In vitro and in vivo characterization of a tunable dual-reactivity probe of the Nrf2-ARE pathway

ACS Chemical Biology

Volumn 8, Issue 8, 2013, Pages 1764-1774

  Wang, Rui ^a   Mason, Daniel E ^b   Choe, Keith P ^a   Lewin, Alfred S ^a   Peters, Eric C ^b   Luesch, Hendrik ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AI 3; ANTIOXIDANT; CYSTEINE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; THIOL; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CAENORHABDITIS ELEGANS; CELL NUCLEUS; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG HALF LIFE; DRUG STABILITY; ELECTROPHILICITY; GENE ACTIVATION; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR PROBE; MOUSE; NONHUMAN; NUCLEOPHILICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SINGLE DRUG DOSE; STRUCTURE ACTIVITY RELATION; WORM;

ANIMALS; CAENORHABDITIS ELEGANS; CARBOXYLIC ESTER HYDROLASES; CELL LINE; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; HUMANS; MICE; MODELS, BIOLOGICAL; MOLECULAR PROBES; NF-E2-RELATED FACTOR 2; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES; THIOPHENES;

EID: 84882750108     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb4000103     Document Type: Article

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