Process development and scale-up for the preparation of the 1-methyl-quinazoline-2,4-dione wnt inhibitor SEN461

Organic Process Research and Development

Volumn 17, Issue 8, 2013, Pages 1042-1051

  Betti, Matteo ^a   Genesio, Eva ^a   Panico, Alessandro ^b   Sanna Coccone, Salvatore ^b   Wiedenau, Paul ^c  

^a Siena Biotech SpA   (Italy)

^b NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^c Aptuit Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRAM QUANTITIES; MEDICINAL CHEMISTRY; PHASE 1; PROCESS DEVELOPMENT; SCALE-UP; SCALE-UP PROCESS; SYNTHETIC PROCEDURES;

CHEMISTRY;

EID: 84882757818     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op400145w     Document Type: Article

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