The multiplicity of human formins: Expression patterns in cells and tissues

Cytoskeleton

Volumn 70, Issue 8, 2013, Pages 424-438

  Krainer, Elisabeth C ^a   Ouderkirk, Jessica L ^a   Miller, Eric W ^a   Miller, Matthew R ^a   Mersich, Akos T ^a   Blystone, Scott D ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Actin; tissues; PCR; expression; Formins

Indexed keywords

ACTIN BINDING PROTEIN; DELPHILIN; DIAPHANOUS FORMIN 1; DIAPHANOUS FORMIN 2; DIAPHANOUS FORMIN 3; DISHEVELED ASSOCIATED ACTIVATORS OF MORPHOGENESIS 1 PROTEIN; DISHEVELED ASSOCIATED ACTIVATORS OF MORPHOGENESIS 2 PROTEIN; FORMIN HOMOLOGY DOMAIN CONTAINING PROTEIN 1; FORMIN HOMOLOGY DOMAIN CONTAINING PROTEIN 3; FORMIN RELATED PROTEIN IDENTIFIED IN LEUKOCYTE 1; FORMIN RELATED PROTEIN IDENTIFIED IN LEUKOCYTE 2; FORMIN RELATED PROTEIN IDENTIFIED IN LEUKOCYTE 3; INVERTED FORMIN 1; INVERTED FORMIN 2; ORIGINAL FORMIN 1; ORIGINAL FORMIN 2; PROTEIN FORMIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL STRAIN HEK293; CELL TYPE; EPITHELIUM CELL; HELA CELL; HEMATOPOIETIC CELL; HUMAN; HUMAN TISSUE; LEUKEMIA CELL LINE; MACROPHAGE; MESENCHYME CELL; MONOCYTE; MUSCLE CELL; NERVE CELL; NEUTROPHIL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SYSTEMATIC REVIEW; THROMBOCYTE; TISSUE DISTRIBUTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ACTIN; TISSUES; PCR; EXPRESSION; FORMINS;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CYTOSKELETAL PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEINS;

EID: 84883169922     PISSN: 19493584     EISSN: 19493592     Source Type: Journal    
DOI: 10.1002/cm.21113     Document Type: Article

References (45)

1. Aspenstrom P. 2010. Formin-binding proteins: modulators of formin-dependent actin polymerization. Biochim Biophys Acta 1803:2174-2182.
2. Block J, Breitsprecher D, Kuhn S. 2012. FMNL2 drives actin-based protrusion and migration downstream of Cdc42. Curr Biol 22:111005-111012.
3. Blystone SD, Williams MP, Slater SE, Brown EJ. 1997. Requirement of integrin beta3 tyrosine 747 for beta3 tyrosine phosphorylation and regulation of alphavbeta3 avidity. J Biol Chem 272:4528757-4528761.
4. Bustin SA. 2002. Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. J Mol Endocrinol 29:123-139.
5. Bustin SA, Benes V, Garson JA. 2009. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55:4611-4622.
6. Campellone KG, Welch MD. 2010. A nucleator arms race: cellular control of actin assembly. Nat Rev Mol Cell Biol 11:4237-4251.
7. Castrillon DH, Wasserman SA. 1994. Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development 120:123367-123377.
8. Chae SC, Inazu Y, Amagai A, Maeda Y. 1998. Underexpression of a novel gene, dia2, impairs the transition of Dictyostelium cells from growth to differentiation. Biochem Biophys Res Commun 252:1278-1283.
9. Chesarone MA, DuPage AG, Goode BL. 2010. Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol 11:162-174.
10. Chhabra ES, Higgs HN. 2006. INF2 Is a WASP homology 2 motif-containing formin that severs actin filaments and accelerates both polymerization and depolymerization. J Biol Chem 281:3626754-3626767.
11. Chhabra ES, Higgs HN. 2007. The many faces of actin: matching assembly factors with cellular structures. Nat Cell Biol 9:101110-101121.
12. Colon-Franco JM, Gomez TS, Billadeau DD. 2011. Dynamic remodeling of the actin cytoskeleton by FMNL1gamma is required for structural maintenance of the Golgi complex. J Cell Sci 124:183118-183126.
13. Copeland JW, Copeland SJ, Treisman R. 2004. Homo-oligomerization is essential for F-actin assembly by the formin family FH2 domain. J Biol Chem 279:4850250-4850256.
14. Evangelista M, Zigmond S, Boone C. 2003. Formins: signaling effectors for assembly and polarization of actin filaments. J Cell Sci 116:132603-132611.
15. Goode BL, Eck MJ. 2007. Mechanism and function of formins in the control of actin assembly. Annu Rev Biochem 76:593-627.
16. Habas R, Kato Y, He X. 2001. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 107:7843-7854.
17. Harris ES, Gauvin TJ, Heimsath EG, Higgs HN. 2010. Assembly of filopodia by the formin FRL2 (FMNL3). Cytoskeleton (Hoboken) 67:12755-12772.
18. Higgs HN, Peterson KJ. 2005. Phylogenetic analysis of the formin homology 2 domain. Mol Biol Cell 16:11-13.
19. Jones SL, Wang J, Turck CW, Brown EJ. 1998. A role for the actin-bundling protein L-plastin in the regulation of leukocyte integrin function. Proc Natl Acad Sci USA 95:169331-169336.
20. Katoh M, Katoh M. 2003a. Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico. Int J Oncol 22:51161-51168.
21. Katoh M, Katoh M. 2003b. Identification and characterization of human DAAM2 gene in silico. Int J Oncol 22:4915-4920.
22. Katoh M, Katoh M. 2003c. Identification and characterization of human GRID2IP gene and rat Grid2ip gene in silico. Int J Mol Med 12:61015-61019.
23. Katoh M, Katoh M. 2004a. Identification and characterization of human FHDC1, mouse Fhdc1 and zebrafish fhdc1 genes in silico. Int J Mol Med 13:6929-6934.
24. Katoh M, Katoh M. 2004b. Identification and characterization of the human FMN1 gene in silico. Int J Mol Med 14:1121-1126.
25. Katoh M, Katoh M. 2004c. Characterization of FMN2 gene at human chromosome 1q43. Int J Mol Med 14:3469-3474.
26. Kida Y, Shiraishi T, Ogura T. 2004. Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system. Brain Res Dev Brain Res 153:1143-1150.
27. Kovar DR. 2006. Molecular details of formin-mediated actin assembly. Curr Opin Cell Biol 18:111-117.
28. Lee HK, Deneen B. 2012. Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord. Dev Cell 22:1183-1196.
29. Li F, Higgs HN. 2003. The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition. Curr Biol 13:151335-151340.
30. Matsuda K, Matsuda S, Gladding CM, Yuzaki M. 2006. Characterization of the delta2 glutamate receptor-binding protein delphilin: splicing variants with differential palmitoylation and an additional PDZ domain. J Biol Chem 281:3525577-3525587.
31. Mersich AT, Miller MR, Chkourko H, Blystone SD. 2010. The formin FRL1 (FMNL1) is an essential component of macrophage podosomes. Cytoskeleton (Hoboken) 67:9573-9585.
32. Miyagi Y, Yamashita T, Fukaya M. 2002. Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit. J Neurosci 22:3803-3814.
33. Nolan T, Hands RE, Bustin SA. 2006. Quantification of mRNA using real-time RT-PCR. Nat Protoc 1:31559-31582.
34. Paul AS, Pollard TD. 2008. The role of the FH1 domain and profilin in formin-mediated actin-filament elongation and nucleation. Curr Biol 18:9-19.
35. Paul AS, Pollard TD. 2009. Energetic requirements for processive elongation of actin filaments by FH1FH2-formins. J Biol Chem 284:1812533-1812540.
36. Peng J, Wallar BJ, Flanders A, Swiatek PJ, Alberts AS. 2003. Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42. Curr Biol 13:7534-7545.
37. Schonichen A, Geyer M. 2010. Fifteen formins for an actin filament: a molecular view on the regulation of human formins. Biochim Biophys Acta 1803:2152-2163.
38. Schroeder A, Mueller O, Stocker S, Salowsky R, Leiber M, Gassmann M, Lightfoot S, Menzel W, Granzow M, Ragg T. 2006. The RIN: an RNA integrity number for assigning integrity values to RNA measurements. BMC Mol Biol 7:3.
39. Ståhlberg A, Hakansson J, Xian X, Semb H, Kubista M. 2004. Properties of the reverse transcription reaction in mRNA quantification. Clin Chem 50:3509-3515.
40. Taniguchi K, Takeya R, Suetsugu S, Kan-O M, Narusawa M, Shiose A, Tominaga R, Sumimoto H 2009. Mammalian formin fhod3 regulates actin assembly and sarcomere organization in striated muscles. J Biol Chem 284:4329873-4329881.
41. Tanizaki H, Egawa G, Inaba K. 2010. Rho-mDia1 pathway is required for adhesion, migration, and T-cell stimulation in dendritic cells. Blood 116:265875-265884.
42. Wallar BJ, Alberts AS. 2003. The formins: active scaffolds that remodel the cytoskeleton. Trends Cell Biol 13:8435-8446.
43. Watanabe-Kaneko K, Sonoda T, Miyagi Y, Yamashita T, Okuda K, Kawamoto S. 2007. The synaptic scaffolding protein Delphilin interacts with monocarboxylate transporter 2. Neuroreport 18:5489-5493.
44. Westendorf JJ, Mernaugh R, Hiebert SW. 1999. Identification and characterization of a protein containing formin homology (FH1/FH2) domains. Gene 232:2173-2182.
45. Zigmond SH, Evangelista M, Boone C, Yang C, Dar AC, Sicheri F, Forkey J, Pring M. 2003. Formin leaky cap allows elongation in the presence of tight capping proteins. Curr Biol 13:201820-201823.