammation of RA Rheumatology (Oxford) 47 2008 442 450
17. M.C. Park, S.J. Chung, Y.B. Park, and S.K. Lee Relationship of serum TWEAK level to cytokine level, disease activity, and response to anti-TNF treatment in patients with rheumatoid arthritis Scand J Rheumatol 37 2008 173 178
18. A.W. van Kuijk, C.A. Wijbrandts, M. Vinkenoog, T.S. Zheng, K.A. Reedquist, and P.P. Tak TWEAK and its receptor Fn14 in the synovium of patients with rheumatoid arthritis compared to psoriatic arthritis and its response to tumour necrosis factor blockade Ann Rheum Dis 69 2010 301 304
19. A.A. Dharmapatni, M.D. Smith, T.N. Crotti, C.A. Holding, C. Vincent, H.M. Weedon, A.C. Zannettino, T.S. Zheng, D.M. Findlay, G.J. Atkins, and D.R. Haynes TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis Arthritis Res Ther 13 2011 R51
20. Y.Y. Kong, U. Feige, I. Sarosi, B. Bolon, A. Tafuri, S. Morony, C. Capparelli, J. Li, R. Elliott, S. McCabe, T. Wong, G. Campagnuolo, E. Moran, E.R. Bogoch, G. Van, L.T. Nguyen, P.S. Ohashi, D.L. Lacey, E. Fish, W.J. Boyle, and J.M. Penninger Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand Nature 402 1999 304 309
21. J.H. Ju, M.L. Cho, Y.M. Moon, H.J. Oh, J.S. Park, J.Y. Jhun, S.Y. Min, Y.G. Cho, K.S. Park, C.H. Yoon, J.K. Min, S.H. Park, Y.C. Sung, and H.Y. Kim IL-23 induces receptor activator of NF-kappaB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model J Immunol 181 2008 1507 1518
22. F.C. Arnett, S.M. Edworthy, D.A. Bloch, D.J. McShane, J.F. Fries, N.S. Cooper, L.A. Healey, S.R. Kaplan, M.H. Liang, H.S. Luthra, T.A. Medsger, D.M. Mitchell, D.H. Neustadt, R.S. Pinals, J.G. Schaller, J.T. Sharp, R.L. Wilder, and G.G. Hunder The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 1988 315 324
23. M.L. Cho, W.U. Kim, S.Y. Min, D.J. Min, J.K. Min, S.H. Lee, S.H. Park, C.S. Cho, and H.Y. Kim Cyclosporine differentially regulates interleukin-10, interleukin-15, and tumor necrosis factor a production by rheumatoid synoviocytes Arthritis Rheum 46 2002 42 51
24. Y.Y. Kong, H. Yoshida, I. Sarosi, H.L. Tan, E. Timms, C. Capparelli, S. Morony, A.J. Oliveira-dos-Santos, G. Van, A. Itie, W. Khoo, A. Wakeham, C.R. Dunstan, D.L. Lacey, T.W. Mak, W.J. Boyle, and J.M. Penninger OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis Nature 397 1999 315 323
25. H. Takayanagi, H. Iizuka, T. Juji, T. Nakagawa, A. Yamamoto, T. Miyazaki, Y. Koshihara, H. Oda, K. Nakamura, and S. Tanaka Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis Arthritis Rheum 43 2000 259 269
26. K.W. Kim, M.L. Cho, S.H. Lee, H.J. Oh, C.M. Kang, J.H. Ju, S.Y. Min, Y.G. Cho, S.H. Park, and H.Y. Kim Human rheumatoid synovial fibroblasts promote osteoclastogenic activity by activating RANKL via TLR-2 and TLR-4 activation Immunol Lett 110 2007 54 64
27. H.M. Hulsmans, J.W. Jacobs, D.M. van der Heijde, G.A. van Albada-Kuipers, Y. Schenk, and J.W. Bijlsma The course of radiologic damage during the first six years of rheumatoid arthritis Arthritis Rheum 43 2000 1927 1940
28. E. Lindqvist, K. Jonsson, T. Saxne, and K. Eberhardt Course of radiographic damage over 10 years in a cohort with early rheumatoid arthritis Ann Rheum Dis 62 2003 611 616
29. E. Lindqvist, T. Saxne, P. Geborek, and K. Eberhardt Ten year outcome in a cohort of patients with early rheumatoid arthritis: health status, disease process, and damage Ann Rheumatic Dis 61 2002 1055 1059
30. T.C. Polek, M. Talpaz, B.G. Darnay, and T. Spivak-Kroizman TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR: evidence for a second TWEAK receptor J Biol Chem 278 2003 32317 32323