Determination of asperosaponin VI in dog plasma by high-performance liquid chromatography-tandem mass spectrometry and its application to a pilot pharmacokinetic study

Biomedical Chromatography

Volumn 26, Issue 1, 2012, Pages 109-114

  Shakya, Shailendra ^a   Zhu, He ^a   Ding, Li ^a   Du, Xiao Lang ^a   Qi, Xie Min ^a   Yang, Xiao Lin ^a   Yang, Zhong Lin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Asperosaponin VI; Dog plasma; LC MS MS; Pharmacokinetics

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHANOL; NEGATIVE IONS;

ASPEROSAPONIN VI; BEAGLE DOG; DOG PLASMA; GLYCYRRHIZIC ACID; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; INTERNAL STANDARDS; ITS APPLICATIONS; LC-MS-MS; LC.MS/MS; PHARMACOKINETIC STUDIES;

PHARMACOKINETICS;

ACETIC ACID; AMMONIUM ACETATE; ANTIINFLAMMATORY AGENT; ASPEROSAPONIN 6; BUFFER; GLYCYRRHIZIC ACID; METHANOL; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIPSACACEAE; DOG; ELUTION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; NONHUMAN; PILOT STUDY; STANDARD; TANDEM MASS SPECTROMETRY;

EID: 83455243260     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1634     Document Type: Article

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