The independent, unfavorable prognostic factors endothelin A receptor and chemokine receptor 4 have a close relationship in promoting the motility of nasopharyngeal carcinoma cells via the activation of AKT and MAPK pathways

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Luo, Dong Hua ^a   Chen, Qiu Yan ^a   Liu, Huai ^a   Xu, Li Hua ^a,b   Zhang, Hui Zhong ^a   Zhang, Lu ^a   Tang, Lin Quan ^a   Mo, Hao Yuan ^a   Huang, Pei Yu ^a   Guo, Xiang ^a   Mai, Hai Qiang ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

CXCR4; ETAR; Metastasis; Nasopharyngeal carcinoma; Prognosis

Indexed keywords

ANTINEOPLASTIC AGENT; CHEMOKINE RECEPTOR CXCR4; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; STROMAL CELL DERIVED FACTOR 1ALPHA;

ADULT; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; CARCINOMA CELL; CELL MIGRATION; CELL MOTILITY; CELL STRAIN; CELL STRAIN 5 8F; CELL STRAIN 6 10B; CONTROLLED STUDY; CXCR4 GENE; DISTANT METASTASIS FREE SURVIVAL; ENZYME ACTIVATION; ETAR GENE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; NASOPHARYNX CARCINOMA; OVERALL SURVIVAL; PREDICTIVE VALUE; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CXCL12; CHEMOTAXIS; ENDOTHELIN-1; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; MULTIVARIATE ANALYSIS; NASOPHARYNGEAL NEOPLASMS; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, ENDOTHELIN A; RECEPTORS, CXCR4; RNA, MESSENGER; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84883097732     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-203     Document Type: Article

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