메뉴 건너뛰기




Volumn , Issue , 2013, Pages 45-61

Translating Pharmacogenomic Research to Therapeutic Potentials

Author keywords

Personalized medicine, biomarker, genomic technologies

Indexed keywords


EID: 84882864516     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-391918-2.00002-0     Document Type: Chapter
Times cited : (2)

References (42)
  • 1
    • 84882837149 scopus 로고    scopus 로고
    • University of Florida Clinical and Translational Science Institute: transformation and translation in personalized medicine
    • Nelson DR, Conlon M, Baralt C, et al. University of Florida Clinical and Translational Science Institute: transformation and translation in personalized medicine. Clin Transl Sci.
    • Clin Transl Sci
    • Nelson, D.R.1    Conlon, M.2    Baralt, C.3
  • 2
    • 84862620703 scopus 로고    scopus 로고
    • Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT Project
    • Pulley J.M., Denny J.C., Peterson J.F., Bernard G.R., Vnencak-Jones C.L., Ramirez A.H., et al. Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT Project. Clin Pharmacol Ther 2012, 92:87-95.
    • (2012) Clin Pharmacol Ther , vol.92 , pp. 87-95
    • Pulley, J.M.1    Denny, J.C.2    Peterson, J.F.3    Bernard, G.R.4    Vnencak-Jones, C.L.5    Ramirez, A.H.6
  • 3
    • 0031594223 scopus 로고    scopus 로고
    • The dopamine D3 receptor (DRD3) Ser9Gly polymorphism and schizophrenia: a haplotype relative risk study and association with clozapine response
    • Malhotra A.K., Goldman D., Buchanan R.W., Rooney W., Clifton A., Kosmidis M.H., et al. The dopamine D3 receptor (DRD3) Ser9Gly polymorphism and schizophrenia: a haplotype relative risk study and association with clozapine response. Mol Psychiatry 1998, 3:72-75.
    • (1998) Mol Psychiatry , vol.3 , pp. 72-75
    • Malhotra, A.K.1    Goldman, D.2    Buchanan, R.W.3    Rooney, W.4    Clifton, A.5    Kosmidis, M.H.6
  • 4
    • 0031822689 scopus 로고    scopus 로고
    • A functional serotonin transporter (5-HTT) polymorphism is associated with psychosis in neuroleptic-free schizophrenics
    • Malhotra A.K., Goldman D., Mazzanti C., Clifton A., Breier A., Pickar D. A functional serotonin transporter (5-HTT) polymorphism is associated with psychosis in neuroleptic-free schizophrenics. Mol Psychiatry 1998, 3:328-332.
    • (1998) Mol Psychiatry , vol.3 , pp. 328-332
    • Malhotra, A.K.1    Goldman, D.2    Mazzanti, C.3    Clifton, A.4    Breier, A.5    Pickar, D.6
  • 5
    • 0029790119 scopus 로고    scopus 로고
    • Lack of association between polymorphisms in the 5-HT2A receptor gene and the antipsychotic response to clozapine
    • Malhotra A.K., Goldman D., Ozaki N., Breier A., Buchanan R., Pickar D. Lack of association between polymorphisms in the 5-HT2A receptor gene and the antipsychotic response to clozapine. Am J Psychiatry 1996, 153:1092-1094.
    • (1996) Am J Psychiatry , vol.153 , pp. 1092-1094
    • Malhotra, A.K.1    Goldman, D.2    Ozaki, N.3    Breier, A.4    Buchanan, R.5    Pickar, D.6
  • 8
    • 0032962216 scopus 로고    scopus 로고
    • CYP2D6 status of extensive metabolizers after multiple-dose fluoxetine, fluvoxamine, paroxetine, or sertraline
    • Alfaro C.L., Lam Y.W., Simpson J., Ereshefsky L. CYP2D6 status of extensive metabolizers after multiple-dose fluoxetine, fluvoxamine, paroxetine, or sertraline. J Clin Psychopharmacol 1999, 19:155-163.
    • (1999) J Clin Psychopharmacol , vol.19 , pp. 155-163
    • Alfaro, C.L.1    Lam, Y.W.2    Simpson, J.3    Ereshefsky, L.4
  • 9
    • 43949096582 scopus 로고    scopus 로고
    • Inflammation and altered drug clearance in cancer: transcriptional repression of a human CYP3A4 transgene in tumor-bearing mice
    • Robertson G.R., Liddle C., Clarke S.J. Inflammation and altered drug clearance in cancer: transcriptional repression of a human CYP3A4 transgene in tumor-bearing mice. Clin Pharmacol Ther 2008, 83:894-897.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 894-897
    • Robertson, G.R.1    Liddle, C.2    Clarke, S.J.3
  • 10
    • 84882875635 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention Genetic testing: ACCE model system for collecting, analyzing and disseminating information on genetic tests, Accessed March 26, 2012
    • Centers for Disease Control and Prevention Genetic testing: ACCE model system for collecting, analyzing and disseminating information on genetic tests Accessed March 26, 2012. http://www.cdc.gov/genomics/gtesting/ACCE/FBR/index.htm.
  • 11
    • 37349093041 scopus 로고    scopus 로고
    • EGAPP Working Group Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors
    • EGAPP Working Group Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors. Genet Med 2007, 9:819-825.
    • (2007) Genet Med , vol.9 , pp. 819-825
  • 12
    • 77955425743 scopus 로고    scopus 로고
    • ACCF/AHA Clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association
    • Holmes D.R., Dehmer G.J., Kaul S., Leifer D., O'Gara P.T., Stein C.M. ACCF/AHA Clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association. Circulation 2010, 122:537-557.
    • (2010) Circulation , vol.122 , pp. 537-557
    • Holmes, D.R.1    Dehmer, G.J.2    Kaul, S.3    Leifer, D.4    O'Gara, P.T.5    Stein, C.M.6
  • 13
    • 83155181393 scopus 로고    scopus 로고
    • ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions
    • Levine G.N., Bates E.R., Blankenship J.C., Bailey S.R., Bittl J.A., Cercek B., et al. ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. Circulation 2011, 124:2574-2609.
    • (2011) Circulation , vol.124 , pp. 2574-2609
    • Levine, G.N.1    Bates, E.R.2    Blankenship, J.C.3    Bailey, S.R.4    Bittl, J.A.5    Cercek, B.6
  • 14
    • 0036220552 scopus 로고    scopus 로고
    • Impact of CYP2C9 and CYP2C19 polymorphisms on tolbutamide kinetics and the insulin and glucose response in healthy volunteers
    • Kirchheiner J., Bauer S., Meineke I., Rohde W., Prang V., Meisel C., et al. Impact of CYP2C9 and CYP2C19 polymorphisms on tolbutamide kinetics and the insulin and glucose response in healthy volunteers. Pharmacogenetics 2002, 12:101-109.
    • (2002) Pharmacogenetics , vol.12 , pp. 101-109
    • Kirchheiner, J.1    Bauer, S.2    Meineke, I.3    Rohde, W.4    Prang, V.5    Meisel, C.6
  • 15
    • 33947375710 scopus 로고    scopus 로고
    • Pharmacogenomics-based tailored versus standard therapeutic regimen for eradication of H. pylori
    • Furuta T., Shirai N., Kodaira M., Sugimoto M., Nogaki A., Kuriyama S., et al. Pharmacogenomics-based tailored versus standard therapeutic regimen for eradication of H. pylori. Clin Pharmacol Ther 2007, 81:521-528.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 521-528
    • Furuta, T.1    Shirai, N.2    Kodaira, M.3    Sugimoto, M.4    Nogaki, A.5    Kuriyama, S.6
  • 16
    • 84864101032 scopus 로고    scopus 로고
    • Cost-effectiveness of cytochrome P450 2C19 genotype screening for selection of antiplatelet therapy with clopidogrel or prasugrel
    • Reese E.S., Daniel Mullins C., Beitelshees A.L., Onukwugha E. Cost-effectiveness of cytochrome P450 2C19 genotype screening for selection of antiplatelet therapy with clopidogrel or prasugrel. Pharmacotherapy 2012, 32:323-332.
    • (2012) Pharmacotherapy , vol.32 , pp. 323-332
    • Reese, E.S.1    Daniel Mullins, C.2    Beitelshees, A.L.3    Onukwugha, E.4
  • 17
    • 58749095297 scopus 로고    scopus 로고
    • Cost-effectiveness of using pharmacogenetic information in warfarin dosing for patients with nonvalvular atrial fibrillation
    • Eckman M.H., Rosand J., Greenberg S.M., Gage B.F. Cost-effectiveness of using pharmacogenetic information in warfarin dosing for patients with nonvalvular atrial fibrillation. Ann Intern Med 2009, 150:73-83.
    • (2009) Ann Intern Med , vol.150 , pp. 73-83
    • Eckman, M.H.1    Rosand, J.2    Greenberg, S.M.3    Gage, B.F.4
  • 18
    • 70350221662 scopus 로고    scopus 로고
    • Potential clinical and economic outcomes of CYP2C9 and VKORC1 genotype-guided dosing in patients starting warfarin therapy
    • You J.H., Tsui K.K., Wong R.S., Cheng G. Potential clinical and economic outcomes of CYP2C9 and VKORC1 genotype-guided dosing in patients starting warfarin therapy. Clin Pharmacol Ther 2009, 86:540-547.
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 540-547
    • You, J.H.1    Tsui, K.K.2    Wong, R.S.3    Cheng, G.4
  • 20
    • 84860538806 scopus 로고    scopus 로고
    • Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial
    • Roberts J.D., Wells G.A., Le May M.R., Labinaz M., Glover C., Froeschl M., et al. Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial. Lancet 2012, 379:1705-1711.
    • (2012) Lancet , vol.379 , pp. 1705-1711
    • Roberts, J.D.1    Wells, G.A.2    Le May, M.R.3    Labinaz, M.4    Glover, C.5    Froeschl, M.6
  • 22
    • 47949086046 scopus 로고    scopus 로고
    • Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
    • Gage B.F., Eby C., Johnson J.A., Deych E., Rieder M.J., Ridker P.M., et al. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther 2008, 84:326-331.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 326-331
    • Gage, B.F.1    Eby, C.2    Johnson, J.A.3    Deych, E.4    Rieder, M.J.5    Ridker, P.M.6
  • 23
    • 42049109764 scopus 로고    scopus 로고
    • PharmGKB and the International Warfarin Pharmacogenetics Consortium: the changing role for pharmacogenomic databases and single-drug pharmacogenetics
    • Owen R.P., Altman R.B., Klein T.E. PharmGKB and the International Warfarin Pharmacogenetics Consortium: the changing role for pharmacogenomic databases and single-drug pharmacogenetics. Hum Mutat 2008, 29:456-460.
    • (2008) Hum Mutat , vol.29 , pp. 456-460
    • Owen, R.P.1    Altman, R.B.2    Klein, T.E.3
  • 24
    • 84882928484 scopus 로고    scopus 로고
    • Accessed April 17, 2012, IWPC Pharmacogenetic Dosing Algorithm
    • IWPC Pharmacogenetic Dosing Algorithm Accessed April 17, 2012. http://pharmgkb.org/drug/PA451906.
  • 25
    • 84871351017 scopus 로고    scopus 로고
    • Accessed April 17, 2012
    • WarfarinDosing Accessed April 17, 2012. http://www.warfarindosing.org.
    • WarfarinDosing
  • 26
    • 42349108153 scopus 로고    scopus 로고
    • Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients
    • Michaud V., Vanier M.C., Brouillette D., Roy D., Verret L., Noel N., et al. Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients. Clin Pharmacol Ther 2008, 83:740-748.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 740-748
    • Michaud, V.1    Vanier, M.C.2    Brouillette, D.3    Roy, D.4    Verret, L.5    Noel, N.6
  • 27
    • 42449136621 scopus 로고    scopus 로고
    • Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: comparison with other equations
    • Wu A.H., Wang P., Smith A., Haller C., Drake K., Linder M., et al. Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: comparison with other equations. Pharmacogenomics 2008, 9:169-178.
    • (2008) Pharmacogenomics , vol.9 , pp. 169-178
    • Wu, A.H.1    Wang, P.2    Smith, A.3    Haller, C.4    Drake, K.5    Linder, M.6
  • 30
    • 84855968708 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype
    • Crews K.R., Gaedigk A., Dunnenberger H.M., Klein T.E., Shen D.D., Callaghan J.T., et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin Pharmacol Ther 2012, 91:321-326.
    • (2012) Clin Pharmacol Ther , vol.91 , pp. 321-326
    • Crews, K.R.1    Gaedigk, A.2    Dunnenberger, H.M.3    Klein, T.E.4    Shen, D.D.5    Callaghan, J.T.6
  • 31
    • 80052962391 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing
    • Johnson J.A., Gong L., Whirl-Carrillo M., Gage B.F., Scott S.A., Stein C.M., et al. Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing. Clin Pharmacol Ther 2011, 90:625-629.
    • (2011) Clin Pharmacol Ther , vol.90 , pp. 625-629
    • Johnson, J.A.1    Gong, L.2    Whirl-Carrillo, M.3    Gage, B.F.4    Scott, S.A.5    Stein, C.M.6
  • 32
    • 84858798082 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing
    • Martin M.A., Klein T.E., Dong B.J., Pirmohamed M., Haas D.W., Kroetz D.L. Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing. Clin Pharmacol Ther 2012, 91:734-738.
    • (2012) Clin Pharmacol Ther , vol.91 , pp. 734-738
    • Martin, M.A.1    Klein, T.E.2    Dong, B.J.3    Pirmohamed, M.4    Haas, D.W.5    Kroetz, D.L.6
  • 33
    • 79960613122 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy
    • Scott S.A., Sangkuhl K., Gardner E.E., Stein C.M., Hulot J.S., Johnson J.A., et al. Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy. Clin Pharmacol Ther 2011, 90:328-332.
    • (2011) Clin Pharmacol Ther , vol.90 , pp. 328-332
    • Scott, S.A.1    Sangkuhl, K.2    Gardner, E.E.3    Stein, C.M.4    Hulot, J.S.5    Johnson, J.A.6
  • 34
    • 84862600938 scopus 로고    scopus 로고
    • The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy
    • Wilke R.A., Ramsey L.B., Johnson S.G., Maxwell W.D., McLeod H.L., Voora D., et al. The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy. Clin Pharmacol Ther 2012, 92:112-117.
    • (2012) Clin Pharmacol Ther , vol.92 , pp. 112-117
    • Wilke, R.A.1    Ramsey, L.B.2    Johnson, S.G.3    Maxwell, W.D.4    McLeod, H.L.5    Voora, D.6
  • 35
    • 84882922442 scopus 로고    scopus 로고
    • Food and Drug Administration Guidance on pharmacogenetic tests and genetic tests for heritable markers, Accessed April 16, 2012
    • Food and Drug Administration Guidance on pharmacogenetic tests and genetic tests for heritable markers Accessed April 16, 2012. http://www.fda.gov/MedicalDevices/DeviceRegulationsandGuidance/GuidanceD ocuments/ucm077862.htm.
  • 36
    • 1542503725 scopus 로고    scopus 로고
    • HER-2 testing and trastuzumab therapy for metastatic breast cancer: a cost-effectiveness analysis
    • Elkin E.B., Weinstein M.C., Winer E.P., Kuntz K.M., Schnitt S.J., Weeks J.C. HER-2 testing and trastuzumab therapy for metastatic breast cancer: a cost-effectiveness analysis. J Clin Oncol 2004, 22:854-863.
    • (2004) J Clin Oncol , vol.22 , pp. 854-863
    • Elkin, E.B.1    Weinstein, M.C.2    Winer, E.P.3    Kuntz, K.M.4    Schnitt, S.J.5    Weeks, J.C.6
  • 37
    • 84881191075 scopus 로고    scopus 로고
    • Clinical and economic challenges facing pharmacogenomics
    • [Epub date is Jan 11, 2012]
    • Cohen J., Wilson A., Manzolillo K. Clinical and economic challenges facing pharmacogenomics. Pharmacogenomics J 2012, [Epub date is Jan 11, 2012]. 10.1038/tpj.2011.63.
    • (2012) Pharmacogenomics J
    • Cohen, J.1    Wilson, A.2    Manzolillo, K.3
  • 38
    • 52449133413 scopus 로고    scopus 로고
    • Assessing the value-adding impact of diagnostic-type tests on drug development and marketing
    • Blair E.D. Assessing the value-adding impact of diagnostic-type tests on drug development and marketing. Mol Diagn Ther 2008, 12:331-337.
    • (2008) Mol Diagn Ther , vol.12 , pp. 331-337
    • Blair, E.D.1
  • 40
    • 41149120561 scopus 로고    scopus 로고
    • A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions
    • Janssens A.C., Gwinn M., Bradley L.A., Oostra B.A., van Duijn C.M., et al. A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions. Am J Hum Genet 2008, 82:593-599.
    • (2008) Am J Hum Genet , vol.82 , pp. 593-599
    • Janssens, A.C.1    Gwinn, M.2    Bradley, L.A.3    Oostra, B.A.4    van Duijn, C.M.5
  • 42
    • 77955082302 scopus 로고    scopus 로고
    • A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury
    • Singer J.B., Lewitzky S., Leroy E., Yang F., Zhao X., Klickstein L., et al. A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat Genet 2010, 42:711-714.
    • (2010) Nat Genet , vol.42 , pp. 711-714
    • Singer, J.B.1    Lewitzky, S.2    Leroy, E.3    Yang, F.4    Zhao, X.5    Klickstein, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.