Update on allele nomenclature for human cytochromes P450 and the human cytochrome P450 allele (CYP-allele) nomenclature database

Methods in Molecular Biology

Volumn 987, Issue , 2013, Pages 251-259

  Sim, Sarah C ^a   Ingelman Sundberg, Magnus ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adverse drug reactions; Cytochrome P450; Drug response; NADPH cytochrome P450 reductase; Pharmacogenetics

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; CYTOCHROME P450 REDUCTASE; NUCLEOTIDE;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; DATA BASE; DRUG METABOLISM; DRUG RESPONSE; GENE SEQUENCE; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; NOMENCLATURE; PRIORITY JOURNAL; PROTEIN PROCESSING; PUBLICATION; GENETIC DATABASE; GENETICS; INTERNET;

ALLELES; CYTOCHROME P-450 ENZYME SYSTEM; DATABASES, GENETIC; HUMANS; INTERNET; TERMINOLOGY AS TOPIC;

EID: 84882989719     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-321-3_21     Document Type: Article

References (14)

1. Sim SC, Ingelman-Sundberg M (2011) Pharmacogenomic biomarkers: new tools in current and future drug therapy. Trends Pharmacol Sci 32:72-81
2. Paugh SW, Stocco G, McCorkle JR, Diouf B, Crews KR, Evans WE (2011) Cancer pharmacogenomics. Clin Pharmacol Ther 90:461-466
3. Ma Q, Lu AY (2011) Pharmacogenetics, pharmacogenomics, and individualized medicine. Pharmacol Rev 63:437-459
4. Wang L, McLeod HL, Weinshilboum RM (2011) Genomics and drug response. N Engl J Med 364:1144-1153
5. Ingelman-Sundberg M, Sim SC, Gomez A, Rodriguez-Antona C (2007) In fluence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacol Ther 116:496-526
6. Rodriguez-Antona C, Gomez A, Karlgren M, Sim SC, Ingelman-Sundberg M (2010) Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment. Hum Genet 127:1-17
7. Sim SC, Risinger C, Dahl ML, Aklillu E, Christensen M, Bertilsson L, Ingelman-Sundberg M (2006) A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther 79:103-113
8. Bertz RJ, Granneman GR (1997) Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet 32:210-258
9. Evans WE, Relling MV (1999) Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286:487-491
10. Sim SC, Altman RB, Ingelman-Sundberg M (2011) Databases in the area of pharmacogenetics. Hum Mutat 32:526-531
11. Ingelman-Sundberg M, Daly AK, Oscarson M, Nebert DW (2000) Human cytochrome P450 (CYP) genes: recommendations for the nomenclature of alleles. Pharmacogenetics 10:91-93
12. Sim SC, Ingelman-Sundberg M (2010) The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects. Hum Genomics 4:278-281
13. Oscarson M, Ingelman-Sundberg M (2002) CYPalleles: a web page for nomenclature of human cytochrome P450 alleles. Drug Metab Pharmacokinet 17:491-495
14. Sim SC, Miller WL, Zhong XB, Arlt W, Ogata T, Ding X, Wolf CR, Fluck CE, Pandey AV, Henderson CJ, Porter TD, Daly AK, Nebert DW, Ingelman-Sundberg M (2009) Nomenclature for alleles of the cytochrome P450 oxidoreductase gene. Pharmacogenet Genomics 19:565-566