Antibodies bound to Aβ oligomers potentiate the neurotoxicity of Aβ by activating microglia

Journal of Neurochemistry

Volumn 126, Issue 5, 2013, Pages 604-615

  Morkuniene, Ramune ^a   Zvirbliene, Aurelija ^b   Dalgediene, Indre ^b   Cizas, Paulius ^a   Jankeviciute, Silvija ^a   Baliutyte, Giedre ^a   Jokubka, Ramunas ^a   Jankunec, Marija ^b   Valincius, Gintaras ^b   Borutaite, Vilmante ^a  

^a LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

^b VILNIUS UNIVERSITY   (Lithuania)

Author keywords

Alzheimer's disease; antibodies; beta amyloid; neurons; neurotoxicity; oligomers

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CAPSID PROTEIN; IMMUNOGLOBULIN G1 ANTIBODY; NUCLEOCAPSID PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY COMPLEX; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG POTENTIATION; FEMALE; IN VITRO STUDY; INFLAMMATION; MALE; MEASLES VIRUS; METAPNEUMOVIRUS; MICROGLIA; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; POLYOMA VIRUS; PRIORITY JOURNAL; RAT;

ALZHEIMER'S DISEASE; ANTIBODIES; BETA AMYLOID; NEURONS; NEUROTOXICITY; OLIGOMERS;

AMYLOID BETA-PEPTIDES; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; MACROPHAGE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MICROGLIA; NEURONS; NEUROTOXICITY SYNDROMES; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

HAMSTER POLYOMAVIRUS; HUMAN METAPNEUMOVIRUS; MEASLES VIRUS; MIRIDAE;

EID: 84883136015     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12332     Document Type: Article

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