Hypertension and vascular dementia in the elderly: The potential role of anti-hypertensive agents

Current Medical Research and Opinion

Volumn 29, Issue 9, 2013, Pages 1045-1054

  Coca, Antonio ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Anti hypertensive agents; Cognitive decline; Hypertension; Vascular dementia, calcium channel blockers

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ENALAPRIL; HYDROCHLOROTHIAZIDE PLUS LISINOPRIL; HYDROCHLOROTHIAZIDE PLUS TELMISARTAN; INDAPAMIDE; LERCANIDIPINE; NITRENDIPINE; PERINDOPRIL; TELMISARTAN;

ANTIHYPERTENSIVE THERAPY; ARTICLE; CEREBROVASCULAR ACCIDENT; COGNITION; EPISODIC MEMORY; FOLLOW UP; GERIATRIC PATIENT; HUMAN; HYPERTENSION; MINI MENTAL STATE EXAMINATION; MONOTHERAPY; MULTIINFARCT DEMENTIA; PROGNOSIS; PSYCHOLOGIC TEST; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENCE RISK; RISK REDUCTION; TRANSIENT ISCHEMIC ATTACK; TREATMENT RESPONSE; VERBAL BEHAVIOR;

AGED; AGED, 80 AND OVER; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; DEMENTIA, VASCULAR; FEMALE; HUMANS; HYPERTENSION; MALE; MEDLINE; MIDDLE AGED;

EID: 84882745766     PISSN: 03007995     EISSN: 14734877     Source Type: Journal    
DOI: 10.1185/03007995.2013.813841     Document Type: Article

References (38)

1. Aronow WS, Fleg JL, Pepine CJ, et al. ACCF/AHA 2011 expert consensus document on hypertension in the elderly. J Am Coll Cardiol 2011;57: 2037-114
2. Chang-Quan H, Hui W, Chao-Min W, et al. The association of antihypertensive medication use with risk of cognitive decline and dementia: A meta-analysis of longitudinal studies. Int J Clin Pract 2011;65:1295-305
3. Peters R, Beckett N. Hypertension, dementia, and antihypertensive treatment: Implications for the very elderly. Curr Hypertens Rep 2009;11:277-82
4. Sahathevan R, Brodtmann A, Donnan GA. Dementia, stroke, and vascular risk factors; a review. Int J Stroke 2012;7:61-73
5. Launer LJ, Masaki K, Petroviecb H, et al. The association between mid-life blood pressure levels and late-life cognitive function: The Honolulu-Asia aging study. JAMA 1995;274:1846-51
6. Haag MDM, Hofman A, Koudstaal PJ, et al. Duration of antihypertensive drug use and risk of dementia: A prospective cohort study. Neurology 2009;72:1727-34
7. Qiu C, Strauss E, Fastbom J, et al. Low blood pressure and risk of dementia in the Kungsholmen project. Arch Neurol 2003;60:223-8
8. Elias M, Wolf P, D'Agostino R, et al. Untreated blood pressure level is inversely related to cognitive functioning: The Framingham study. Am J Epidemiol 1993;138:353-64
9. Tzourio C, Dufouil C, Ducimetière P, et al. Cognitive decline in individuals with high blood pressure: A longitudinal study in the elderly. EVA Study Group. Epidemiology of Vascular Aging. Neurology 1999;53:1948-52
10. Skoog I, Lernfelt B, Landahl S, et al. 15-year longitudinal study of blood pressure and dementia. Lancet 1996;347:1141-5
11. Kivipelto M, Helkala E, Laakso M, et al. Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med 2002;137:149-55
12. Kilander L, Nyman H, Boberg M, et al. Hypertension is related to cognitive impairment: A 20-year follow-up of 999 men. Hypertension 1998;31:780-6
13. Ninomiya T, Ohara T, Hirakawa Y, et al. Midlife and late-life blood pressure and dementia in Japanese elderly: The Hisayama study. Hypertension 2011;58:22-8
14. Cherubini A, Lowenthal DT, Paran E, et al. Hypertension and cognitive function in the elderly. Dis Mon 2010;56:106-47
15. Vogt TM, Ireland CC, Black D, et al. Recruitment of elderly volunteer for multi-center clinical trial: The SHEP pilot study. Controlled Clin Trials 1986;7:118-33
16. Fletcher AE, Bulpitt CJ. How far should blood pressure be lowered? N Eng J Med 1992;326:251-4
17. Roman GC, Tatemichi TK, Erkinjutti T, et al. Vascular dementia: Diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 1993;43:250-60
18. In't Veld BA, Ruitenberg A, Hofman A, et al. Antihypertensive drugs and incidence of dementia: The Rotterdam Study. Neurobiol Aging 2001;22:407-12
19. Watfa G, Rossignol P, Kearney-Schwartz A, et al. Use of calcium channel blockers is associated with better cognitive performance in older hypertensive patients with subjective memory complaints. J Hypertens 2010;28: 2485-93
20. Davies NM, Kehoe PG, Ben-Shlomo Y, et al. Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias. J Alzheimers Dis 2011;26:699-708
21. PROGRESS Collaborative Group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001;358:1033-41
22. Tzourio C, Anderson C, Chapman N, et al. PROGRESS Collaborative Group. Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with CV disease. Arch Intern Med 2003;163:1069-75
23. Lithell H, Hansson L, Skoog I, et al. The Study on Cognition and Prognosis in the Elderly (SCOPE): Principal results of a randomized double-blind interventional trial. J Hypertens 2003;21:875-86
24. The Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: A randomised controlled trial. Lancet 2008;372:1174-83
25. The ONTARGET Investigators. Telmisartan, ramipril, or both in patients at high risk for vascular events. New Engl J Med 2008;358:1547-59
26. Fogari R, Mugellini A, Zoppi A, et al. Effect of telmisartan/ hydrochlorothiazide vs lisinopril/hydrochlorothiazide combination on ambulatory blood pressure and cognitive function in elderly hypertensive patients. J Hum Hypertens 2006;20:177-85
27. Fogari R, Mugellini A, Zoppi A, et al. Influence of losartan and atenolol on memory function in very elderly hypertensive patients. J Hum Hypertens 2003;17:781-5
28. Pèrez-Stable, Halliday R, Gardiner PS, et al. The effects of propranolol on cognitive function and quality of life: A randomized trial among patients with diastolic hypertension. Am J Med 2000;108:359-65
29. Peters R, Beckett N, Forette F, et al. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): A double-blind, placebo controlled trial. Lancet Neurol 2008;7:683-9
30. SHEP cooperative research group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated hypertension. JAMA 1991;265:3255-64
31. Forette F, Seux ML, Staessen JA, et al. Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial. Lancet 1998;352:1347-51
32. Forette F, Seux ML, Staessen JA, et al. The prevention of dementia with antihypertensive treatment: New evidence from the Systolic Hypertension in Europe (Syst-Eur) study. Arch Intern Med 2002;162:2046-52
33. Trompet S, Westendorp RG, Kamper AM, et al. Use of calcium antagonists and cognitive decline in old age. The Leiden 85-plus study. Neurobiol Aging 2008;29:306-8
34. Tisaire-Sá nchez J, Roma J, Camacho-Azcargorta I, et al. Assessment of cognitive function in patients with essential hypertension treated with lercanidipine. Vasc Health Risk Manag 2006;2:491-8
35. Yamada K, Horita T, Takayama M, et al. Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats. Brain Res 2011;1421:110-20
36. Kishi T, Hirooka Y, Sunagawa K. Telmisartan protects against cognitive decline via up-regulation of brain-derived neurotrophic factor/ tropomyosinrelated kinase B in hippocampus of hypertensive rats. J Cardiol 2012;60: 489-94
37. Sakurai-Yamashita Y, Harada N, Niwa M. Lercanidipine rescues hippocampus pyramidal neurons from mild ischemia-induced delayed neuronal death in SHRSP. Cell Mol Neurobiol 2011;31:561-7
38. Igase M, Kohara K, Miki T. The Association between Hypertension and Dementia in the Elderly. Int J Hypertens 2012;2012:320648