Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with polycystic ovary syndrome: A meta-analysis

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 14, Issue 3, 2013, Pages 255-261

  Jia, Hongxia ^a   Wang, Bin ^b   Yu, Lili ^a   Jiang, Zhaoshun ^a  

^a JINAN MILITARY GENERAL HOSPITAL   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Angiotensin converting enzyme; association; meta analysis; polycystic ovary syndrome; polymorphism

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ARTICLE; ASIAN; CAUCASIAN; ETHNIC GROUP; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC POLYMORPHISM; GENETIC RISK; HIGH RISK POPULATION; HUMAN; INDEL MUTATION; META ANALYSIS (TOPIC); OVARY POLYCYSTIC DISEASE;

ANGIOTENSIN-CONVERTING ENZYME; ASSOCIATION; META-ANALYSIS; POLYCYSTIC OVARY SYNDROME; POLYMORPHISM;

FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDEL MUTATION; PEPTIDYL-DIPEPTIDASE A; POLYCYSTIC OVARY SYNDROME; POLYMORPHISM, GENETIC; PUBLICATION BIAS; RISK FACTORS;

EID: 84882960868     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320312452768     Document Type: Article

References (36)

1. Brassard M, AinMelk Y, Baillargeon JP. Basic infertility including polycystic ovary syndrome. Med Clin North Am. 2008 ; 92: 1163 xi - 1192
2. Goodarzi MO, Azziz R. Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome. Best Pract Res Clin Endocrinol Metab. 2006 ; 20: 193-205
3. Prapas N, Karkanaki A, Prapas I, et al. Genetics of polycystic ovary syndrome. Hippokratia. 2009 ; 13: 216-223
4. Yoshimura Y. The ovarian renin-angiotensin system in reproductive physiology. Front Neuroendocrinol. 1997 ; 18: 247-291
5. Ganong WF. Blood, pituitary, and brain renin-angiotensin systems and regulation of secretion of anterior pituitary gland. Front Neuroendocrinol. 1993 ; 14: 233-249
6. Steele MK, Gallo RV, Ganong WF. A possible role for the brain renin-angiotensin system in the regulation of LH secretion. Am J Physiol. 1983 ; 245: R805 - R810
7. Palumbo A, Jones C, Lightman A, et al. Immunohistochemical localization of renin and angiotensin II in human ovaries. Am J Obstet Gynecol. 1989 ; 160: 8-14
8. Hefler LA, Gregg AR. Influence of the angiotensinogen gene on the ovulatory capacity of mice. Fertil Steril. 2001 ; 75: 1206-1211
9. Palumbo A, Pourmotabbed G, Carcangiu ML, et al. Immunohistochemical localization of renin and angiotensin in the ovary: comparison between normal women and patients with histologically proven polycystic ovarian disease. Fertil Steril. 1993 ; 60: 280-284
10. Morris RS, Wong IL, Hatch IE, et al. Prorenin is elevated in polycystic ovary syndrome and may reflect hyperandrogenism. Fertil Steril. 1995 ; 64: 1099-1103
11. Jaatinen TA, Matinlauri I, Anttila L, et al. Serum total renin is elevated in women with polycystic ovarian syndrome. Fertil Steril. 1995 ; 63: 1000-1004
12. Hacihanefioglu B, Somunkiran A, Mahmutoglu I, et al. Effect of hypertension therapy with the angiotensin-converting enzyme inhibitor lisinopril on hyperandrogenism in women with polycystic ovary syndrome. Fertil Steril. 2002 ; 77: 526-528
13. Nawano M, Anai M, Funaki M, et al. Imidapril, an angiotensin-converting enzyme inhibitor, improves insulin sensitivity by enhancing signal transduction via insulin receptor substrate proteins and improving vascular resistance in the Zucker fatty rat. Metabolism. 1999 ; 48: 1248-1255
14. Muscogiuri G, Chavez AO, Gastaldelli A, et al. The crosstalk between insulin and renin-angiotensin-aldosterone signaling systems and its effect on glucose metabolism and diabetes prevention. Curr Vasc Pharmacol. 2008 ; 6: 301-312
15. Pollare T, Lithell H, Berne C. A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. N Engl J Med. 1989 ; 321: 868-873
16. Lobo RA. What are the key features of importance in polycystic ovary syndrome?. Fertil Steril. 2003 ; 80: 259-261
17. Rigat B, Hubert C, Alhenc-Gelas F, et al. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 1990 ; 86: 1343-1346
18. Rigat B, Hubert C, Corvol P, et al. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acids Res. 1992 ; 20: 1433
19. Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000 ; 283: 2008-2012
20. Koika V, Georgopoulos NA, Piouka A, et al. Increased frequency of the DI genotype of the angiotensin-I converting enzyme (ACE) and association of the II genotype with insulin resistance in polycystic ovary syndrome. Eur J Endocrinol. 2012 ;:
21. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986 ; 7: 177-188
22. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959 ; 22: 719-748
23. Cao Y, Wang Y, Zhou P, et al. Relationship between ACE gene polymorphism and the renin-angiotensin system in PCOS patients. Chinese Journal of Practical Gynecology and Obstetrics. 2002 ; 18: 665-666
24. Cao Y, Zhuang G. Study on the relationship between polymorphism of the angiotensin-converting-enzyme gene and polycystic ovarian syndrome. Chinese Journal of Practical Gynecology and Obstetrics. 1999 ; 15: 726-728
25. Li Q, Liu P, Xu M, et al. Angiotensin converting enzyme gene polymorphism and angiotensin converting enzyme activity in polycystic ovary syndrome. Hebei Medical Journal. 2008 ; 30: 1767
26. Karabulut A, Turgut S, Turgut G. Angiotensin converting enzyme gene insertion/deletion polymorphism in patients with polycystic ovary syndrome. Gynecol Endocrinol. 2010 ; 26: 393-398
27. Sun L, Lv H, Wei W, et al. Angiotensin-converting enzyme D/I and plasminogen activator inhibitor-1 4G/5G gene polymorphisms are associated with increased risk of spontaneous abortions in polycystic ovarian syndrome. J Endocrinol Invest. 2010 ; 33: 77-82
28. Celik O, Yesilada E, Hascalik S, et al. Angiotensin-converting enzyme gene polymorphism and risk of insulin resistance in PCOS. Reprod Biomed Online. 2010 ; 20: 492-498
29. Sun J, Fan H, Che Y, et al. Association between ACE gene I/D polymorphisms and hyperandrogenism in women with polycystic ovary syndrome (PCOS) and controls. BMC Med Genet. 2009 ; 10: 64
30. Bayram B, Kilicci C, Onlu H, et al. Association of angiotensin converting enzyme (ACE) gene I/D polymorphism and polycystic ovary syndrome (PCOS). Gene. 2011 ; 489: 86-88
31. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004 ; 19: 41-47
32. Zawadski JK, Dunaif A Polycystic ovary syndrome. Dunaif A Givens JR Haseltine FP Merriam GE Hershman SM, ed. Boston: Blackwell ; 1992: 377-384.
33. Azziz R, Carmina E, Dewailly D, et al. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril. 2009 ; 91: 456-488
34. Azziz R. Controversy in clinical endocrinology: diagnosis of polycystic ovarian syndrome: the Rotterdam criteria are premature. J Clin Endocrinol Metab. 2006 ; 91: 781-785
35. Zintzaras E, Lau J. Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches. J Clin Epidemiol. 2008 ; 61: 634-645
36. Shanmugam V, Sell KW, Saha BK. Mistyping ACE heterozygotes. PCR Methods Appl. 1993 ; 3: 120-121