메뉴 건너뛰기




Volumn 63, Issue 5, 2013, Pages 389-396

Activation of ERK signaling in rostral ventromedial medulla is dependent on afferent input from dorsal column pathway and contributes to acetic acid-induced visceral nociception

Author keywords

Dorsal column; Rostral ventromedial medulla; Signal transduction; Visceral pain

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ACETIC ACID; LIDOCAINE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE;

EID: 84882780399     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2013.07.005     Document Type: Article
Times cited : (6)

References (41)
  • 1
    • 33846905925 scopus 로고    scopus 로고
    • NK-1 receptors modulate the excitability of on cells in the rostral ventromedial medulla
    • DOI 10.1152/jn.00450.2006
    • D. Budai, S.G. Khasabov, P.W. Mantyh, and D.A. Simone NK-1 receptors modulate the excitability of ON cells in the rostral ventromedial medulla J. Neurophysiol. 97 2007 1388 1395 (Pubitemid 46239515)
    • (2007) Journal of Neurophysiology , vol.97 , Issue.2 , pp. 1388-1395
    • Budai, D.1    Khasabov, S.G.2    Mantyh, P.W.3    Simone, D.A.4
  • 3
    • 0032188778 scopus 로고    scopus 로고
    • Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia
    • DOI 10.1016/S0304-3959(98)00137-7, PII S0304395998001377
    • S.V. Coutinho, M.O. Urban, and G.F. Gebhart Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia Pain 78 1998 59 69 (Pubitemid 28451529)
    • (1998) Pain , vol.78 , Issue.1 , pp. 59-69
    • Coutinho, S.V.1    Urban, M.O.2    Gebhart, G.F.3
  • 4
    • 0037095759 scopus 로고    scopus 로고
    • Calcium-Calmodulin-Dependent Protein Kinase II Contributes to Spinal Cord Central Sensitization
    • L. Fang, J. Wu, Q. Lin, and W.D. Willis Calcium-calmodulin-dependent protein kinase II contributes to spinal cord central sensitization J. Neurosci. 22 2002 4196 4204 (Pubitemid 37465726)
    • (2002) Journal of Neuroscience , vol.22 , Issue.10 , pp. 4196-4204
    • Fang, L.1    Wu, J.2    Lin, Q.3    Willis, W.D.4
  • 5
    • 0037370351 scopus 로고    scopus 로고
    • Gabapentin markedly reduces acetic acid-induced visceral nociception
    • DOI 10.1097/00000542-200303000-00023
    • Y. Feng, M. Cui, and W.D. Willis Gabapentin markedly reduces acetic acid-induced visceral nociception Anesthesiology 98 2003 729 733 (Pubitemid 36262602)
    • (2003) Anesthesiology , vol.98 , Issue.3 , pp. 729-733
    • Feng, Y.1    Cui, M.2    Willis, W.D.3
  • 6
    • 0028843805 scopus 로고
    • Dorsal horn projection targets of on and off cells in the rostral ventromedial medulla
    • H.L. Fields, A. Malick, and R. Burstein Dorsal horn projection targets of ON and OFF cells in the rostral ventromedial medulla J. Neurophysiol. 74 1995 1742 1759
    • (1995) J. Neurophysiol. , vol.74 , pp. 1742-1759
    • Fields, H.L.1    Malick, A.2    Burstein, R.3
  • 7
    • 74549130005 scopus 로고    scopus 로고
    • C-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?
    • Y.J. Gao, and R.R. Ji C-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury? Open Pain J. 2 2009 11 17
    • (2009) Open Pain J. , vol.2 , pp. 11-17
    • Gao, Y.J.1    Ji, R.R.2
  • 8
    • 77956456636 scopus 로고    scopus 로고
    • Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina i projection pathway
    • S.M. Geranton, K.K. Tochiki, W.W. Chiu, S.A. Stuart, and S.P. Hunt Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina I projection pathway Mol. Pain 6 2010 54
    • (2010) Mol. Pain , vol.6 , pp. 54
    • Geranton, S.M.1    Tochiki, K.K.2    Chiu, W.W.3    Stuart, S.A.4    Hunt, S.P.5
  • 9
    • 0028228154 scopus 로고
    • Activity at phencyclidine and mu opioid sites mediates the hyperalgesic and antinociceptive properties of the N-terminus of Substance P in a model of visceral pain
    • V.M. Goettl, and A.A. Larson Activity at phencyclidine and mu opioid sites mediates the hyperalgesic and antinociceptive properties of the N-terminus of Substance P in a model of visceral pain Neuroscience 60 1994 375 382
    • (1994) Neuroscience , vol.60 , pp. 375-382
    • Goettl, V.M.1    Larson, A.A.2
  • 10
    • 80052589278 scopus 로고    scopus 로고
    • Spinal 5-HT(3) receptor activation induces behavioral hypersensitivity via a neuronal-glial-neuronal signaling cascade
    • M. Gu, K. Miyoshi, R. Dubner, W. Guo, S. Zou, K. Ren, K. Noguchi, and F. Wei Spinal 5-HT(3) receptor activation induces behavioral hypersensitivity via a neuronal-glial-neuronal signaling cascade J. Neurosci. 31 2011 12823 12836
    • (2011) J. Neurosci. , vol.31 , pp. 12823-12836
    • Gu, M.1    Miyoshi, K.2    Dubner, R.3    Guo, W.4    Zou, S.5    Ren, K.6    Noguchi, K.7    Wei, F.8
  • 11
    • 0036156527 scopus 로고    scopus 로고
    • Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammation
    • Y. Guan, R. Terayama, R. Dubner, and K. Ren Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammation J. Pharmacol. Exp. Ther. 300 2002 513 520
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 513-520
    • Guan, Y.1    Terayama, R.2    Dubner, R.3    Ren, K.4
  • 12
    • 30644477580 scopus 로고    scopus 로고
    • Supraspinal brain-derived neurotrophic factor signaling: A novel mechanism for descending pain facilitation
    • DOI 10.1523/JNEUROSCI.3686-05.2006
    • W. Guo, M.T. Robbins, F. Wei, S. Zou, R. Dubner, and K. Ren Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation J. Neurosci. 26 2006 126 137 (Pubitemid 43089525)
    • (2006) Journal of Neuroscience , vol.26 , Issue.1 , pp. 126-137
    • Guo, W.1    Robbins, M.T.2    Wei, F.3    Zou, S.4    Dubner, R.5    Ren, K.6
  • 13
    • 84862777749 scopus 로고    scopus 로고
    • Chemokine signaling involving chemokine (C-C motif) ligand 2 plays a role in descending pain facilitation
    • W. Guo, H. Wang, S. Zou, R. Dubner, and K. Ren Chemokine signaling involving chemokine (C-C motif) ligand 2 plays a role in descending pain facilitation Neurosci. Bull. 28 2012 193 207
    • (2012) Neurosci. Bull. , vol.28 , pp. 193-207
    • Guo, W.1    Wang, H.2    Zou, S.3    Dubner, R.4    Ren, K.5
  • 14
    • 33845867162 scopus 로고    scopus 로고
    • Punctate Midline Myelotomy: A Minimally Invasive Procedure for the Treatment of Pain in Inextirpable Abdominal and Pelvic Cancer
    • DOI 10.1016/j.jpainsymman.2006.06.012, PII S0885392406005513
    • D. Hong, and A. Andren-Sandberg Punctate midline myelotomy: a minimally invasive procedure for the treatment of pain in inextirpable abdominal and pelvic cancer J. Pain Symptom Manage. 33 2007 99 109 (Pubitemid 46017077)
    • (2007) Journal of Pain and Symptom Management , vol.33 , Issue.1 , pp. 99-109
    • Hong, D.1    Andren-Sandberg, A.2
  • 15
    • 36749034827 scopus 로고    scopus 로고
    • Activation of ERK in the rostral ventromedial medulla is involved in hyperalgesia during peripheral inflammation
    • DOI 10.1016/j.brainres.2007.10.075, PII S0006899307025747
    • H. Imbe, A. Kimura, K. Okamoto, T. Donishi, F. Aikawa, E. Senba, and Y. Tamai Activation of ERK in the rostral ventromedial medulla is involved in hyperalgesia during peripheral inflammation Brain Res. 1187 2008 103 110 (Pubitemid 350199544)
    • (2008) Brain Research , vol.1187 , Issue.1 , pp. 103-110
    • Imbe, H.1    Kimura, A.2    Okamoto, K.3    Donishi, T.4    Aikawa, F.5    Senba, E.6    Tamai, Y.7
  • 16
    • 9244251049 scopus 로고    scopus 로고
    • The effects of acute and chronic restraint stress on activation of ERK in the rostral ventromedial medulla and locus coeruleus
    • DOI 10.1016/j.pain.2004.09.015, PII S0304395904004439
    • H. Imbe, S. Murakami, K. Okamoto, Y. Iwai-Liao, and E. Senba The effects of acute and chronic restraint stress on activation of ERK in the rostral ventromedial medulla and locus coeruleus Pain 112 2004 361 371 (Pubitemid 39550737)
    • (2004) Pain , vol.112 , Issue.3 , pp. 361-371
    • Imbe, H.1    Murakami, S.2    Okamoto, K.3    Iwai-Liao, Y.4    Senba, E.5
  • 17
    • 33846352239 scopus 로고    scopus 로고
    • Effects of peripheral inflammation on activation of p38 mitogen-activated protein kinase in the rostral ventromedial medulla
    • DOI 10.1016/j.brainres.2006.11.091, PII S0006899306035049
    • H. Imbe, K. Okamoto, F. Aikawa, A. Kimura, T. Donishi, Y. Tamai, Y. Iwai-Liao, and E. Senba Effects of peripheral inflammation on activation of p38 mitogen-activated protein kinase in the rostral ventromedial medulla Brain Res. 1134 2007 131 139 (Pubitemid 46135545)
    • (2007) Brain Research , vol.1134 , Issue.1 , pp. 131-139
    • Imbe, H.1    Okamoto, K.2    Aikawa, F.3    Kimura, A.4    Donishi, T.5    Tamai, Y.6    Iwai-Liao, Y.7    Senba, E.8
  • 18
    • 28444432293 scopus 로고    scopus 로고
    • Effects of peripheral inflammation on activation of ERK in the rostral ventromedial medulla
    • DOI 10.1016/j.brainres.2005.09.057, PII S0006899305013156
    • H. Imbe, K. Okamoto, T. Okamura, S. Kumabe, M. Nakatsuka, F. Aikawa, Y. Iwai-Liao, and E. Senba Effects of peripheral inflammation on activation of ERK in the rostral ventromedial medulla Brain Res. 1063 2005 151 158 (Pubitemid 41741026)
    • (2005) Brain Research , vol.1063 , Issue.2 , pp. 151-158
    • Imbe, H.1    Okamoto, K.2    Okamura, T.3    Kumabe, S.4    Nakatsuka, M.5    Aikawa, F.6    Iwai-Liao, Y.7    Senba, E.8
  • 20
    • 78650169017 scopus 로고    scopus 로고
    • Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla
    • S.C. Lagraize, W. Guo, K. Yang, F. Wei, K. Ren, and R. Dubner Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla Neuroscience 171 2010 1341 1356
    • (2010) Neuroscience , vol.171 , pp. 1341-1356
    • Lagraize, S.C.1    Guo, W.2    Yang, K.3    Wei, F.4    Ren, K.5    Dubner, R.6
  • 21
    • 84861176769 scopus 로고    scopus 로고
    • Inhibition of glial activation in rostral ventromedial medulla attenuates mechanical allodynia in a rat model of cancer-induced bone pain
    • X. Liu, H. Bu, C. Liu, F. Gao, H. Yang, X. Tian, A. Xu, Z. Chen, F. Cao, and Y. Tian Inhibition of glial activation in rostral ventromedial medulla attenuates mechanical allodynia in a rat model of cancer-induced bone pain J. Huazhong Univ. Sci. Technol. Med. Sci. 32 2012 291 298
    • (2012) J. Huazhong Univ. Sci. Technol. Med. Sci. , vol.32 , pp. 291-298
    • Liu, X.1    Bu, H.2    Liu, C.3    Gao, F.4    Yang, H.5    Tian, X.6    Xu, A.7    Chen, Z.8    Cao, F.9    Tian, Y.10
  • 22
    • 77956929107 scopus 로고    scopus 로고
    • Effects of anesthetic propofol on release of amino acids from the spinal cord during visceral pain
    • X. Mu, A. Wu, J. Wu, Y. Liu, Y. Zhang, Y. Yue, L. Fang, and Y. Wang Effects of anesthetic propofol on release of amino acids from the spinal cord during visceral pain Neurosci. Lett. 484 2010 206 209
    • (2010) Neurosci. Lett. , vol.484 , pp. 206-209
    • Mu, X.1    Wu, A.2    Wu, J.3    Liu, Y.4    Zhang, Y.5    Yue, Y.6    Fang, L.7    Wang, Y.8
  • 23
    • 0031036861 scopus 로고    scopus 로고
    • Surgical interruption of a midline dorsal column visceral pain pathway. Case report and review of the literature
    • H.J. Nauta, E. Hewitt, K.N. Westlund, and W.D. Willis Jr. Surgical interruption of a midline dorsal column visceral pain pathway. Case report and review of the literature J. Neurosurg. 86 1997 538 542 (Pubitemid 27097102)
    • (1997) Journal of Neurosurgery , vol.86 , Issue.3 , pp. 538-542
    • Nauta, H.J.W.1    Hewitt, E.2    Westlund, K.N.3    Willis Jr., W.D.4
  • 24
    • 2342491603 scopus 로고    scopus 로고
    • The role of dorsal columns pathway in visceral pain
    • J. Palecek The role of dorsal columns pathway in visceral pain Physiol. Res. 53 Suppl 1 2004 S125 S130
    • (2004) Physiol. Res. , vol.53 , Issue.SUPPL. 1
    • Palecek, J.1
  • 25
    • 0036216482 scopus 로고    scopus 로고
    • The roles of pathways in the spinal cord lateral and dorsal funiculi in signaling nociceptive somatic and visceral stimuli in rats
    • DOI 10.1016/S0304-3959(01)00459-6, PII S0304395901004596
    • J. Palecek, V. Paleckova, and W.D. Willis The roles of pathways in the spinal cord lateral and dorsal funiculi in signaling nociceptive somatic and visceral stimuli in rats Pain 96 2002 297 307 (Pubitemid 34327876)
    • (2002) Pain , vol.96 , Issue.3 , pp. 297-307
    • Palecek, J.1    Paleckova, V.2    Willis, W.D.3
  • 26
    • 67651154614 scopus 로고    scopus 로고
    • Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity
    • J. Roberts, M.H. Ossipov, and F. Porreca Glial activation in the rostroventromedial medulla promotes descending facilitation to mediate inflammatory hypersensitivity Eur. J. Neurosci. 30 2009 229 241
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 229-241
    • Roberts, J.1    Ossipov, M.H.2    Porreca, F.3
  • 27
    • 74749100610 scopus 로고    scopus 로고
    • Role of RVM neurons in capsaicin-evoked visceral nociception and referred hyperalgesia
    • R. Sanoja, V. Tortorici, C. Fernandez, T.J. Price, and F. Cervero Role of RVM neurons in capsaicin-evoked visceral nociception and referred hyperalgesia Eur. J. Pain 14 2010 120 129
    • (2010) Eur. J. Pain , vol.14 , pp. 120-129
    • Sanoja, R.1    Tortorici, V.2    Fernandez, C.3    Price, T.J.4    Cervero, F.5
  • 28
    • 84861827970 scopus 로고    scopus 로고
    • Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats
    • S. Sikandar, K. Bannister, and A.H. Dickenson Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats Neurosci. Lett. 519 2012 31 36
    • (2012) Neurosci. Lett. , vol.519 , pp. 31-36
    • Sikandar, S.1    Bannister, K.2    Dickenson, A.H.3
  • 29
    • 0036270528 scopus 로고    scopus 로고
    • The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation
    • DOI 10.1016/S0304-3959(02)00017-9, PII S0304395902000179
    • R. Terayama, R. Dubner, and K. Ren The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation Pain 97 2002 171 181 (Pubitemid 34603320)
    • (2002) Pain , vol.97 , Issue.1-2 , pp. 171-181
    • Terayama, R.1    Dubner, R.2    Ren, K.3
  • 30
    • 0035125645 scopus 로고    scopus 로고
    • Tolerance to repeated microinjection of morphine into the periaqueductal gray is associated with changes in the behavior of off- and on-cells in the rostral ventromedial medulla of rats
    • DOI 10.1016/S0304-3959(00)00367-5, PII S0304395900003675
    • V. Tortorici, M.M. Morgan, and H. Vanegas Tolerance to repeated microinjection of morphine into the periaqueductal gray is associated with changes in the behavior of off- and on-cells in the rostral ventromedial medulla of rats Pain 89 2001 237 244 (Pubitemid 32146403)
    • (2001) Pain , vol.89 , Issue.2-3 , pp. 237-244
    • Tortorici, V.1    Morgan, M.M.2    Vanegas, H.3
  • 31
    • 33744518427 scopus 로고    scopus 로고
    • Descending Facilitation From the Rostral Ventromedial Medulla Maintains Visceral Pain in Rats With Experimental Pancreatitis
    • DOI 10.1053/j.gastro.2006.03.025, PII S0016508506005749
    • L.P. Vera-Portocarrero, J.Y. Xie, J. Kowal, M.H. Ossipov, T. King, and F. Porreca Descending facilitation from the rostral ventromedial medulla maintains visceral pain in rats with experimental pancreatitis Gastroenterology 130 2006 2155 2164 (Pubitemid 43816956)
    • (2006) Gastroenterology , vol.130 , Issue.7 , pp. 2155-2164
    • Vera-Portocarrero, L.P.1    Yie, J.X.2    Kowal, J.3    Ossipov, M.H.4    King, T.5    Porreca, F.6
  • 32
    • 78650173721 scopus 로고    scopus 로고
    • NK-1-receptor-mediated lesion of spinal post-synaptic dorsal column neurons might improve intractable visceral pain of cancer origin
    • Y. Wang, X. Mu, Y. Liu, X. Zhang, A. Wu, and Y. Yue NK-1-receptor- mediated lesion of spinal post-synaptic dorsal column neurons might improve intractable visceral pain of cancer origin Med. Hypotheses 76 2011 102 104
    • (2011) Med. Hypotheses , vol.76 , pp. 102-104
    • Wang, Y.1    Mu, X.2    Liu, Y.3    Zhang, X.4    Wu, A.5    Yue, Y.6
  • 33
    • 78651322462 scopus 로고    scopus 로고
    • Differential roles of phosphorylated AMPA receptor GluR1 subunits at Serine-831 and Serine-845 sites in spinal cord dorsal horn in a rat model of post-operative pain
    • Y. Wang, X. Mu, J. Wu, A. Wu, L. Fang, J. Li, and Y. Yue Differential roles of phosphorylated AMPA receptor GluR1 subunits at Serine-831 and Serine-845 sites in spinal cord dorsal horn in a rat model of post-operative pain Neurochem. Res. 36 2011 170 176
    • (2011) Neurochem. Res. , vol.36 , pp. 170-176
    • Wang, Y.1    Mu, X.2    Wu, J.3    Wu, A.4    Fang, L.5    Li, J.6    Yue, Y.7
  • 34
    • 56649091454 scopus 로고    scopus 로고
    • Effects of general anesthetics on visceral pain transmission in the spinal cord
    • Y. Wang, J. Wu, Q. Lin, H. Nauta, Y. Yue, and L. Fang Effects of general anesthetics on visceral pain transmission in the spinal cord Mol. Pain 4 2008 50
    • (2008) Mol. Pain , vol.4 , pp. 50
    • Wang, Y.1    Wu, J.2    Lin, Q.3    Nauta, H.4    Yue, Y.5    Fang, L.6
  • 35
    • 77954136703 scopus 로고    scopus 로고
    • Molecular depletion of descending serotonin unmasks its novel facilitatory role in the development of persistent pain
    • F. Wei, R. Dubner, S. Zou, K. Ren, G. Bai, D. Wei, and W. Guo Molecular depletion of descending serotonin unmasks its novel facilitatory role in the development of persistent pain J. Neurosci. 30 2010 8624 8636
    • (2010) J. Neurosci. , vol.30 , pp. 8624-8636
    • Wei, F.1    Dubner, R.2    Zou, S.3    Ren, K.4    Bai, G.5    Wei, D.6    Guo, W.7
  • 37
    • 0035256761 scopus 로고    scopus 로고
    • The role of the dorsal column pathway in visceral nociception
    • W.D. Willis, and K.N. Westlund The role of the dorsal column pathway in visceral nociception Curr. Pain Headache Rep. 5 2001 20 26
    • (2001) Curr. Pain Headache Rep. , vol.5 , pp. 20-26
    • Willis, W.D.1    Westlund, K.N.2
  • 38
    • 0036083354 scopus 로고    scopus 로고
    • The role of nitric oxide in the phosphorylation of cyclic adenosine monophosphate-responsive element-binding protein in the spinal cord after intradermal injection of capsaicin
    • DOI 10.1054/jpai.2002.123653
    • J. Wu, L. Fang, Q. Lin, and W.D. Willis The role of nitric oxide in the phosphorylation of cyclic adenosine monophosphate-responsive element-binding protein in the spinal cord after intradermal injection of capsaicin J. Pain 3 2002 190 198 (Pubitemid 34663607)
    • (2002) Journal of Pain , vol.3 , Issue.3 , pp. 190-198
    • Wu, J.1    Fang, L.2    Lin, Q.3    Willis, W.D.4
  • 39
    • 33947421275 scopus 로고    scopus 로고
    • The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain
    • DOI 10.1016/j.neuint.2007.01.006, PII S0197018607000241
    • J. Wu, G. Su, L. Ma, X. Zhang, Y. Lei, Q. Lin, H.J. Nauta, J. Li, and L. Fang The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain Neurochem. Int. 50 2007 710 718 (Pubitemid 46452840)
    • (2007) Neurochemistry International , vol.50 , Issue.5 , pp. 710-718
    • Wu, J.1    Su, G.2    Ma, L.3    Zhang, X.4    Lei, Y.5    Lin, Q.6    Nauta, H.J.W.7    Li, J.8    Fang, L.9
  • 40
    • 79957887450 scopus 로고    scopus 로고
    • Rostral ventromedial medulla mu, but not kappa, opioid receptors are involved in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model
    • Y. Zhang, A. Li, L. Lao, J. Xin, K. Ren, B.M. Berman, and R.X. Zhang Rostral ventromedial medulla mu, but not kappa, opioid receptors are involved in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model Brain Res. 1395 2011 38 45
    • (2011) Brain Res. , vol.1395 , pp. 38-45
    • Zhang, Y.1    Li, A.2    Lao, L.3    Xin, J.4    Ren, K.5    Berman, B.M.6    Zhang, R.X.7
  • 41
    • 0036082813 scopus 로고    scopus 로고
    • Biphasic modulation of spinal visceral nociceptive transmission from the rostroventral medial medulla in the rat
    • M. Zhuo, J.N. Sengupta, and G.F. Gebhart Biphasic modulation of spinal visceral nociceptive transmission from the rostroventral medial medulla in the rat J. Neurophysiol. 87 2002 2225 2236 (Pubitemid 34670697)
    • (2002) Journal of Neurophysiology , vol.87 , Issue.5 , pp. 2225-2236
    • Zhuo, M.1    Sengupta, J.N.2    Gebhart, G.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.