Angiotensin-converting enzyme gene polymorphism and risk of insulin resistance in PCOS

Reproductive BioMedicine Online

Volumn 20, Issue 4, 2010, Pages 492-498

  Celik, Onder ^a   Yesilada, Elif ^a   Hascalik, Seyma ^a   Celik, Nilufer ^b   Sahin, Ibrahim ^a   Keskin, Lezzan ^a   Ozerol, Elif ^a  

^a INONU UNIVERSITY   (Turkey)

^b Beydagi State Hospital   (Turkey)

Author keywords

Angiotensin converting enzyme gene; Insulin resistance; PCOS; Polymorphism

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DNA; GLUCOSE; HORMONE; INSULIN; LIPID;

ADULT; ALLELE; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROL GROUP; CONTROLLED STUDY; DIET RESTRICTION; DNA EXTRACTION; ENZYME POLYMORPHISM; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC POLYMORPHISM; GENOTYPE; HOMEOSTASIS; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LEUKOCYTE; LIPID BLOOD LEVEL; OVARY POLYCYSTIC DISEASE; POLYMERASE CHAIN REACTION; RISK;

EID: 77951653085     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rbmo.2009.12.014     Document Type: Article

References (32)

1. Acosta, T.J., Berisha, B., Ozawa, T., Sato, K., Schams, D., Miyamoto, A., 1999. Evidence for a local endothelin-angiotensin-atrial natriuretic peptide systemin bovine mature follicles in vitro: effects on steroid hormones and prostaglandin secretion. Biol. Reprod. 61, 1419-1425.
2. Cao, Y., Wang, Y., Zhou, P., et al., 2002. Relationship between ACE gene polymorphism and the renin angiotensin system in PCOS patients. Chin. J. Pract. Gynecol. Obstet. 18, 665-666.
3. Celik, O., Sahin, I., Celik, N., et al., 2007. Diagnostic potential of serum N-terminal pro-B-type brain natriuretic peptide level in detection of cardiac wall stress in women with polycystic ovary syndrome: a cross-sectional comparison study. Hum. Reprod. 22, 2992-2998.
4. Christopoulos, P., Mastorakos, G., Gazouli, M., et al., 2008. Genetic variants in TCF7L2 and KCNJ11 genes in a Greek population with polycystic ovary syndrome. Gynecol. Endocrinol. 24, 486-490.
5. Diamanti-Kandarakis, E., 2006. Insulin resistance in PCOS. Endocrine 30, 13-17.
6. Echiburú, B., Pérez-Bravo, F., Maliqueo, M., et al., 2008. Polymorphism T → C (-34 base pairs) of gene CYP17 promoter in women with polycystic ovary syndrome is associated with increased body weight and insulin resistance: a preliminary study. Metabolism 5712, 1765-1771.
7. Falkner, B., Canessa, M., Anzalone, D., 1995. Effect of angiotensin converting enzyme inhibitor (Lisinopril) on insulin sensitivity and sodium transport in mild hypertension. Am. J. Hypertens. 8, 454-460.
8. Ferriman, D., Gallwey, J.D., 1962. Clinical assessment of body hair growth in women. J. Clin. Endocrinol. Metab. 21, 1440-1447.
9. Friedewald, W.T., Levy, R.I., Fredrickson, D.S., 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18, 499-502.
10. Hacihanefioglu, B., Seyisoglu, H., Karsidag, K., et al., 2000. Influence of insulin resistance on total renin level in normotensive women with polycystic ovary syndrome. Fertil. Steril. 73, 261-265.
11. Hopkins, P.N., Hunt, S.C., 2003. Genetics of hypertension. Genet. Med. 5, 413-429.
12. Jaatinen, T.A., Matinlauri, I., Anttila, L., et al., 1995. Serum total renin is elevated in women with polycystic ovarian syndrome. Fertil. Steril. 63, 1000-1004.
13. Johnson, M.C., Vega, M., Vantman, D., et al., 1997. Regulatory role of angiotensin Il on progesterone production by cultured human granulosa cells. Expression of angiotensin Il type-2 receptor. Mol. Hum. Reprod. 3, 663-668.
14. Kauma, H., Päivänsalo, M., Savolainen, M.J., et al., 1996. Association between angiotensin converting enzyme gene polymorphism and carotid atherosclerosis. J. Hypertens. 14, 1183-1187. (Pubitemid 26343496)
15. Marcondes, J.A., Hayashida, S.A., Barcellos, C.R., et al., 2007. Metabolic syndrome in women with polycystic ovary syndrome: prevalence, characteristics and predictors. Arq. Bras. Endocrinol. Metabol. 51, 972-979.
16. Matthews, D.R., Hosker, J.P., Rudenski, A.S., et al., 1985. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419.
17. Mlinar, B., Pfeifer, M., Vrtacnik-Bokal, E., et al., 2008. Reased lipin 1beta expression in visceral adipose tissue is associated with insulin resistance in polycystic ovary syndrome. Eur. J. Endocrinol. 159, 833-839.
18. Nemeth, G., Peppered, J.R., Yamada, Y., et al., 1994. The basis and evidence of a role for the ovarian renin-angiotensin system in health and disease. J. Soc. Gynecol. Invest. 1, 118-127.
19. Norman, R.J., Dewailly, D., Legro, R.S., Hickey, T.E., 2007. Polycystic ovary syndrome. Lancet 370, 685-697.
20. Orio, F., Vuolo, L., Palomba, S., et al., 2008. Metabolic and cardiovascular consequences of polycystic ovary syndrome. Minerva Ginecol. 60, 39-51. (Pubitemid 351517721)
21. Palumbo, A., Pourmotabbed, G., Carcangiu, M.L., et al., 1993. Immunohistochemical localization of renin and angiotensin Il in the ovary: comparison between normal women and patients with histologically proven polycystic ovarian disease. Fertil. Steril. 60, 280-284.
22. Pérez, M.S., Cerrone, G.E., Benencia, H., et al., 2008. Polymorphism in CYP11alpha and CYP17 genes and the etiology of hyperandrogenism in patients with polycystic ovary syndrome. Mediana 682, 129-134. (Pubitemid 351753302)
23. Pfohl, M., Fetter, M., Koch, M., et al., 1998. Association between angiotensin I-converting enzyme genotypes, extracranial artery stenosis, and stroke. Atherosclerosis 140, 161-166. (Pubitemid 28378466)
24. Rieder, M.J., Taylor, S.L., Clark, A.G., et al., 1999. Sequence variation in the human angiotensin converting enzyme. Nat. Genet. 22, 59-62.
25. Rigat, B., Hubert, C., Alhenc-Gelas, F., et al., 1990. An insertion/ deletion polymorphism in the angiotensin 1-converting enzyme gene accounting for half the variance of serum enzyme levels. J. Clin. Invest. 86, 1343-1346.
26. Saitoh, S., 2009. Insulin resistance and rennin angiotensin aldosterone system. Nippon Rinsho 67, 729-734.
27. Soubrier, F., Wei, L., Hubert, C., et al., 1993. Molecular biology of the angiotensin I converting enzyme: II. Structure-function. Gene polymorphism and clinical implications. J. Hypertens. 11, 599-604.
28. Sun, J., Fan, H., Che, Y., Cao, Y., et al., 2009. Association between ACE gene l/D polymorphisms and hyperandrogenism in women with polycystic ovary syndrome (PCOS) and controls. BMC Med. Genet. 10, 64.
29. Teede, H.J., Hutchison, S.K., Zoungas, S., 2007. The management of insulin resistance in polycystic ovary syndrome. Trends Endocrinol. Metab. 18, 273-279.
30. Townsend, R.R., Dipette, D.J., Lyeux, T.R., Wolfe, R.R., 1993. The role of the renin-angiotensin system in insulin sensitivity in normotensive subjects. Am. J. Med. Sci. 305, 67-71.
31. Van Sande, M.E., Scharpe, S.L., Neels, H.M., Van Camp, K.O., 1985. Distribution of angiotensin converting enzyme in human tissues. Clin. Chim. Acta 147, 255-260.
32. Yesilada, E., Sahin, I., Ozcan, H., et al., 2006. Increased micronucleus frequencies in peripheral blood lymphocytes in women with polycystic ovary syndrome. Eur. J. Endocrinol. 54, 563-568.