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Volumn 13, Issue 7, 2013, Pages 755-765

Functional dysconnectivity in schizophrenia and its relationship to neural synchrony

Author keywords

synchrony; Biological mechanism; Circuits; Cognition; Functional connectivity; Genes; Neurons; Neurotransmitters; Schizophrenia

Indexed keywords

BUNGAROTOXIN RECEPTOR; CIGARETTE SMOKE; DOPAMINE; GLUTAMATE DECARBOXYLASE 67; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID;

EID: 84883154561     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/14737175.2013.811899     Document Type: Review
Times cited : (20)

References (95)
  • 1
    • 22144432283 scopus 로고    scopus 로고
    • A systematic review of the prevalence of schizophrenia
    • Saha S, Chant D, Welham J, McGrath J. A systematic review of the prevalence of schizophrenia. PLoS Med. 2(5), e141 (2005).
    • (2005) PLoS Med. , vol.2 , Issue.5
    • Saha, S.1    Chant, D.2    Welham, J.3    McGrath, J.4
  • 2
    • 84868261937 scopus 로고    scopus 로고
    • Global burden of disease
    • WHO. Geneva, Switzerlan
    • WHO. Global Burden of Disease. WHO, Geneva, Switzerland (2004).
    • (2004) WHO
  • 3
    • 0029918481 scopus 로고    scopus 로고
    • What are the functional consequences of neurocognitive deficits in schizophrenia
    • Green MF. What are the functional consequences of neurocognitive deficits in schizophrenia? Am. J. Psychiatry 153(3), 321-330 (1996).
    • (1996) Am. J. Psychiatr , vol.153 , Issue.3 , pp. 321-330
    • Green, M.F.1
  • 4
    • 78149428430 scopus 로고    scopus 로고
    • Rethinking schizophrenia
    • Insel TR. Rethinking schizophrenia. Nature 468(7321), 187-193 (2010).
    • (2010) Natur , vol.468 , Issue.7321 , pp. 187-193
    • Insel, T.R.1
  • 5
    • 21644447473 scopus 로고    scopus 로고
    • No authors listed. So much more to know
    • No authors listed. So much more to know. Science 309(5731), 78-102 (2005).
    • (2005) Science , vol.309 , Issue.5731 , pp. 78-102
  • 6
    • 84869025817 scopus 로고    scopus 로고
    • Using summary data from the Danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder
    • Wray NR, Gottesman II. Using summary data from the Danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder. Front. Genet. 3, 118 (2012).
    • (2012) Front. Genet , vol.3 , Issue.118
    • Wray, N.R.1    Gottesman, I.I.2
  • 7
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: Evidence from a meta-analysis of twin studies
    • Sullivan PF, Kendler KS, Neale MC. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch. Gen. Psychiatry 60(12), 1187-1192 (2003).
    • (2003) Arch. Gen. Psychiatr , vol.60 , Issue.12 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 8
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 160(4), 636-645 (2003).
    • (2003) Am. J. Psychiatr , vol.160 , Issue.4 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 10
    • 84865430154 scopus 로고    scopus 로고
    • People living with psychotic illness 2010: Report on the
    • Commonwealth of Australia, Canberra, Australi
    • Morgan VA, Waterreus A, Jablensky A et al. People Living with Psychotic Illness 2010: Report on the Second Australian National Survey. Commonwealth of Australia, Canberra, Australia (2011).
    • (2011) Second Australian National Survey
    • Morgan, V.A.1    Waterreus, A.2    Jablensky, A.3
  • 12
    • 7544244277 scopus 로고    scopus 로고
    • Longitudinal studies of cognition and functional outcome in schizophrenia: Implications for MATRICS
    • Green MF, Kern RS, Heaton RK. Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS. Schizophr. Res. 72(1), 41-51 (2004).
    • (2004) Schizophr. Res. , vol.72 , Issue.1 , pp. 41-51
    • Green, M.F.1    Kern, R.S.2    Heaton, R.K.3
  • 13
    • 33748924655 scopus 로고    scopus 로고
    • Intermediate phenotypes and genetic mechanisms of psychiatric disorders
    • Meyer-Lindenberg A, Weinberger DR. Intermediate phenotypes and genetic mechanisms of psychiatric disorders. Nat. Rev. Neurosci. 7(10), 818-827 (2006).
    • (2006) Nat. Rev. Neurosci , vol.7 , Issue.10 , pp. 818-827
    • Meyer-Lindenberg, A.1    Weinberger, D.R.2
  • 14
    • 0031835226 scopus 로고    scopus 로고
    • From sensation to cognition
    • Mesulam MM. From sensation to cognition. Brain 121(Pt 6), 1013-1052 (1998).
    • (1998) Brain , vol.121 , Issue.PART 6 , pp. 1013-1052
    • Mesulam, M.M.1
  • 17
    • 0015422512 scopus 로고
    • Prospects for research on schizophrenia. 3. Neurophysiology. Neuropathological findings
    • Plum F. Prospects for research on schizophrenia. 3. Neurophysiology. Neuropathological findings. Neurosci. Res. Program Bull. 10(4), 384-388 (1972).
    • (1972) Neurosci. Res. Program Bull. , vol.10 , Issue.4 , pp. 384-388
    • Plum, F.1
  • 18
    • 0022616146 scopus 로고
    • Benes FM, Davidson J, Bird ED. Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics
    • Benes FM, Davidson J, Bird ED. Quantitative cytoarchitectural studies of the cerebral cortex of schizophrenics. Arch. Gen. Psychiatry 43(1), 31-35 (1986).
    • (1986) Arch. Gen. Psychiatr , vol.43 , Issue.1 , pp. 31-35
  • 19
    • 0029198619 scopus 로고
    • Schizophrenia: A disconnection syndrome
    • Friston KJ, Frith CD. Schizophrenia: a disconnection syndrome? Clin. Neurosci. 3(2), 89-97 (1995).
    • (1995) Clin. Neurosci , vol.3 , Issue.2 , pp. 89-97
    • Friston, K.J.1    Frith, C.D.2
  • 20
    • 0031750915 scopus 로고    scopus 로고
    • Cognitive dysmetria' as an integrative theory of schizophrenia: A dysfunction in cortical-subcortical-cerebellar circuitry
    • Andreasen NC, Paradiso S, O'Leary DS.'Cognitive dysmetria' as an integrative theory of schizophrenia: a dysfunction in cortical-subcortical- cerebellar circuitry? Schizophr. Bull. 24(2), 203-218 (1998).
    • (1998) Schizophr. Bull. , vol.24 , Issue.2 , pp. 203-218
    • Andreasen, N.C.1    Paradiso, S.2    O'Leary D.S.'3
  • 22
    • 65349122415 scopus 로고    scopus 로고
    • Dysconnection in schizophrenia: From abnormal synaptic plasticity to failures of self-monitoring
    • Stephan KE, Friston KJ, Frith CD. Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring. Schizophr. Bull. 35(3), 509-527 (2009).
    • (2009) Schizophr. Bull. , vol.35 , Issue.3 , pp. 509-527
    • Stephan, K.E.1    Friston, K.J.2    Frith, C.D.3
  • 23
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • image 5
    • Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol. Psychiatry 10(1), 40-68; image 5 (2005).
    • (2005) Mol. Psychiatr , vol.10 , Issue.1 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 24
    • 33845804083 scopus 로고    scopus 로고
    • Neuroimaging of schizophrenia: Structural abnormalities and pathophysiological implications
    • Buckley PF. Neuroimaging of schizophrenia: structural abnormalities and pathophysiological implications. Neuropsychiatr. Dis. Treat. 1(3), 193-204 (2005).
    • (2005) Neuropsychiatr. Dis. Treat , vol.1 , Issue.3 , pp. 193-204
    • Buckley, P.F.1
  • 25
    • 0024255761 scopus 로고
    • Coherent oscillations: A mechanism of feature linking in the visual cortex? Multiple electrode and correlation analyses in the cat
    • Eckhorn R, Bauer R, Jordan W et al. Coherent oscillations: a mechanism of feature linking in the visual cortex? Multiple electrode and correlation analyses in the cat. Biol. Cybern. 60(2), 121-130 (1988).
    • (1988) Biol. Cybern , vol.60 , Issue.2 , pp. 121-130
    • Eckhorn, R.1    Bauer, R.2    Jordan, W.3
  • 26
    • 0033521914 scopus 로고    scopus 로고
    • Perception's shadow: Long-distance synchronization of human brain activity
    • Rodriguez E, George N, Lachaux JP, Martinerie J, Renault B, Varela FJ. Perception's shadow: long-distance synchronization of human brain activity. Nature 397(6718), 430-433 (1999).
    • (1999) Natur , vol.397 , Issue.6718 , pp. 430-433
    • Rodriguez, E.1    George, N.2    Lachaux, J.P.3    Martinerie, J.4    Renault, B.5    Varela, F.J.6
  • 27
    • 0033521910 scopus 로고    scopus 로고
    • Coherence of β-band EEG activity as a basis for associative learning
    • Miltner WH, Braun C, Arnold M, Witte H, Taub E. Coherence of β-band EEG activity as a basis for associative learning. Nature 397(6718), 434-436 (1999).
    • (1999) Natur , vol.397 , Issue.6718 , pp. 434-436
    • Miltner, W.H.1    Braun, C.2    Arnold, M.3    Witte, H.4    Taub, E.5
  • 28
    • 66349096611 scopus 로고    scopus 로고
    • High-frequency, long-range coupling between prefrontal and visual cortex during attention
    • Gregoriou GG, Gotts SJ, Zhou H, Desimone R. High-frequency, long-range coupling between prefrontal and visual cortex during attention. Science 324(5931), 1207-1210 (2009).
    • (2009) Scienc , vol.324 , Issue.5931 , pp. 1207-1210
    • Gregoriou, G.G.1    Gotts, S.J.2    Zhou, H.3    Desimone, R.4
  • 29
    • 13844265736 scopus 로고    scopus 로고
    • Functional coupling between frontal and parietal lobes during recognition memory
    • Summerfield C, Mangels JA. Functional coupling between frontal and parietal lobes during recognition memory. Neuroreport 16(2), 117-122 (2005).
    • (2005) Neurorepor , vol.16 , Issue.2 , pp. 117-122
    • Summerfield, C.1    Mangels, J.A.2
  • 31
    • 75649088570 scopus 로고    scopus 로고
    • Abnormal neural oscillations and synchrony in schizophrenia
    • Uhlhaas PJ, Singer W. Abnormal neural oscillations and synchrony in schizophrenia. Nat. Rev. Neurosci. 11(2), 100-113 (2010).
    • (2010) Nat. Rev. Neurosci , vol.11 , Issue.2 , pp. 100-113
    • Uhlhaas, P.J.1    Singer, W.2
  • 32
    • 0029147220 scopus 로고
    • Temporal structure in spatially organized neuronal ensembles: A role for interneuronal networks
    • Buzsáki G, Chrobak JJ. Temporal structure in spatially organized neuronal ensembles: a role for interneuronal networks. Curr. Opin. Neurobiol. 5(4), 504-510 (1995).
    • (1995) Curr. Opin. Neurobiol , vol.5 , Issue.4 , pp. 504-510
    • Buzsáki, G.1    Chrobak, J.J.2
  • 34
    • 33845794324 scopus 로고    scopus 로고
    • Synaptic mechanisms of synchronized γ oscillations in inhibitory interneuron networks
    • Bartos M, Vida I, Jonas P. Synaptic mechanisms of synchronized γ oscillations in inhibitory interneuron networks. Nat. Rev. Neurosci. 8(1), 45-56 (2007).
    • (2007) Nat. Rev. Neurosci , vol.8 , Issue.1 , pp. 45-56
    • Bartos, M.1    Vida, I.2    Jonas, P.3
  • 35
    • 7544237332 scopus 로고    scopus 로고
    • Measurement and treatment research to improve cognition in schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia
    • Marder SR, Fenton W. Measurement and treatment research to improve cognition in schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia. Schizophr. Res. 72(1), 5-9 (2004).
    • (2004) Schizophr. Res. , vol.72 , Issue.1 , pp. 5-9
    • Marder, S.R.1    Fenton, W.2
  • 37
    • 43949122546 scopus 로고    scopus 로고
    • Premorbid IQ in schizophrenia: A metaanalytic review
    • Woodberry KA, Giuliano AJ, Seidman LJ. Premorbid IQ in schizophrenia: a metaanalytic review. Am. J. Psychiatry 165(5), 579-587 (2008).
    • (2008) Am. J. Psychiatr , vol.165 , Issue.5 , pp. 579-587
    • Woodberry, K.A.1    Giuliano, A.J.2    Seidman, L.J.3
  • 39
    • 13444271819 scopus 로고    scopus 로고
    • Neurocognitive impairment across the lifespan in schizophrenia: An update
    • Kurtz MM. Neurocognitive impairment across the lifespan in schizophrenia: an update. Schizophr. Res. 74(1), 15-26 (2005).
    • (2005) Schizophr. Res. , vol.74 , Issue.1 , pp. 15-26
    • Kurtz, M.M.1
  • 41
    • 53249152777 scopus 로고    scopus 로고
    • The role of oscillations and synchrony in cortical networks and their putative relevance for the pathophysiology of schizophrenia
    • Uhlhaas PJ, Haenschel C, Nikolic D, Singer W. The role of oscillations and synchrony in cortical networks and their putative relevance for the pathophysiology of schizophrenia. Schizophr. Bull. 34(5), 927-943 (2008).
    • (2008) Schizophr. Bull. , vol.34 , Issue.5 , pp. 927-943
    • Uhlhaas, P.J.1    Haenschel, C.2    Nikolic, D.3    Singer, W.4
  • 42
    • 0037219228 scopus 로고    scopus 로고
    • Synchronous γ activity: A review and contribution to an integrative neuroscience model of schizophrenia
    • Lee KH, Williams LM, Breakspear M, Gordon E. Synchronous γ activity: a review and contribution to an integrative neuroscience model of schizophrenia. Brain Res. Brain Res. Rev. 41(1), 57-78 (2003).
    • (2003) Brain Res. Brain Res. Rev. , vol.41 , Issue.1 , pp. 57-78
    • Lee, K.H.1    Williams, L.M.2    Breakspear, M.3    Gordon, E.4
  • 43
    • 54149109208 scopus 로고    scopus 로고
    • GABA neurons and the mechanisms of network oscillations: Implications for understanding cortical dysfunction in schizophrenia
    • Gonzalez-Burgos G, Lewis DA. GABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophrenia. Schizophr. Bull. 34(5), 944-961 (2008).
    • (2008) Schizophr. Bull. , vol.34 , Issue.5 , pp. 944-961
    • Gonzalez-Burgos, G.1    Lewis, D.A.2
  • 44
    • 33748208302 scopus 로고    scopus 로고
    • Dysfunctional long-range coordination of neural activity during Gestalt perception in schizophrenia
    • Uhlhaas PJ, Linden DE, Singer W et al. Dysfunctional long-range coordination of neural activity during Gestalt perception in schizophrenia. J. Neurosci. 26(31), 8168-8175 (2006).
    • (2006) J. Neurosci , vol.26 , Issue.31 , pp. 8168-8175
    • Uhlhaas, P.J.1    Linden, D.E.2    Singer, W.3
  • 46
    • 79251648566 scopus 로고    scopus 로고
    • Long-range synchrony of g oscillations and auditory hallucination symptoms in schizophrenia
    • Mulert C, Kirsch V, Pascual-Marqui R, McCarley RW, Spencer KM. Long-range synchrony of g oscillations and auditory hallucination symptoms in schizophrenia. Int. J. Psychophysiol. 79(1), 55-63 (2011).
    • (2011) Int. J. Psychophysiol , vol.79 , Issue.1 , pp. 55-63
    • Mulert, C.1    Kirsch, V.2    Pascual-Marqui, R.3    McCarley, R.W.4    Spencer, K.M.5
  • 47
    • 78249252030 scopus 로고    scopus 로고
    • Aberrant EEG responses to γ-frequency visual stimulation in schizophrenia
    • Riecanský I, Kašpá;rek T, Rehulová J, Katina S, Prikryl R. Aberrant EEG responses to γ-frequency visual stimulation in schizophrenia. Schizophr. Res. 124(1-3), 101-109 (2010).
    • (2010) Schizophr. Res. , vol.124 , Issue.1-3 , pp. 101-109
    • Riecanský, I.1    Kašpárek, T.2    Rehulová, J.3    Katina, S.4    Prikryl, R.5
  • 48
    • 53149090138 scopus 로고    scopus 로고
    • Increased absolute magnitude of γ synchrony in first-episode psychosis
    • Flynn G, Alexander D, Harris A et al. Increased absolute magnitude of γ synchrony in first-episode psychosis. Schizophr. Res. 105(1-3), 262-271 (2008).
    • (2008) Schizophr. Res. , vol.105 , Issue.1-3 , pp. 262-271
    • Flynn, G.1    Alexander, D.2    Harris, A.3
  • 49
    • 70149089716 scopus 로고    scopus 로고
    • Emotion-elicited γ synchrony in patients with first-episode schizophrenia: A neural correlate of social cognition outcomes
    • Williams LM, Whitford TJ, Nagy M et al. Emotion-elicited γ synchrony in patients with first-episode schizophrenia: a neural correlate of social cognition outcomes. J. Psychiatry Neurosci. 34(4), 303-313 (2009).
    • (2009) J. Psychiatry Neurosci , vol.34 , Issue.4 , pp. 303-313
    • Williams, L.M.1    Whitford, T.J.2    Nagy, M.3
  • 50
    • 14844292718 scopus 로고    scopus 로고
    • Gamma Synchrony in first-episode schizophrenia: A disorder of temporal connectivity
    • Symond MB, Harris AWF, Gordon E, Williams LM.'Gamma Synchrony' in first-episode schizophrenia: a disorder of temporal connectivity? Am. J. Psychiatry. 162(3), 459-465 (2005).
    • (2005) Am. J. Psychiatry , vol.162 , Issue.3 , pp. 459-465
    • Symond, M.B.1    Awf, H.2    Gordon, E.3    Williams, L.M.4
  • 52
    • 33845945707 scopus 로고    scopus 로고
    • Impairments in frontal cortical γ synchrony and cognitive control in schizophrenia
    • Cho RY, Konecky RO, Carter CS. Impairments in frontal cortical γ synchrony and cognitive control in schizophrenia. Proc. Natl Acad. Sci. USA 103(52), 19878-19883 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.52 , pp. 19878-19883
    • Cho, R.Y.1    Konecky, R.O.2    Carter, C.S.3
  • 54
    • 84865305316 scopus 로고    scopus 로고
    • Schizophrenia, neuroimaging and connectomics
    • Fornito A, Zalesky A, Pantelis C, Bullmore ET. Schizophrenia, neuroimaging and connectomics. Neuroimage 62(4), 2296-2314 (2012).
    • (2012) Neuroimag , vol.62 , Issue.4 , pp. 2296-2314
    • Fornito, A.1    Zalesky, A.2    Pantelis, C.3    Bullmore, E.T.4
  • 55
    • 77957367135 scopus 로고    scopus 로고
    • Impaired efficiency of functional networks underlying episodic memory-for-context in schizophrenia
    • Wang L, Metzak PD, Honer WG, Woodward TS. Impaired efficiency of functional networks underlying episodic memory-for-context in schizophrenia. J. Neurosci. 30(39), 13171-13179 (2010).
    • (2010) J. Neurosci , vol.30 , Issue.39 , pp. 13171-13179
    • Wang, L.1    Metzak, P.D.2    Honer, W.G.3    Woodward, T.S.4
  • 56
    • 78649639241 scopus 로고    scopus 로고
    • Error processing network dynamics in schizophrenia
    • Becerril KE, Repovs G, Barch DM. Error processing network dynamics in schizophrenia. Neuroimage 54(2), 1495-1505 (2011).
    • (2011) Neuroimag , vol.54 , Issue.2 , pp. 1495-1505
    • Becerril, K.E.1    Repovs, G.2    Barch, D.M.3
  • 57
    • 79958780727 scopus 로고    scopus 로고
    • General and specific functional connectivity disturbances in first-episode schizophrenia during cognitive control performance
    • Fornito A, Yoon J, Zalesky A, Bullmore ET, Carter CS. General and specific functional connectivity disturbances in first-episode schizophrenia during cognitive control performance. Biol. Psychiatry 70(1), 64-72 (2011).
    • (2011) Biol. Psychiatr , vol.70 , Issue.1 , pp. 64-72
    • Fornito, A.1    Yoon, J.2    Zalesky, A.3    Bullmore, E.T.4    Carter, C.S.5
  • 58
    • 84864228590 scopus 로고    scopus 로고
    • A framework for interpreting functional networks in schizophrenia
    • Williamson PC, Allman JM. A framework for interpreting functional networks in schizophrenia. Front. Hum. Neurosci. 6, 184 (2012).
    • (2012) Front. Hum. Neurosci , vol.6 , Issue.184
    • Williamson, P.C.1    Allman, J.M.2
  • 59
    • 74249089991 scopus 로고    scopus 로고
    • Neuronal correlates of functional magnetic resonance imaging in human temporal cortex
    • Ojemann GA, Corina DP, Corrigan N et al. Neuronal correlates of functional magnetic resonance imaging in human temporal cortex. Brain 133(Pt 1), 46-59 (2010).
    • (2010) Brain , vol.133 , Issue.46-59 PART 1
    • Ojemann, G.A.1    Corina, D.P.2    Corrigan, N.3
  • 61
    • 65349120160 scopus 로고    scopus 로고
    • The dopamine hypothesis of schizophrenia: Version III - The final common pathway
    • Howes OD, Kapur S. The dopamine hypothesis of schizophrenia: version III - the final common pathway. Schizophr. Bull. 35(3), 549-562 (2009).
    • (2009) Schizophr. Bull. , vol.35 , Issue.3 , pp. 549-562
    • Howes, O.D.1    Kapur, S.2
  • 62
    • 84864008358 scopus 로고    scopus 로고
    • Dopamine and γ band synchrony in schizophrenia - Insights from computational and empirical studies
    • Kömek K, Bard Ermentrout G, Walker CP, Cho RY. Dopamine and γ band synchrony in schizophrenia - insights from computational and empirical studies. Eur. J. Neurosci. 36(2), 2146-2155 (2012).
    • (2012) Eur. J. Neurosci , vol.36 , Issue.2 , pp. 2146-2155
    • Kömek, K.1    Bard Ermentrout, G.2    Walker, C.P.3    Cho, R.Y.4
  • 63
    • 84856120944 scopus 로고    scopus 로고
    • From revolution to evolution: The glutamate hypothesis of schizophrenia and its implication for treatment
    • Moghaddam B, Javitt D. From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatment. Neuropsychopharmacology 37(1), 4-15 (2012).
    • (2012) Neuropsychopharmacolog , vol.37 , Issue.1 , pp. 4-15
    • Moghaddam, B.1    Javitt, D.2
  • 64
    • 0037977113 scopus 로고    scopus 로고
    • Decreased serum levels of d-serine in patients with schizophrenia: Evidence in support of the N-methyl-d-aspartate receptor hypofunction hypothesis of schizophrenia
    • Hashimoto K, Fukushima T, Shimizu E et al. Decreased serum levels of d-serine in patients with schizophrenia: evidence in support of the N-methyl-d-aspartate receptor hypofunction hypothesis of schizophrenia. Arch. Gen. Psychiatry 60(6), 572-576 (2003).
    • (2003) Arch. Gen. Psychiatr , vol.60 , Issue.6 , pp. 572-576
    • Hashimoto, K.1    Fukushima, T.2    Shimizu, E.3
  • 66
    • 73949136265 scopus 로고    scopus 로고
    • Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes
    • Belforte JE, Zsiros V, Sklar ER et al. Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nat. Neurosci. 13(1), 76-83 (2010).
    • (2010) Nat. Neurosci , vol.13 , Issue.1 , pp. 76-83
    • Belforte, J.E.1    Zsiros, V.2    Sklar, E.R.3
  • 67
    • 84888307727 scopus 로고    scopus 로고
    • Molecular evidence of N-methyl-d-aspartate receptor hypofunction in schizophrenia
    • doi:10.1038/mp.2012.137 Epub ahead of print
    • Weickert CS, Fung SJ, Catts VS et al. Molecular evidence of N-methyl-d-aspartate receptor hypofunction in schizophrenia. Mol. Psychiatry doi:10.1038/mp.2012.137 (2012) (Epub ahead of print).
    • (2012) Mol. Psychiatr
    • Weickert, C.S.1    Fung, S.J.2    Catts, V.S.3
  • 68
    • 84857053838 scopus 로고    scopus 로고
    • Glutamatergic transmission in schizophrenia: From basic research to clinical practice
    • Kantrowitz J, Javitt DC. Glutamatergic transmission in schizophrenia: from basic research to clinical practice. Curr. Opin. Psychiatry 25(2), 96-102 (2012).
    • (2012) Curr. Opin. Psychiatr , vol.25 , Issue.2 , pp. 96-102
    • Kantrowitz, J.1    Javitt, D.C.2
  • 69
    • 77955048810 scopus 로고    scopus 로고
    • Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists
    • Krystal JH, Mathew SJ, D'Souza DC, Garakani A, Gunduz-Bruce H, Charney DS. Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists. CNS Drugs 24(8), 669-693 (2010).
    • (2010) CNS Drugs , vol.24 , Issue.8 , pp. 669-693
    • Krystal, J.H.1    Mathew, S.J.2    D'Souza, D.C.3    Garakani, A.4    Gunduz-Bruce, H.5    Charney, D.S.6
  • 70
    • 84874511848 scopus 로고    scopus 로고
    • Clinical trials of potential cognitive-enhancing drugs in schizophrenia: What have we learned so far?
    • Keefe RS, Buchanan RW, Marder SR et al. Clinical trials of potential cognitive-enhancing drugs in schizophrenia: what have we learned so far? Schizophr. Bull. 39(2), 417-435 (2013).
    • (2013) Schizophr. Bull. , vol.39 , Issue.2 , pp. 417-435
    • Keefe, R.S.1    Buchanan, R.W.2    Marder, S.R.3
  • 71
    • 80053583200 scopus 로고    scopus 로고
    • Genetics and function of neocortical GABAergic interneurons in neurodevelopmental disorders
    • Rossignol E. Genetics and function of neocortical GABAergic interneurons in neurodevelopmental disorders. Neural Plast. 2011, 649325 (2011).
    • (2011) Neural Plast , vol.2011 , pp. 649325
    • Rossignol, E.1
  • 72
    • 84867081926 scopus 로고    scopus 로고
    • Higher γ-aminobutyric acid neuron density in the white matter of orbital frontal cortex in schizophrenia
    • Joshi D, Fung SJ, Rothwell A, Weickert CS. Higher γ-aminobutyric acid neuron density in the white matter of orbital frontal cortex in schizophrenia. Biol. Psychiatry 72(9), 725-733 (2012).
    • (2012) Biol. Psychiatr , vol.72 , Issue.9 , pp. 725-733
    • Joshi, D.1    Fung, S.J.2    Rothwell, A.3    Weickert, C.S.4
  • 73
    • 42749095376 scopus 로고    scopus 로고
    • Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
    • Lisman JE, Coyle JT, Green RW et al. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 31(5), 234-242 (2008).
    • (2008) Trends Neurosci , vol.31 , Issue.5 , pp. 234-242
    • Lisman, J.E.1    Coyle, J.T.2    Green, R.W.3
  • 74
    • 84860502642 scopus 로고    scopus 로고
    • The role of glutamatergic inputs onto parvalbumin-positive interneurons: Relevance for schizophrenia
    • Rotaru DC, Lewis DA, Gonzalez-Burgos G. The role of glutamatergic inputs onto parvalbumin-positive interneurons: relevance for schizophrenia. Rev. Neurosci. 23(1), 97-109 (2012).
    • (2012) Rev. Neurosci , vol.23 , Issue.1 , pp. 97-109
    • Rotaru, D.C.1    Lewis, D.A.2    Gonzalez-Burgos, G.3
  • 75
    • 80051782825 scopus 로고    scopus 로고
    • Selective pyramidal cell reduction of GABA(A) receptor a1 subunit messenger RNA expression in schizophrenia
    • Glausier JR, Lewis DA. Selective pyramidal cell reduction of GABA(A) receptor a1 subunit messenger RNA expression in schizophrenia. Neuropsychopharmacology 36(10), 2103-2110 (2011).
    • (2011) Neuropsychopharmacolog , vol.36 , Issue.10 , pp. 2103-2110
    • Glausier, J.R.1    Lewis, D.A.2
  • 76
    • 83055171565 scopus 로고    scopus 로고
    • Downregulation of parvalbumin at cortical GABA synapses reduces network γ oscillatory activity
    • Volman V, Behrens MM, Sejnowski TJ. Downregulation of parvalbumin at cortical GABA synapses reduces network γ oscillatory activity. J. Neurosci. 31(49), 18137-18148 (2011).
    • (2011) J. Neurosci , vol.31 , Issue.49 , pp. 18137-18148
    • Volman, V.1    Behrens, M.M.2    Sejnowski, T.J.3
  • 77
    • 84855527488 scopus 로고    scopus 로고
    • Glutamate, obsessive-compulsive disorder, schizophrenia, and the stability of cortical attractor neuronal networks
    • Rolls ET. Glutamate, obsessive-compulsive disorder, schizophrenia, and the stability of cortical attractor neuronal networks. Pharmacol. Biochem. Behav. 100(4), 736-751 (2012).
    • (2012) Pharmacol. Biochem. Behav , vol.100 , Issue.4 , pp. 736-751
    • Rolls, E.T.1
  • 78
    • 84874511171 scopus 로고    scopus 로고
    • Early-life insults impair parvalbumin interneurons via oxidative stress: Reversal by N-acetylcysteine
    • Cabungcal JH, Steullet P, Kraftsik R, Cuenod M, Do KQ. Early-life insults impair parvalbumin interneurons via oxidative stress: reversal by N-acetylcysteine. Biol. Psychiatry 73(6), 574-582 (2013).
    • (2013) Biol. Psychiatr , vol.73 , Issue.6 , pp. 574-582
    • Cabungcal, J.H.1    Steullet, P.2    Kraftsik, R.3    Cuenod, M.4    Do, K.Q.5
  • 79
    • 84857482073 scopus 로고    scopus 로고
    • Glutathione precursor N-acetylcysteine modulates EEG synchronization in schizophrenia patients: A double-blind, randomized, placebo-controlled trial
    • Carmeli C, Knyazeva MG, Cuénod M, Do KQ. Glutathione precursor N-acetylcysteine modulates EEG synchronization in schizophrenia patients: a double-blind, randomized, placebo-controlled trial. PLoS ONE 7(2), e29341 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.2
    • Carmeli, C.1    Knyazeva, M.G.2    Cuénod, M.3    Do, K.Q.4
  • 80
    • 84857053370 scopus 로고    scopus 로고
    • The role of the a7 nicotinic receptor in cognitive processing of persons with schizophrenia
    • Ahn Allen CG. The role of the a7 nicotinic receptor in cognitive processing of persons with schizophrenia. Curr. Opin. Psychiatry 25(2), 103-108 (2012).
    • (2012) Curr. Opin. Psychiatr , vol.25 , Issue.2 , pp. 103-108
    • Ahn Allen, C.G.1
  • 81
    • 84856102195 scopus 로고    scopus 로고
    • GABAergic interneuron origin of schizophrenia pathophysiology
    • Nakazawa K, Zsiros V, Jiang Z et al. GABAergic interneuron origin of schizophrenia pathophysiology. Neuropharmacology 62(3), 1574-1583 (2012).
    • (2012) Neuropharmacolog , vol.62 , Issue.3 , pp. 1574-1583
    • Nakazawa, K.1    Zsiros, V.2    Jiang, Z.3
  • 82
    • 0028969330 scopus 로고
    • Visual feature integration and the temporal correlation hypothesis
    • Singer W, Gray CM. Visual feature integration and the temporal correlation hypothesis. Annu. Rev. Neurosci. 18, 555-586 (1995).
    • (1995) Annu. Rev. Neurosci , vol.18 , pp. 555-586
    • Singer, W.1    Gray, C.M.2
  • 83
    • 33846642542 scopus 로고    scopus 로고
    • The genetics of schizophrenia
    • Sullivan PF. The genetics of schizophrenia. PLoS Med. 2(7), e212 (2005).
    • (2005) PLoS Med. , vol.2 , Issue.7
    • Sullivan, P.F.1
  • 84
    • 80053384370 scopus 로고    scopus 로고
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Genome-wide association study identifies five new schizophrenia loci. Nat. Genet. 43(10), 969-976 (2011).
    • (2011) Nat. Genet , vol.43 , Issue.10 , pp. 969-976
  • 85
    • 77956647781 scopus 로고    scopus 로고
    • The neuregulin signaling pathway and schizophrenia: From genes to synapses and neural circuits
    • Buonanno A. The neuregulin signaling pathway and schizophrenia: from genes to synapses and neural circuits. Brain Res. Bull. 83(3-4), 122-131 (2010).
    • (2010) Brain Res. Bull. , vol.83 , Issue.3-4 , pp. 122-131
    • Buonanno, A.1
  • 86
    • 68449090594 scopus 로고    scopus 로고
    • Genetic Risk and Outcome in Psychosis (GROUP). Common variants conferring risk of schizophrenia
    • Stefansson H, Ophoff RA, Steinberg S et al.; Genetic Risk and Outcome in Psychosis (GROUP). Common variants conferring risk of schizophrenia. Nature 460(7256), 744-747 (2009).
    • (2009) Natur , vol.460 , Issue.7256 , pp. 744-747
    • Stefansson, H.1    Ophoff, R.A.2    Steinberg, S.3
  • 87
    • 84866736529 scopus 로고    scopus 로고
    • International Schizophrenia Consortium. Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia
    • Lips ES, Cornelisse LN, Toonen RF et al.; International Schizophrenia Consortium. Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia. Mol. Psychiatry 17(10), 996-1006 (2012).
    • (2012) Mol. Psychiatr , vol.17 , Issue.10 , pp. 996-1006
    • Lips, E.S.1    Cornelisse, L.N.2    Toonen, R.F.3
  • 88
    • 84866778453 scopus 로고    scopus 로고
    • The effects of psychosis risk variants on brain connectivity: A review
    • Mothersill O, Kelly S, Rose EJ, Donohoe G. The effects of psychosis risk variants on brain connectivity: a review. Front. Psychiatry 3, 18 (2012).
    • (2012) Front. Psychiatr , vol.3 , Issue.18
    • Mothersill, O.1    Kelly, S.2    Rose, E.J.3    Donohoe, G.4
  • 89
    • 78650770457 scopus 로고    scopus 로고
    • International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: Rationale and protocol
    • Williams LM, Rush AJ, Koslow SH et al. International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: rationale and protocol. Trials 12, 4 (2011).
    • (2011) Trial , vol.12 , Issue.4
    • Williams, L.M.1    Rush, A.J.2    Koslow, S.H.3
  • 90
    • 77954230363 scopus 로고    scopus 로고
    • Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders
    • Insel T, Cuthbert B, Garvey M et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am. J. Psychiatry 167(7), 748-751 (2010).
    • (2010) Am. J. Psychiatr , vol.167 , Issue.7 , pp. 748-751
    • Insel, T.1    Cuthbert, B.2    Garvey, M.3
  • 91
    • 16344378783 scopus 로고    scopus 로고
    • A six-factor model of cognition in schizophrenia and related psychotic disorders: Relationships with clinical symptoms and functional capacity
    • Gladsjo JA, McAdams LA, Palmer BW, Moore DJ, Jeste DV, Heaton RK. A six-factor model of cognition in schizophrenia and related psychotic disorders: relationships with clinical symptoms and functional capacity. Schizophr. Bull. 30(4), 739-754 (2004).
    • (2004) Schizophr. Bull. , vol.30 , Issue.4 , pp. 739-754
    • Gladsjo, J.A.1    McAdams, L.A.2    Palmer, B.W.3    Moore, D.J.4    Jeste, D.V.5    Heaton, R.K.6
  • 92
    • 34248174285 scopus 로고    scopus 로고
    • Overlooking the obvious: A meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophrenia
    • Dickinson D, Ramsey ME, Gold JM. Overlooking the obvious: a meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophrenia. Arch. Gen. Psychiatry 64(5), 532-542 (2007).
    • (2007) Arch. Gen. Psychiatr , vol.64 , Issue.5 , pp. 532-542
    • Dickinson, D.1    Ramsey, M.E.2    Gold, J.M.3
  • 93
    • 0031903740 scopus 로고    scopus 로고
    • Neurocognitive deficit in schizophrenia: A quantitative review of the evidence
    • Heinrichs RW, Zakzanis KK. Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology 12(3), 426-445 (1998).
    • (1998) Neuropsycholog , vol.12 , Issue.3 , pp. 426-445
    • Heinrichs, R.W.1    Zakzanis, K.K.2
  • 95
    • 0003322588 scopus 로고
    • Dementia praecox oder die Gruppe der Schizophrenien
    • Aschaffenburg, G (Ed.) Leipzig, Deuticke, German
    • Bleuler E. Dementia praecox oder die Gruppe der Schizophrenien. In:Hrsg. Handbuch der Psychiatrie . Aschaffenburg, G (Ed.) Leipzig, Deuticke, Germany (1911).
    • (1911) Hrsg. Handbuch der Psychiatri
    • Bleuler, E.1


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