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Volumn 140, Issue 3, 2013, Pages 370-378

CD105 (endoglin) is highly overexpressed in a subset of cases of acute myeloid leukemias

Author keywords

Acute myeloid leukemia; CD105; Endoglin; IDH2 mutation; Immunohistochemistry

Indexed keywords

ENDOGLIN; MESSENGER RNA;

EID: 84882795736     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPG8XH7ZONAKXK     Document Type: Article
Times cited : (16)

References (40)
  • 1
    • 0025310515 scopus 로고
    • Primary structure of endoglin, an rgd-containing glycoprotein of human endothelial cells
    • Gougos A, Letarte M. Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells. J Biol Chem. 1990;265:8361-8364.
    • (1990) J Biol Chem. , vol.265 , pp. 8361-8364
    • Gougos, A.1    Letarte, M.2
  • 2
  • 3
    • 42249110348 scopus 로고    scopus 로고
    • Endoglin (cd105): A marker of tumor vasculature and potential target for therapy
    • Dallas NA, Samuel S, Xia L, et al. Endoglin (CD105): a marker of tumor vasculature and potential target for therapy. Clin Cancer Res. 2008;14:1931-1937.
    • (2008) Clin Cancer Res. , vol.14 , pp. 1931-1937
    • Dallas, N.A.1    Samuel, S.2    Xia, L.3
  • 4
    • 38149133230 scopus 로고    scopus 로고
    • Endoglin-mediated vascular remodeling: Mechanisms underlying hereditary hemorrhagic telangiectasia
    • Lebrin F, Mummery CL. Endoglin-mediated vascular remodeling: mechanisms underlying hereditary hemorrhagic telangiectasia. Trends Cardiovasc Med. 2008;18:25-32.
    • (2008) Trends Cardiovasc Med. , vol.18 , pp. 25-32
    • Lebrin, F.1    Mummery, C.L.2
  • 5
    • 0035017536 scopus 로고    scopus 로고
    • Endoglin: An accessory component of the tgf-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies
    • Fonsatti E, Del Vecchio L, Altomonte M, et al. Endoglin: an accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies. J Cell Physiol. 2001;188:1-7.
    • (2001) J Cell Physiol. , vol.188 , pp. 1-7
    • Fonsatti, E.1    Del Vecchio, L.2    Altomonte, M.3
  • 6
    • 84865766360 scopus 로고    scopus 로고
    • A phase i first-inhuman study of trc105 (anti-endoglin antibody) in patients with advanced cancer
    • Rosen LS, Hurwitz HI, Wong MK, et al. A phase I first-inhuman study of TRC105 (anti-endoglin antibody) in patients with advanced cancer. Clin Cancer Res. 2012;18:4820-4829.
    • (2012) Clin Cancer Res. , vol.18 , pp. 4820-4829
    • Rosen, L.S.1    Hurwitz, H.I.2    Wong, M.K.3
  • 7
    • 0029035687 scopus 로고
    • Differential expression of endoglin on fetal and adult hematopoietic cells in human bone marrow
    • Rokhlin OW, Cohen MB, Kubagawa H, et al. Differential expression of endoglin on fetal and adult hematopoietic cells in human bone marrow. J Immunol. 1995;154:4456-4465.
    • (1995) J Immunol. , vol.154 , pp. 4456-4465
    • Rokhlin, O.W.1    Cohen, M.B.2    Kubagawa, H.3
  • 9
    • 77649274289 scopus 로고    scopus 로고
    • Hdm4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis
    • Liang M, Han X, Vadhan-Raj S, et al. HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis. Mod Pathol. 2010;23:381-391.
    • (2010) Mod Pathol. , vol.23 , pp. 381-391
    • Liang, M.1    Han, X.2    Vadhan-Raj, S.3
  • 10
    • 4344608433 scopus 로고    scopus 로고
    • Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of flt3 gene mutations
    • Oyarzo MP, Lin P, Glassman A, et al. Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of flt3 gene mutations. Am J Clin Pathol. 2004;122:348-358.
    • (2004) Am J Clin Pathol. , vol.122 , pp. 348-358
    • Oyarzo, M.P.1    Lin, P.2    Glassman, A.3
  • 11
    • 79251510890 scopus 로고    scopus 로고
    • Acute myeloid leukemia with idh1 or idh2 mutation: Frequency and clinicopathologic features
    • Patel KP, Ravandi F, Ma D, et al. Acute myeloid leukemia with IDH1 or IDH2 mutation: frequency and clinicopathologic features. Am J Clin Pathol. 2011;135:35-45.
    • (2011) Am J Clin Pathol. , vol.135 , pp. 35-45
    • Patel, K.P.1    Ravandi, F.2    Ma, D.3
  • 12
    • 79251500335 scopus 로고    scopus 로고
    • Flt3 and npm1 mutations in myelodysplastic syndromes: Frequency and potential value for predicting progression to acute myeloid leukemia
    • Bains A, Luthra R, Medeiros LJ, et al. FLT3 and NPM1 mutations in myelodysplastic syndromes: frequency and potential value for predicting progression to acute myeloid leukemia. Am J Clin Pathol. 2011;1:62-69.
    • (2011) Am J Clin Pathol. , vol.1 , pp. 62-69
    • Bains, A.1    Luthra, R.2    Medeiros, L.J.3
  • 13
    • 84864219624 scopus 로고    scopus 로고
    • Acute myeloid leukemia (aml) with erythroid predominance exhibits clinical and molecular characteristics that differ from other types of aml
    • Zuo Z, Medeiros LJ, Chen Z, et al. Acute myeloid leukemia (AML) with erythroid predominance exhibits clinical and molecular characteristics that differ from other types of AML. PLoS One. 2012;7:e41485.
    • (2012) PLoS One. , vol.7
    • Zuo, Z.1    Medeiros, L.J.2    Chen, Z.3
  • 14
    • 9444283773 scopus 로고    scopus 로고
    • Gene expression profiling of pediatric acute myelogenous leukemia
    • Ross ME, Mahfouz R, Onciu M, et al. Gene expression profiling of pediatric acute myelogenous leukemia. Blood. 2004;12:3679-3687.
    • (2004) Blood. , vol.12 , pp. 3679-3687
    • Ross, M.E.1    Mahfouz, R.2    Onciu, M.3
  • 15
    • 63849241865 scopus 로고    scopus 로고
    • Double cebpa mutations, but not single cebpa mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome
    • Wouters BJ, Lowenberg B, Erpelinck-Verschueren CA, et al. Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome. Blood. 2009;13:3088-3091.
    • (2009) Blood. , vol.13 , pp. 3088-3091
    • Wouters, B.J.1    Lowenberg, B.2    Erpelinck-Verschueren, C.A.3
  • 16
    • 77955134007 scopus 로고    scopus 로고
    • Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: Report from the international microarray innovations in leukemia study group
    • Haferlach T, Kohlmann A, Wieczorek L, et al. Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group. J Clin Oncol. 2010;15:2529-2537.
    • (2010) J Clin Oncol. , vol.15 , pp. 2529-2537
    • Haferlach, T.1    Kohlmann, A.2    Wieczorek, L.3
  • 17
    • 11144358111 scopus 로고    scopus 로고
    • Prognostically useful gene-expression profiles in acute myeloid leukemia
    • Valk PJ, Verhaak RG, Beijen MA, et al. Prognostically useful gene-expression profiles in acute myeloid leukemia. N Engl J Med. 2004;16:1617-1628.
    • (2004) N Engl J Med. , vol.16 , pp. 1617-1628
    • Valk, P.J.1    Verhaak, R.G.2    Beijen, M.A.3
  • 18
    • 35948943103 scopus 로고    scopus 로고
    • Gene expression profiles that segregate patients with childhood acute lymphoblastic leukaemia: An independent validation study identifies that endoglin associates with patient outcome
    • Catchpoole D, Lail A, Guo D, et al. Gene expression profiles that segregate patients with childhood acute lymphoblastic leukaemia: an independent validation study identifies that endoglin associates with patient outcome. Leuk Res. 2007;31:1741-1747.
    • (2007) Leuk Res. , vol.31 , pp. 1741-1747
    • Catchpoole, D.1    Lail, A.2    Guo, D.3
  • 19
    • 33646480514 scopus 로고    scopus 로고
    • Flow cytometry evaluation of erythroid dysplasia in patients with myelodysplastic syndrome
    • Della Porta MG, Malcovati L, Invernizzi R, et al. Flow cytometry evaluation of erythroid dysplasia in patients with myelodysplastic syndrome. Leukemia. 2006;20:549-555.
    • (2006) Leukemia. , vol.20 , pp. 549-555
    • Della Porta, M.G.1    Malcovati, L.2    Invernizzi, R.3
  • 20
    • 0003050226 scopus 로고    scopus 로고
    • Cd105 workshop: Expression of cd105 on acute leukemia blast cells: Application for minimal residual disease detection
    • In: Kishimoto T, Kikutani H, von dem Borne AEGK, et al, eds. New York, NY:Garland
    • Lo Pardo C, Altomonte M, Boccuni P, et al. CD105 workshop: expression of CD105 on acute leukemia blast cells: application for minimal residual disease detection. In: Kishimoto T, Kikutani H, von dem Borne AEGK, et al, eds. Leucocyte Typing VI: White Cell Differentiation Antigens. New York, NY: Garland; 1998:711-712.
    • (1998) Leucocyte Typing VI: White Cell Differentiation Antigens , pp. 711-712
    • Lo Pardo, C.1    Altomonte, M.2    Boccuni, P.3
  • 21
    • 77956265489 scopus 로고    scopus 로고
    • Idh mutations in glioma and acute myeloid leukemia
    • Dang L, Jin S, Su SM. IDH mutations in glioma and acute myeloid leukemia. Trends Mol Med. 2010;16:387-397.
    • (2010) Trends Mol Med. , vol.16 , pp. 387-397
    • Dang, L.1    Jin, S.2    Su, S.M.3
  • 22
    • 77952536841 scopus 로고    scopus 로고
    • Idh1 and idh2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: A cancer and leukemia group b study
    • Marcucci G, Maharry K, Wu YZ, et al. IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. J Clin Oncol. 2010;28:2348-2355.
    • (2010) J Clin Oncol. , vol.28 , pp. 2348-2355
    • Marcucci, G.1    Maharry, K.2    Wu, Y.Z.3
  • 23
    • 77954573304 scopus 로고    scopus 로고
    • Idh1 and idh2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms
    • Pardanani A, Lasho TL, Finke CM, et al. IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms. Leukemia. 2010;24:1146-1151.
    • (2010) Leukemia. , vol.24 , pp. 1146-1151
    • Pardanani, A.1    Lasho, T.L.2    Finke, C.M.3
  • 24
    • 77952426827 scopus 로고    scopus 로고
    • Mutations of idh1 and idh2 genes in early and accelerated phases of myelodysplastic syndromes and mds/myeloproliferative neoplasms
    • Kosmider O, Gelsi-Boyer V, Slama L, et al. Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms. Leukemia. 2010;24:1094-1096.
    • (2010) Leukemia. , vol.24 , pp. 1094-1096
    • Kosmider, O.1    Gelsi-Boyer, V.2    Slama, L.3
  • 25
    • 84860791715 scopus 로고    scopus 로고
    • Idh1 and idh2 mutation analysis in chinese patients with acute myeloid leukemia and myelodysplastic syndrome
    • Lin J, Yao DM, Qian J, et al. IDH1 and IDH2 mutation analysis in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome. Ann Hematol. 2010;91:519-525.
    • (2010) Ann Hematol. , vol.91 , pp. 519-525
    • Lin, J.1    Yao, D.M.2    Qian, J.3
  • 26
    • 84857714230 scopus 로고    scopus 로고
    • Molecular alterations of isocitrate dehydrogenase 1 and 2 (idh1 and idh2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients
    • Chotirat S, Thongnoppakhun W, Promsuwicha O, et al. Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients. J Hematol Oncol. 2012;5:5.
    • (2012) J Hematol Oncol. , vol.5 , pp. 5
    • Chotirat, S.1    Thongnoppakhun, W.2    Promsuwicha, O.3
  • 27
    • 77957192661 scopus 로고    scopus 로고
    • Acquired mutations in the genes encoding idh1 and idh2 both are recurrent aberrations in acute myeloid leukemia: Prevalence and prognostic value
    • Abbas S, Lugthart S, Kavelaars FG, et al. Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value. Blood. 2010;116:2122-2126.
    • (2010) Blood. , vol.116 , pp. 2122-2126
    • Abbas, S.1    Lugthart, S.2    Kavelaars, F.G.3
  • 28
    • 84858796262 scopus 로고    scopus 로고
    • Idh mutation impairs histone demethylation and results in a block to cell differentiation
    • Lu C, Ward PS, Kapoor GS, et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature. 2012;483:474-478.
    • (2012) Nature. , vol.483 , pp. 474-478
    • Lu, C.1    Ward, P.S.2    Kapoor, G.S.3
  • 29
    • 84862548915 scopus 로고    scopus 로고
    • Acute myeloid leukemia with myelodysplasia-related changes are characterized by a specific molecular pattern with high frequency of asxl1 mutations
    • Devillier R, Gelsi-Boyer V, Brecqueville M, et al. Acute myeloid leukemia with myelodysplasia-related changes are characterized by a specific molecular pattern with high frequency of ASXL1 mutations. Am J Hematol. 2012;87:659-662.
    • (2012) Am J Hematol. , vol.87 , pp. 659-662
    • Devillier, R.1    Gelsi-Boyer, V.2    Brecqueville, M.3
  • 30
    • 84863393263 scopus 로고    scopus 로고
    • Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
    • Patel JP, Gonen M, Figueroa ME, et al. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. N Engl J Med. 2012;366:1079-1089.
    • (2012) N Engl J Med. , vol.366 , pp. 1079-1089
    • Patel, J.P.1    Gonen, M.2    Figueroa, M.E.3
  • 31
    • 80054035931 scopus 로고    scopus 로고
    • Idh1 and idh2 mutations in pediatric acute leukemia
    • Andersson AK, Miller DW, Lynch JA, et al. IDH1 and IDH2 mutations in pediatric acute leukemia. Leukemia. 2011;25:1570-1577.
    • (2011) Leukemia. , vol.25 , pp. 1570-1577
    • Andersson, A.K.1    Miller, D.W.2    Lynch, J.A.3
  • 32
    • 0029117933 scopus 로고
    • Expression and prognostic significance of tgf-beta isotypes, latent tgf-beta 1 binding protein, tgf-beta type i and type ii receptors, and endoglin in normal ovary and ovarian neoplasms
    • Henriksen R, Gobl A, Wilander E, et al. Expression and prognostic significance of TGF-beta isotypes, latent TGF-beta 1 binding protein, TGF-beta type I and type II receptors, and endoglin in normal ovary and ovarian neoplasms. Lab Invest. 1995;73:213-220.
    • (1995) Lab Invest. , vol.73 , pp. 213-220
    • Henriksen, R.1    Gobl, A.2    Wilander, E.3
  • 33
    • 18744362140 scopus 로고    scopus 로고
    • Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion
    • Liu Y, Jovanovic B, Pins M, et al. Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion. Oncogene. 2002;21:8272-8281.
    • (2002) Oncogene. , vol.21 , pp. 8272-8281
    • Liu, Y.1    Jovanovic, B.2    Pins, M.3
  • 34
    • 36048973196 scopus 로고    scopus 로고
    • Endoglin inhibits prostate cancer motility via activation of the alk2-smad1 pathway
    • Craft CS, Romero D, Vary CP, et al. Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway. Oncogene. 2007;26:7240-7250.
    • (2007) Oncogene. , vol.26 , pp. 7240-7250
    • Craft, C.S.1    Romero, D.2    Vary, C.P.3
  • 35
    • 3142766904 scopus 로고    scopus 로고
    • Whole-mount prostate sections reveal differential endoglin expression in stromal, epithelial, and endothelial cells with the development of prostate cancer
    • Kassouf W, Ismail HR, Aprikian AG, et al. Whole-mount prostate sections reveal differential endoglin expression in stromal, epithelial, and endothelial cells with the development of prostate cancer. Prostate Cancer Prostatic Dis. 2004;7:105-110.
    • (2004) Prostate Cancer Prostatic Dis. , vol.7 , pp. 105-110
    • Kassouf, W.1    Ismail, H.R.2    Aprikian, A.G.3
  • 36
    • 79960605550 scopus 로고    scopus 로고
    • Endoglin (cd105) expression in ovarian serous carcinoma effusions is related to chemotherapy status
    • Bock AJ, Tuft Stavnes H, Kaern J, et al. Endoglin (CD105) expression in ovarian serous carcinoma effusions is related to chemotherapy status. Tumour Biol. 2011;32:589-596.
    • (2011) Tumour Biol. , vol.32 , pp. 589-596
    • Bock, A.J.1    Tuft Stavnes, H.2    Kaern, J.3
  • 37
    • 78349313430 scopus 로고    scopus 로고
    • Cd105 (endoglin) expression in breast carcinoma effusions is a marker of poor survival
    • Davidson B, Stavnes HT, Forsund M, et al. CD105 (endoglin) expression in breast carcinoma effusions is a marker of poor survival. Breast. 2010;19:493-498.
    • (2010) Breast. , vol.19 , pp. 493-498
    • Davidson, B.1    Stavnes, H.T.2    Forsund, M.3
  • 38
    • 84862576881 scopus 로고    scopus 로고
    • A critical role for endoglin in the emergence of blood during embryonic development
    • Borges L, Iacovino M, Mayerhofer T, et al. A critical role for endoglin in the emergence of blood during embryonic development. Blood. 2012;119:5417-5428.
    • (2012) Blood. , vol.119 , pp. 5417-5428
    • Borges, L.1    Iacovino, M.2    Mayerhofer, T.3
  • 39
    • 0035694705 scopus 로고    scopus 로고
    • Cd105 (endoglin) expression on hematopoietic stem/progenitor cells
    • Pierelli L, Bonanno G, Rutella S, et al. CD105 (endoglin) expression on hematopoietic stem/progenitor cells. Leuk Lymphoma. 2001;42:1195-1206.
    • (2001) Leuk Lymphoma. , vol.42 , pp. 1195-1206
    • Pierelli, L.1    Bonanno, G.2    Rutella, S.3
  • 40
    • 0037293932 scopus 로고    scopus 로고
    • Differential levels of soluble endoglin (cd105) in myeloid malignancies
    • Calabrò L, Fonsatti E, Bellomo G, et al. Differential levels of soluble endoglin (CD105) in myeloid malignancies. J Cell Physiol. 2003;194:171-175.
    • (2003) J Cell Physiol. , vol.194 , pp. 171-175
    • Calabrò, L.1    Fonsatti, E.2    Bellomo, G.3


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