메뉴 건너뛰기




Volumn 54, Issue 9, 2013, Pages 2023-2029

The effect of chemotherapy on telomere dynamics: Clinical results and possible mechanisms

Author keywords

5 fluorouracil; Chemotherapy; Fludarabine; Hematopoietic stem cells; Lymphoma; Telomeres

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOXORUBICIN; FLUDARABINE; FLUOROURACIL; PREDNISONE; VINCRISTINE;

EID: 84882954562     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2012.757765     Document Type: Article
Times cited : (35)

References (35)
  • 1
    • 0028903635 scopus 로고
    • Hematopoietic stem cell compartment:Acute and late eff ects of radiation therapy and chemotherapy
    • P,Constine L, Greenberger J, et al. Hematopoietic stem cell compartment:Acute and late eff ects of radiation therapy and chemotherapy. Int J Radiat Oncol Biol Phys 1995;31:1319-1339.
    • (1995) Int J Radiat Oncol Biol Phys , vol.31 , pp. 1319-1339
    • Pconstine, L.1    Greenberger, J.2
  • 2
    • 0025138652 scopus 로고
    • 5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation
    • Lerner C, Harrison DE. 5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation. Exp Hematol 1990;18:114-118.
    • (1990) Exp Hematol , vol.18 , pp. 114-118
    • Lerner, C.1    Harrison, D.E.2
  • 3
    • 0018655416 scopus 로고
    • Properties of haematopoietic stem cells surviving 5-fluorouracil treatment: Evidence for a pre-CFU-S cell?
    • Hodgson GS, Bradley TR. Properties of haematopoietic stem cells surviving 5-fluorouracil treatment: Evidence for a pre-CFU-S cell? Nature 1979;281:381-382.
    • (1979) Nature , vol.281 , pp. 381-382
    • Hodgson, G.S.1    Bradley, T.R.2
  • 4
    • 56249094143 scopus 로고    scopus 로고
    • Preferential sensitivity of hematopoietic (HPs) and mesenchymal (MPs) progenitors to fludarabine suggests impaired bone marrow niche and HP mobilization
    • Berger MG, Berger J, Richard C, et al. Preferential sensitivity of hematopoietic (HPs) and mesenchymal (MPs) progenitors to fludarabine suggests impaired bone marrow niche and HP mobilization. Leukemia 2008;22:2131-2134.
    • (2008) Leukemia , vol.22 , pp. 2131-2134
    • Berger, M.G.1    Berger, J.2    Richard, C.3
  • 5
    • 33749502961 scopus 로고    scopus 로고
    • Cytokines and hematopoietic stem cell mobilization
    • Nervi B, Link DC, DiPersio JF. Cytokines and hematopoietic stem cell mobilization. J Cell Biochem 2006;99:690-705.
    • (2006) J Cell Biochem , vol.99 , pp. 690-705
    • Nervi, B.1    Link, D.C.2    Dipersio, J.F.3
  • 6
    • 59949101341 scopus 로고    scopus 로고
    • Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation for lymphoma
    • Chakraborty S, Sun CL, Francisco L, et al. Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation for lymphoma. J Clin Oncol 2009;27:791-798.
    • (2009) J Clin Oncol , vol.27 , pp. 791-798
    • Chakraborty, S.1    Sun, C.L.2    Francisco, L.3
  • 7
    • 0015515155 scopus 로고
    • Origin of concatemeric T7 DNA
    • Watson JD. Origin of concatemeric T7 DNA. Nat New Biol 1972;239:197-201.
    • (1972) Nat New Biol , vol.239 , pp. 197-201
    • Watson, J.D.1
  • 8
    • 0027762451 scopus 로고
    • Telomere reduction in giant cell tumor of bone and with aging
    • Schwartz HS, Dahir GA, Butler MG. Telomere reduction in giant cell tumor of bone and with aging. Cancer Genet Cytogenet 1993;71:132-138.
    • (1993) Cancer Genet Cytogenet , vol.71 , pp. 132-138
    • Schwartz, H.S.1    Dahir, G.A.2    Butler, M.G.3
  • 9
    • 0025143252 scopus 로고
    • Telomere reduction in human colorectal carcinoma and with ageing
    • Hastie ND, Dempster M, Dunlop MG, et al. Telomere reduction in human colorectal carcinoma and with ageing. Nature 1990;346:866-868.
    • (1990) Nature , vol.346 , pp. 866-868
    • Hastie, N.D.1    Dempster, M.2    Dunlop, M.G.3
  • 10
    • 0027486732 scopus 로고
    • Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
    • Vaziri H, Schachter F, UchidaI, et al. Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet 1993;52:661-667.
    • (1993) Am J Hum Genet , vol.52 , pp. 661-667
    • Vaziri, H.1    Uchidai, S.F.2
  • 11
    • 0032171293 scopus 로고    scopus 로고
    • Comparison of chromosome telomere integrity in multiple tissues from subjects at diff erent ages
    • Butler MG, Tilburt J, DeVries A, et al. Comparison of chromosome telomere integrity in multiple tissues from subjects at diff erent ages. Cancer Genet Cytogenet 1998;105:138-144.
    • (1998) Cancer Genet Cytogenet , vol.105 , pp. 138-144
    • Butler, M.G.1    Tilburt, J.2    Devries, A.3
  • 12
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985;43:405-413
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 13
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994;266:2011-2015.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 14
    • 0031809832 scopus 로고    scopus 로고
    • Expression of TERT in early premalignant lesions and a subset of cells in normal tissues
    • Kolquist KA, Ellisen LW,Counter CM, et al. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nat Genet 1998;19:182-186.
    • (1998) Nat Genet , vol.19 , pp. 182-186
    • Kolquist, K.A.1    Ellisen Lwcounter, C.M.2
  • 15
    • 0028077099 scopus 로고
    • Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
    • Vaziri H, Dragowska W, Allsopp RC, et al. Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age. Proc Natl Acad Sci USA 1994;91:9857-9860.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9857-9860
    • Vaziri, H.1    Dragowska, W.2    Allsopp, R.C.3
  • 16
    • 0142258907 scopus 로고    scopus 로고
    • Telomere length in subpopulations of human hematopoietic cells
    • Van Ziffle JA, Baerlocher GM, Lansdorp PM. Telomere length in subpopulations of human hematopoietic cells. Stem Cells 2003;21:654-660.
    • (2003) Stem Cells , vol.21 , pp. 654-660
    • Van Ziffle, J.A.1    Baerlocher, G.M.2    Lansdorp, P.M.3
  • 17
    • 0032539451 scopus 로고    scopus 로고
    • Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants
    • Wynn RF, Cross MA, Hatton C, et al. Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants. Lancet 1998;351:178-181.
    • (1998) Lancet , vol.351 , pp. 178-181
    • Wynn, R.F.1    Cross, M.A.2    Hatton, C.3
  • 18
    • 0035863831 scopus 로고    scopus 로고
    • Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation
    • Rufer N, Brummendorf TH, Chapuis B, et al. Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation. Blood 2001;97:575-577.
    • (2001) Blood , vol.97 , pp. 575-577
    • Rufer, N.1    Brummendorf, T.H.2    Chapuis, B.3
  • 19
    • 0034932138 scopus 로고    scopus 로고
    • Accelerated telomere shortening following allogeneic transplantation is independent of the cell source and occurs within the first year post transplant
    • Robertson JD, Testa NG,Russell N H, et al. Accelerated telomere shortening following allogeneic transplantation is independent of the cell source and occurs within the first year post transplant. Bone Marrow Transplant 2001;27:1283-1286.
    • (2001) Bone Marrow Transplant , vol.27 , pp. 1283-1286
    • Robertson, J.D.1    Testa Ngrussell, N.H.2
  • 20
    • 0036178874 scopus 로고    scopus 로고
    • Long-term follow-up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem cell exhaustion
    • de Pauw ES, Otto SA, Wijnen JT, et al. Long-term follow-up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem cell exhaustion. Br J Haematol 2002;116:491-496.
    • (2002) Br J Haematol , vol.116 , pp. 491-496
    • De Pauw, E.S.1    Otto, S.A.2    Wijnen, J.T.3
  • 21
    • 27644441386 scopus 로고    scopus 로고
    • Nonmyeloablative conditioning does not prevent telomere shortening after allogeneic stem cell transplantation
    • Lahav M, Uziel O, Kestenbaum M, et al. Nonmyeloablative conditioning does not prevent telomere shortening after allogeneic stem cell transplantation. Transplantation 2005;80:969-976.
    • (2005) Transplantation , vol.80 , pp. 969-976
    • Lahav, M.1    Uziel, O.2    Kestenbaum, M.3
  • 22
    • 0034002285 scopus 로고    scopus 로고
    • Shortening of telomeres in recipients of both autologous and allogeneic hematopoietic stem cell transplantation
    • Akiyama M, Asai O, Kuraishi Y, et al. Shortening of telomeres in recipients of both autologous and allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant 2000;25:441-447.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 441-447
    • Akiyama, M.1    Asai, O.2    Kuraishi, Y.3
  • 23
    • 0031962410 scopus 로고    scopus 로고
    • Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy
    • Engelhardt M, Ozkaynak MF, Drullinsky P, et al. Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy. Leukemia 1998;12:13-24.
    • (1998) Leukemia , vol.12 , pp. 13-24
    • Engelhardt, M.1    Ozkaynak, M.F.2    Drullinsky, P.3
  • 24
    • 0037325715 scopus 로고    scopus 로고
    • Telomere dynamics in childhood leukemia and solid tumors :A follow-up study
    • Franco S, Ozkaynak MF, Sandoval C, et al. Telomere dynamics in childhood leukemia and solid tumors :A follow-up study. Leukemia 2003;17:401-410.
    • (2003) Leukemia , vol.17 , pp. 401-410
    • Franco, S.1    Ozkaynak, M.F.2    Sandoval, C.3
  • 25
    • 0037278402 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor administration upregulates telomerase activity in CD34 haematopoietic cells and may prevent telomere attrition after chemotherapy
    • M
    • M, Uziel O, Shapiro H, et al. Granulocyte colony-stimulating factor administration upregulates telomerase activity in CD34 haematopoietic cells and may prevent telomere attrition after chemotherapy. Br J Haematol 2003;120:329-336.
    • (2003) Br J Haematol , vol.120 , pp. 329-336
    • Uziel, O.1    Shapiro, H.2
  • 26
    • 0042856752 scopus 로고    scopus 로고
    • Telomere length shortening in non-Hodgkin's lymphoma patients undergoing chemotherapy
    • Lee JJ, Nam CE, Cho SH, et al. Telomere length shortening in non-Hodgkin's lymphoma patients undergoing chemotherapy. Ann Hematol 2003;82:492-495.
    • (2003) Ann Hematol , vol.82 , pp. 492-495
    • Lee, J.J.1    Nam, C.E.2    Cho, S.H.3
  • 27
    • 33751303787 scopus 로고    scopus 로고
    • Acceleration of telomere loss by chemotherapy is greater in older patients with locally advanced head and neck cancer
    • Unryn BM, Hao D,Gl?ck S, et al. Acceleration of telomere loss by chemotherapy is greater in older patients with locally advanced head and neck cancer. Clin Cancer Res 2006;12:6345-6350.
    • (2006) Clin Cancer Res , vol.12 , pp. 6345-6350
    • Unryn, B.M.1    Hao, D.2    Glck, S.3
  • 28
    • 34347324094 scopus 로고    scopus 로고
    • Telomere length shortening of peripheral blood mononuclear cells in solid-cancer patients undergoing standard-dose chemotherapy might be correlated with good treatment response and neutropenia severity
    • Yoon SY, Sung HJ, Park KH, et al. Telomere length shortening of peripheral blood mononuclear cells in solid-cancer patients undergoing standard-dose chemotherapy might be correlated with good treatment response and neutropenia severity. Acta Haematol 2007;118:30-37.
    • (2007) Acta Haematol , vol.118 , pp. 30-37
    • Yoon, S.Y.1    Sung, H.J.2    Park, K.H.3
  • 29
    • 0035906808 scopus 로고    scopus 로고
    • Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation
    • Schruder CP, Wisman GB, de Jong S, et al. Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation. Br J Cancer 2001;84:1348-1353.
    • (2001) Br J Cancer , vol.84 , pp. 1348-1353
    • Schruder, C.P.1    Wisman, G.B.2    De Jong, S.3
  • 30
    • 0027238836 scopus 로고
    • Post-5-fluorouracil human marrow: Stem cell characteristics and renewal properties after autologous marrow transplantation
    • Stewart FM, Temeles D, Lowry P, et al. Post-5-fluorouracil human marrow: Stem cell characteristics and renewal properties after autologous marrow transplantation. Blood 1993;81:2283-2289.
    • (1993) Blood , vol.81 , pp. 2283-2289
    • Stewart, F.M.1    Temeles, D.2    Lowry, P.3
  • 31
    • 0033002175 scopus 로고    scopus 로고
    • Fludarabine-containing regimens severely impair peripheral blood stem cells mobilization and collection in acute myeloid leukaemia patients
    • Visani G, Lemoli RM, Tosi P, et al. Fludarabine-containing regimens severely impair peripheral blood stem cells mobilization and collection in acute myeloid leukaemia patients. Br J Haematol 1999;105:775-779.
    • (1999) Br J Haematol , vol.105 , pp. 775-779
    • Visani, G.1    Lemoli, R.M.2    Tosi, P.3
  • 32
    • 0036786653 scopus 로고    scopus 로고
    • Telomere length in haemopoietic stem cells can be determined from that of mononuclear blood cells or whole blood
    • Sakoff JA, De Waal E, Garg MB, et al. Telomere length in haemopoietic stem cells can be determined from that of mononuclear blood cells or whole blood. Leuk Lymphoma 2002;43:2017-2020.
    • (2002) Leuk Lymphoma , vol.43 , pp. 2017-2020
    • Sakoff, J.A.1    De Waal, E.2    Garg, M.B.3
  • 33
    • 0031879115 scopus 로고    scopus 로고
    • Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
    • Rufer ND, Thornbury G, Roosnek E, et al. Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. Nat Biotechnol 1998;16:743-747.
    • (1998) Nat Biotechnol , vol.16 , pp. 743-747
    • Rufer, N.D.1    Thornbury, G.2    Roosnek, E.3
  • 34
    • 0031858734 scopus 로고    scopus 로고
    • Telomere length, telomerase activity and telomerase RNA expression in human esophageal cancer cells: Correlation with cell proliferation, diff erentiation and chemosensitivity to anticancer drugs
    • Asai A, Kiyozuka Y, Yoshida R, et al. Telomere length, telomerase activity and telomerase RNA expression in human esophageal cancer cells: Correlation with cell proliferation, diff erentiation and chemosensitivity to anticancer drugs. Anticancer Res 1998;18:1465-1472.
    • (1998) Anticancer Res , vol.18 , pp. 1465-1472
    • Asai, A.1    Kiyozuka, Y.2    Yoshida, R.3
  • 35
    • 0037221969 scopus 로고    scopus 로고
    • Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood stem cell transplantation
    • Roelofs H, de Pauw ES, Zwinderman AH, et al. Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood stem cell transplantation. Blood 2003;101:358-362.
    • (2003) Blood , vol.101 , pp. 358-362
    • Roelofs, H.1    De Pauw, E.S.2    Zwinderman, A.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.