Study on pharmacokinetics of asperosaponin VI and its active metabolite in rats

Zhongguo Zhongyao Zazhi

Volumn 38, Issue 14, 2013, Pages 2378-2383

  Liu, Rui Juan ^a   Zhu, He ^a   Ding, Li ^a   Shakya, Shailendra ^a   Yang, Zhong Lin ^a   Cheng, Lu ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Asperosaponin VI; Biliary excretion; Equilibrium dialysis method; Hederagenin; Pharmacokinetics; Protein binding rate; Urinary excretion

Indexed keywords

ASPEROSAPONIN VI; DRUG METABOLITE; HEDERAGENIN; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BILIARY EXCRETION; DRUG ACCUMULATION; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG EXCRETION; DRUG FECES LEVEL; DRUG MEGADOSE; DRUG URINE LEVEL; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LOW DRUG DOSE; MASS SPECTROMETRY; NONHUMAN; PHARMACOKINETICS; PLASMA CONCENTRATION-TIME CURVE; PLASMA PROTEIN BINDING; RAT; URINARY EXCRETION;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BILE; DRUGS, CHINESE HERBAL; FEMALE; MALE; PLANTS, MEDICINAL; PROTEIN BINDING; RATS; SAPONINS;

EID: 84883041046     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20131433     Document Type: Article

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