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Volumn 8, Issue 8, 2013, Pages 1830-1840

Donor assists acceptor binding and catalysis of human α1,6- fucosyltransferase

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1,6 FUCOSYLTRANSFERASE; AMINO ACID; BETA PHOSPHATE; FUCOSYLTRANSFERASE; GUANOSINE DIPHOSPHATE FUCOSE; HEXASACCHARIDE; N ACETYLGLUCOSAMINE; OXYGEN; POLYSACCHARIDE; UNCLASSIFIED DRUG;

EID: 84882744488     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400140u     Document Type: Article
Times cited : (22)

References (42)
  • 1
    • 77950459311 scopus 로고    scopus 로고
    • Glycosyltransferases and glycan-processing enzymes
    • in (Varki, A. Cummings, R. and Esko, J. Eds.) 2 nd ed. Cold Spring Harbor Laboratory Press, New York.
    • Rini, J., Esko, J., and Varki, A. (2009) Glycosyltransferases and glycan-processing enzymes, in Essentials of Glycobiology (Varki, A., Cummings, R., and Esko, J., Eds.) 2 nd ed., Cold Spring Harbor Laboratory Press, New York.
    • (2009) Essentials of Glycobiology
    • Rini, J.1    Esko, J.2    Varki, A.3
  • 2
    • 0038495798 scopus 로고    scopus 로고
    • Fucose: Biosynthesis and biological function in mammals
    • Becker, D. J. and Lowe, J. B. (2003) Fucose: biosynthesis and biological function in mammals Glycobiology 13, 41R-53R
    • (2003) Glycobiology , vol.13
    • Becker, D.J.1    Lowe, J.B.2
  • 3
    • 0017193878 scopus 로고
    • Control of glycoprotein synthesis: N-acetylglucosamine linkage to a mannose residue as a signal for attachment of L-fucose to asparagine-linked N-acetylglucosamine residue of glycopeptide from α1-acid glycoprotein
    • Wilson, J. R., Williams, D., and Schachter, H. (1976) Control of glycoprotein synthesis: N-acetylglucosamine linkage to a mannose residue as a signal for attachment of L-fucose to asparagine-linked N-acetylglucosamine residue of glycopeptide from α1-acid glycoprotein Biochem. Biophys. Res. Commun. 72, 909-916
    • (1976) Biochem. Biophys. Res. Commun. , vol.72 , pp. 909-916
    • Wilson, J.R.1    Williams, D.2    Schachter, H.3
  • 5
    • 33646384614 scopus 로고    scopus 로고
    • Core fucosylation regulates epidermal growth factor receptor-mediated intracellular signaling
    • Wang, X., Gu, J., Ihara, H., Miyoshi, E., Honke, K., and Taniguchi, N. (2006) Core fucosylation regulates epidermal growth factor receptor-mediated intracellular signaling J. Biol. Chem. 281, 2572-2577
    • (2006) J. Biol. Chem. , vol.281 , pp. 2572-2577
    • Wang, X.1    Gu, J.2    Ihara, H.3    Miyoshi, E.4    Honke, K.5    Taniguchi, N.6
  • 7
    • 66749177948 scopus 로고    scopus 로고
    • Requirement of Fut8 for the expression of vascular endothelial growth factor receptor-2: A new mechanism for the emphysema-like changes observed in Fut8-deficient mice
    • Wang, X., Fukuda, T., Li, W., Gao, C. X., Kondo, A., Matsumoto, A., Miyoshi, E., Taniguchi, N., and Gu, J. (2009) Requirement of Fut8 for the expression of vascular endothelial growth factor receptor-2: a new mechanism for the emphysema-like changes observed in Fut8-deficient mice J. Biochem. 145, 643-651
    • (2009) J. Biochem. , vol.145 , pp. 643-651
    • Wang, X.1    Fukuda, T.2    Li, W.3    Gao, C.X.4    Kondo, A.5    Matsumoto, A.6    Miyoshi, E.7    Taniguchi, N.8    Gu, J.9
  • 13
    • 0037178791 scopus 로고    scopus 로고
    • Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity
    • Shields, R. L., Lai, J., Keck, R., O'Connell, L. Y., Hong, K., Meng, Y. G., Weikert, S. H., and Presta, L. G. (2002) Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity J. Biol. Chem. 277, 26733-26740
    • (2002) J. Biol. Chem. , vol.277 , pp. 26733-26740
    • Shields, R.L.1    Lai, J.2    Keck, R.3    O'Connell, L.Y.4    Hong, K.5    Meng, Y.G.6    Weikert, S.H.7    Presta, L.G.8
  • 14
    • 0037474276 scopus 로고    scopus 로고
    • The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity
    • Shinkawa, T., Nakamura, K., Yamane, N., Shoji-Hosaka, E., Kanda, Y., Sakurada, M., Uchida, K., Anazawa, H., Satoh, M., Yamasaki, M., Hanai, N., and Shitara, K. (2003) The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity J. Biol. Chem. 278, 3466-3473
    • (2003) J. Biol. Chem. , vol.278 , pp. 3466-3473
    • Shinkawa, T.1    Nakamura, K.2    Yamane, N.3    Shoji-Hosaka, E.4    Kanda, Y.5    Sakurada, M.6    Uchida, K.7    Anazawa, H.8    Satoh, M.9    Yamasaki, M.10    Hanai, N.11    Shitara, K.12
  • 15
    • 84875189360 scopus 로고    scopus 로고
    • A non-ionic inhibitor with high specificity for the UDP-Gal donor binding site of human blood group B galactosyltransferase - Design, synthesis and characterization
    • Schaefer, K., Sindhuwinata, N., Hackl, T., Kötzler, M. P., Niemeyer, F. C., Palcic, M. M., Peters, T. H., and Meyer, B. (2013) A non-ionic inhibitor with high specificity for the UDP-Gal donor binding site of human blood group B galactosyltransferase-design, synthesis and characterization J. Med. Chem. 56, 2150-2154
    • (2013) J. Med. Chem. , vol.56 , pp. 2150-2154
    • Schaefer, K.1    Sindhuwinata, N.2    Hackl, T.3    Kötzler, M.P.4    Niemeyer, F.C.5    Palcic, M.M.6    Peters, T.H.7    Meyer, B.8
  • 16
    • 84856574217 scopus 로고    scopus 로고
    • A new concept for glycosyltransferase inhibitors: Nonionic mimics of the nucleotide donor of the human blood group B galactosyltransferase
    • Schaefer, K., Albers, J., Sindhuwinata, N., Peters, T., and Meyer, B. (2012) A new concept for glycosyltransferase inhibitors: Nonionic mimics of the nucleotide donor of the human blood group B galactosyltransferase ChemBioChem 13, 443-450
    • (2012) ChemBioChem , vol.13 , pp. 443-450
    • Schaefer, K.1    Albers, J.2    Sindhuwinata, N.3    Peters, T.4    Meyer, B.5
  • 17
    • 0346018747 scopus 로고    scopus 로고
    • Glycosyltransferase inhibitors
    • in (Wong, C.-H. Ed.) 1 st ed. pp, Wiley-VCH, Weinheim. - 659
    • Schmidt, R. R. and Jung, K.-H. (2003) Glycosyltransferase inhibitors, in Carbohydrate-based Drug Discovery (Wong, C.-H., Ed.) 1 st ed., pp 609-659, Wiley-VCH, Weinheim.
    • (2003) Carbohydrate-based Drug Discovery , pp. 609
    • Schmidt, R.R.1    Jung, K.-H.2
  • 19
    • 0025789667 scopus 로고
    • Purification and characterization of GDP-L-fucose-N-acetyl β-D-glucosaminide α1,6-fucosyltransferase from cultured human skin fibroblasts. Requirement of a specific biantennary oligosaccharide as substrate
    • Voynow, J. A., Kaiser, R. S., Scanlin, T. F., and Glick, M. C. (1991) Purification and characterization of GDP-L-fucose-N-acetyl β-D- glucosaminide α1,6-fucosyltransferase from cultured human skin fibroblasts. Requirement of a specific biantennary oligosaccharide as substrate J. Biol. Chem. 266, 21572-21577
    • (1991) J. Biol. Chem. , vol.266 , pp. 21572-21577
    • Voynow, J.A.1    Kaiser, R.S.2    Scanlin, T.F.3    Glick, M.C.4
  • 20
    • 0345099482 scopus 로고    scopus 로고
    • A new superfamily of protein-O-fucosyltransferases, α2- fucosyltransferases, and α6-fucosyltransferases: Phylogeny and identification of conserved peptide motifs
    • Martinez-Duncker, I., Mollicone, R., Candelier, J. J., Breton, C., and Oriol, R. (2003) A new superfamily of protein-O-fucosyltransferases, α2-fucosyltransferases, and α6-fucosyltransferases: phylogeny and identification of conserved peptide motifs Glycobiology 13, 1C-5C
    • (2003) Glycobiology , vol.13
    • Martinez-Duncker, I.1    Mollicone, R.2    Candelier, J.J.3    Breton, C.4    Oriol, R.5
  • 21
    • 0031794255 scopus 로고    scopus 로고
    • Purification and characterization of GDP-L-Fuc: N-acetyl β-D-glucosaminide α1,6-fucosyltransferase from human blood platelets
    • Kaminska, J., Glick, M. C., and Koscielak, J. (1998) Purification and characterization of GDP-L-Fuc: N-acetyl β-D-glucosaminide α1,6-fucosyltransferase from human blood platelets Glycoconjugate J. 15, 783-788
    • (1998) Glycoconjugate J. , vol.15 , pp. 783-788
    • Kaminska, J.1    Glick, M.C.2    Koscielak, J.3
  • 22
    • 0020108081 scopus 로고
    • Product-identification and substrate-specificity studies of the GDP-L-fucose:2-acetamido-2-deoxy-β-D-glucoside (FUC goes to Asn-linked GlcNAc) 6-α-L-fucosyltransferase in a Golgi-rich fraction from porcine liver
    • Longmore, G. D. and Schachter, H. (1982) Product-identification and substrate-specificity studies of the GDP-L-fucose:2-acetamido-2-deoxy-β-D- glucoside (FUC goes to Asn-linked GlcNAc) 6-α-L-fucosyltransferase in a Golgi-rich fraction from porcine liver Carbohydr. Res. 100, 365-392
    • (1982) Carbohydr. Res. , vol.100 , pp. 365-392
    • Longmore, G.D.1    Schachter, H.2
  • 23
    • 24044466162 scopus 로고    scopus 로고
    • Fucosyltransferase substrate specificity and the order of fucosylation in invertebrates
    • Paschinger, K., Staudacher, E., Stemmer, U., Fabini, G., and Wilson, I. B. (2005) Fucosyltransferase substrate specificity and the order of fucosylation in invertebrates Glycobiology 15, 463-474
    • (2005) Glycobiology , vol.15 , pp. 463-474
    • Paschinger, K.1    Staudacher, E.2    Stemmer, U.3    Fabini, G.4    Wilson, I.B.5
  • 24
    • 0028762195 scopus 로고
    • Specificity studies of the GDP-L-fucose - 2-acetamido-2-deoxy-β-D- glucoside (Fuc-Asn-linked GlcNAc) 6-α-fucosyl-transferase from rat-liver golgi membranes
    • Shao, M. C., Sokolik, C. W., and Wold, F. (1994) Specificity studies of the GDP-L-fucose-2-acetamido-2-deoxy-β-D-glucoside (Fuc-Asn-linked GlcNAc) 6-α-fucosyl-transferase from rat-liver golgi membranes Carbohydr. Res. 251, 163-173
    • (1994) Carbohydr. Res. , vol.251 , pp. 163-173
    • Shao, M.C.1    Sokolik, C.W.2    Wold, F.3
  • 25
    • 33645107042 scopus 로고    scopus 로고
    • Reaction mechanism and substrate specificity for nucleotide sugar of mammalian α1,6-fucosyltransferase - A large-scale preparation and characterization of recombinant human FUT8
    • Ihara, H., Ikeda, Y., and Taniguchi, N. (2006) Reaction mechanism and substrate specificity for nucleotide sugar of mammalian α1,6- fucosyltransferase-a large-scale preparation and characterization of recombinant human FUT8 Glycobiology 16, 333-342
    • (2006) Glycobiology , vol.16 , pp. 333-342
    • Ihara, H.1    Ikeda, Y.2    Taniguchi, N.3
  • 26
    • 84856429877 scopus 로고    scopus 로고
    • Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose
    • Brzezinski, K., Dauter, Z., and Jaskolski, M. (2012) Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose Acta Crystallogr. D 68, 160-168
    • (2012) Acta Crystallogr. D , vol.68 , pp. 160-168
    • Brzezinski, K.1    Dauter, Z.2    Jaskolski, M.3
  • 28
    • 34248186582 scopus 로고    scopus 로고
    • Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design
    • Sun, H. Y., Lin, S. W., Ko, T. P., Pan, J. F., Liu, C. L., Lin, C. N., Wang, A. H., and Lin, C. H. (2007) Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design J. Biol. Chem. 282, 9973-9982
    • (2007) J. Biol. Chem. , vol.282 , pp. 9973-9982
    • Sun, H.Y.1    Lin, S.W.2    Ko, T.P.3    Pan, J.F.4    Liu, C.L.5    Lin, C.N.6    Wang, A.H.7    Lin, C.H.8
  • 29
    • 84855586936 scopus 로고    scopus 로고
    • Formation of the immunogenic α1,3-fucose epitope: Elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A
    • Kötzler, M. P., Blank, S., Behnken, H. N., Alpers, D., Bantleon, F. I., Spillner, E., and Meyer, B. (2012) Formation of the immunogenic α1,3-fucose epitope: Elucidation of substrate specificity and of enzyme mechanism of core fucosyltransferase A Insect Biochem. Mol. Biol. 42, 116-125
    • (2012) Insect Biochem. Mol. Biol. , vol.42 , pp. 116-125
    • Kötzler, M.P.1    Blank, S.2    Behnken, H.N.3    Alpers, D.4    Bantleon, F.I.5    Spillner, E.6    Meyer, B.7
  • 30
    • 48349091000 scopus 로고    scopus 로고
    • Temperature-dependent cooperativity in donor-acceptor substrate binding to the human blood group glycosyltransferases
    • Shoemaker, G. K., Soya, N., Palcic, M. M., and Klassen, J. S. (2008) Temperature-dependent cooperativity in donor-acceptor substrate binding to the human blood group glycosyltransferases Glycobiology 18, 587-592
    • (2008) Glycobiology , vol.18 , pp. 587-592
    • Shoemaker, G.K.1    Soya, N.2    Palcic, M.M.3    Klassen, J.S.4
  • 32
    • 11844280851 scopus 로고    scopus 로고
    • Substrate-induced conformational changes in glycosyltransferases
    • Qasba, P. K., Ramakrishnan, B., and Boeggeman, E. (2005) Substrate-induced conformational changes in glycosyltransferases Trends Biochem. Sci. 30, 53-62
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 53-62
    • Qasba, P.K.1    Ramakrishnan, B.2    Boeggeman, E.3
  • 34
    • 84866661292 scopus 로고    scopus 로고
    • Donor substrate binding and enzymatic mechanism of human core α1,6-fucosyltransferase (FUT8)
    • Kötzler, M. P., Blank, S., Bantleon, F. I., Spillner, E., and Meyer, B. (2012) Donor substrate binding and enzymatic mechanism of human core α1,6-fucosyltransferase (FUT8) Biochim. Biophys. Acta 1915-1925
    • (2012) Biochim. Biophys. Acta , pp. 1915-1925
    • Kötzler, M.P.1    Blank, S.2    Bantleon, F.I.3    Spillner, E.4    Meyer, B.5
  • 35
    • 0033553844 scopus 로고    scopus 로고
    • Characterization of ligand binding by saturation transfer difference NMR spectroscopy
    • Mayer, M. and Meyer, B. (1999) Characterization of ligand binding by saturation transfer difference NMR spectroscopy Angew. Chem., Int. Ed. 38, 1784-1788
    • (1999) Angew. Chem., Int. Ed. , vol.38 , pp. 1784-1788
    • Mayer, M.1    Meyer, B.2
  • 36
    • 0034823890 scopus 로고    scopus 로고
    • Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor
    • Mayer, M. and Meyer, B. (2001) Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor J. Am. Chem. Soc. 123, 6108-6117
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 6108-6117
    • Mayer, M.1    Meyer, B.2
  • 37
    • 10944261243 scopus 로고    scopus 로고
    • Understanding noncovalent interactions: Ligand binding energy and catalytic efficiency from ligand-induced reductions in motion within receptors and enzymes
    • Williams, D. H., Stephens, E., O'Brien, D. P., and Zhou, M. (2004) Understanding noncovalent interactions: Ligand binding energy and catalytic efficiency from ligand-induced reductions in motion within receptors and enzymes Angew. Chem., Int. Ed. 43, 6596-6616
    • (2004) Angew. Chem., Int. Ed. , vol.43 , pp. 6596-6616
    • Williams, D.H.1    Stephens, E.2    O'Brien, D.P.3    Zhou, M.4
  • 38
    • 84985201137 scopus 로고
    • Confomational analysis, XXIV. Determination of the conformations of tri-and tetrasaccharide sequences of N-glycoproteins. The problem of the 1,6-glycosidic bond
    • Paulsen, H., Peters, T., Sinnwell, V., Lebuhn, R., and Meyer, B. (1984) Confomational analysis, XXIV. Determination of the conformations of tri-and tetrasaccharide sequences of N-glycoproteins. The problem of the 1,6-glycosidic bond Liebigs Ann. Chem. 1984, 951-976
    • (1984) Liebigs Ann. Chem. , vol.1984 , pp. 951-976
    • Paulsen, H.1    Peters, T.2    Sinnwell, V.3    Lebuhn, R.4    Meyer, B.5
  • 42
    • 0031039932 scopus 로고    scopus 로고
    • Mechanism of human α1,3-fucosyltransferase V: Glycosidic cleavage occurs prior to nucleophilic attack
    • Murray, B. W., Wittmann, V., Burkart, M. D., Hung, S. C., and Wong, C. H. (1997) Mechanism of human α1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack Biochemistry 36, 823-831
    • (1997) Biochemistry , vol.36 , pp. 823-831
    • Murray, B.W.1    Wittmann, V.2    Burkart, M.D.3    Hung, S.C.4    Wong, C.H.5


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