Prodrugs of N-dicarboximide derivatives of the rat selective toxicant norbormide

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 18, 2013, Pages 5886-5899

  Rennison, David ^a   Laita, Olivia ^a   Conole, Daniel ^a   Jay Smith, Morgan ^a   Knauf, Jan ^b   Bova, Sergio ^c   Cavalli, Maurizio ^c   Hopkins, Brian ^c   Linthicum, Darwin S ^c   Brimble, Margaret A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF PADOVA   (Italy)

^c LANDCARE RESEARCH   (New Zealand)

Author keywords

Norbormide; Prodrug; Rat toxicant; Raticide; Rodenticide

Indexed keywords

5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) N 2' SEBACOYLOXYETHYL 5 NORBORNENE 2,3 DICARBOXIMIDE DIMER; 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) N 2' ALPHA METHYLCINNAMOYLOXYETHYL 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) N 2' OCTANOYLOXYETHYL 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) N 2' PHENYLPROPIOYLOXYETHYL 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) N [2' (4'' ISOPROPYLCINNAMOYLOXY)ETHYL] 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) N [2' (4'' METHOXYCINNAMOYLOXY)ETHYL] 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) N OCTYLOXYCARBONYLMETHYL 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N 2' AMINOETHYL 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N 2' DIPHENYLACETYLOXYETHYL 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N 2' DODECANAMIDOETHYL ETHYL 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N 2' HYDROXYETHYL 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N 3' CINNAMOYLOXYPROPYL 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N 3' HYDROXYPROPYL 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N [2' (4'' ETHOXYCINNAMAMIDO)ETHYL] 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N [2' (4'' ETHYLCINNAMOYLOXY)ETHYL] 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N [2' ETHYLENEBIS(HYDROGENSUCCINOYLOXY)ETHYL] 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE DIMER; N CARBOXYMETHYL 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N CINNAMOXYCARBONYLMETHYL 5 (ALPHA HYDROXY ALPHA 2 PYRIDYLBENZYL) 7 (ALPHA 2 PYRIDYLBENZYLIDENE) 5 NORBORNENE 2,3 DICARBOXIMIDE; N DICARBOXIMIDE DERIVATIVE; NORBORMIDE; PESTICIDE; PRODRUG; RODENTICIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL PEST CONTROL; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME BLOOD LEVEL; ENZYME MODIFICATION; ENZYME STABILITY; FEMALE; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; LETHALITY; LIVER PARENCHYMA; MALE; NONHUMAN; PALATABILITY; RAT; STEREOISOMERISM; VASOCONSTRICTION;

MAMMALIA; RATTUS; RODENTIA;

NORBORMIDE; PRODRUG; RAT TOXICANT; RATICIDE; RODENTICIDE;

ANIMALS; AORTA; HYDROLYSIS; IMIDES; LIVER; MALE; MUSCLE CONTRACTION; NORBORNANES; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR;

EID: 84882813169     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.06.071     Document Type: Article

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